t(5;15)(q32;q15) TP53BP1/PDGFRB

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA
Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

1. Identity

Atlas_Id 3428
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

2. Clinics and Pathology

Disease Chronic myeloproliferative disorder, NOS

3. Genes involved and Proteins

Gene NameTP53BP1
Location 15q15.3
Location 5q32

4. Bibliography

p53-Binding protein 1 is fused to the platelet-derived growth factor receptor beta in a patient with a t(5;15)(q33;q22) and an imatinib-responsive eosinophilic myeloproliferative disorder
Grand FH, Burgstaller S, Kühr T, Baxter EJ, Webersinke G, Thaler J, Chase AJ, Cross NC
Cancer Res 2004 Oct 15;64(20):7216-9
PMID 15492236

5. Translocations implicated (Data extracted from papers in the Atlas)

 t(5;15)(q32;q15) TP53BP1/PDGFRB

6. External links

TP53BP1 (15q15.3) PDGFRB (5q32)

Mitelman databaset(5;15)(q32;q15) [Case List]    t(5;15)(q32;q15) [Transloc-MCList] TP53BP1/PDGFRB [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Nov 28 16:21:35 CET 2018

For comments and suggestions or contributions, please contact us atlasgeneticsoncology@usal.es.