t(5;17)(q32;p13) RABEP1/PDGFRB

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Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

1. Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 3430
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

2. Clinics and Pathology

Disease Chronic myelomonocytic leukemia

3. Genes involved and Proteins

Gene NameRABEP1
Location 17p13.2
Gene NamePDGFRB
Location 5q32

4. Bibliography

Rabaptin-5 is a novel fusion partner to platelet-derived growth factor beta receptor in chronic myelomonocytic leukemia
Magnusson MK, Meade KE, Brown KE, Arthur DC, Krueger LA, Barrett AJ, Dunbar CE
Blood 2001 Oct 15;98(8):2518-25
PMID 11588050
 


5. Translocations implicated (Data extracted from papers in the Atlas)

 t(5;17)(q32;p13) RABEP1/PDGFRB

6. External links

RABEP1 (17p13.2) PDGFRB (5q32)

Mitelman databaset(5;17)(q32;p13) [Case List]    t(5;17)(q32;p13) [Transloc-MCList] RABEP1/PDGFRB [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
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indexed on : Wed Nov 28 16:21:37 CET 2018

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