t(4;16)(q27;p13) IL2/TNFRSF17

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Written2018-01Jean-Loup Huret, Philippe Dessen

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1. Identity

Atlas_Id 3414
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

2. Clinics and Pathology

Disease Mature T- and NK-cell neoplasm, NOS

3. Genes involved and Proteins

Gene NameIL2
Location 4q27
Gene NameTNFRSF17
Location 16p13.13

4. Bibliography

A new gene, BCM, on chromosome 16 is fused to the interleukin 2 gene by a t(4;16)(q26;p13) translocation in a malignant T cell lymphoma
Laâbi Y, Gras MP, Carbonnel F, Brouet JC, Berger R, Larsen CJ, Tsapis A
EMBO J 1992 Nov;11(11):3897-904
PMID 1396583

5. Translocations implicated (Data extracted from papers in the Atlas)

 t(4;16)(q27;p13) IL2/TNFRSF17

6. External links

IL2 (4q27) TNFRSF17 (16p13.13)

Mitelman databaset(4;16)(q27;p13) [Case List]    t(4;16)(q27;p13) [Transloc-MCList] IL2/TNFRSF17 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
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REVIEW articlesautomatic search in PubMed
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indexed on : Wed Nov 28 16:21:16 CET 2018

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