t(3;6)(q27;p21) BCL6/PIM1

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Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

1. Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 2548
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

2. Clinics and Pathology

Disease Diffuse large B-cell lymphoma

3. Genes involved and Proteins

Gene NameBCL6
Location 3q27.3
Gene NamePIM1
Location 6p21.2

4. Bibliography

Mutational and structural analysis of diffuse large B-cell lymphoma using whole-genome sequencing
Morin RD, Mungall K, Pleasance E, Mungall AJ, Goya R, Huff RD, Scott DW, Ding J, Roth A, Chiu R, Corbett RD, Chan FC, Mendez-Lago M, Trinh DL, Bolger-Munro M, Taylor G, Hadj Khodabakhshi A, Ben-Neriah S, Pon J, Meissner B, Woolcock B, Farnoud N, Rogic S, Lim EL, Johnson NA, Shah S, Jones S, Steidl C, Holt R, Birol I, Moore R, Connors JM, Gascoyne RD, Marra MA
Blood 2013 Aug 15;122(7):1256-65
PMID 23699601
 


5. Translocations implicated (Data extracted from papers in the Atlas)

 t(3;6)(q27;p21) BCL6/PIM1

6. External links

BCL6 (3q27.3) PIM1 (6p21.2)

Mitelman databaset(3;6)(q27;p21) [Case List]    t(3;6)(q27;p21) [Transloc-MCList] BCL6/PIM1 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Nov 28 16:20:55 CET 2018

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