t(5;6)(q32;q22) CEP85L/PDGFRB

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Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

1. Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 3416
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

2. Clinics and Pathology

Disease Chronic eosinophilic leukemia/hypereosinophilic syndrome

3. Genes involved and Proteins

Gene NameCEP85L
Location 6q22.31
Gene NamePDGFRB
Location 5q32

4. Bibliography

Recurrent CEP85L-PDGFRB fusion in patient with t(5;6) and imatinib-responsive myeloproliferative neoplasm with eosinophilia
Winkelmann N, Hidalgo-Curtis C, Waghorn K, Score J, Dickinson H, Jack A, Ali S, Cross NC
Leuk Lymphoma 2013 Jul;54(7):1527-31
PMID 23186533
 


5. Translocations implicated (Data extracted from papers in the Atlas)

 t(5;6)(q32;q22) CEP85L/PDGFRB

6. External links

CEP85L (6q22.31) PDGFRB (5q32)

Mitelman databaset(5;6)(q32;q22) [Case List]    t(5;6)(q32;q22) [Transloc-MCList] CEP85L/PDGFRB [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
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indexed on : Wed Nov 28 16:21:20 CET 2018

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