t(6;12)(q22;p13) ETV6/RNF217

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Written2018-01Jean-Loup Huret, Philippe Dessen

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1. Identity

Atlas_Id 2713
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

2. Clinics and Pathology

Disease Acute lymphoblastic leukemia/lymphoblastic lymphoma

3. Genes involved and Proteins

Gene NameETV6
Location 12p13.2
Gene NameRNF217
Location 6q22.31

4. Bibliography

A t(6;12)(q23;p13) results in the fusion of ETV6 to a novel gene, STL, in a B-cell ALL cell line
Suto Y, Sato Y, Smith SD, Rowley JD, Bohlander SK
Genes Chromosomes Cancer 1997 Apr;18(4):254-68
PMID 9087565

5. Translocations implicated (Data extracted from papers in the Atlas)

 t(6;12)(q22;p13) ETV6/RNF217

6. External links

ETV6 (12p13.2) RNF217 (6q22.31)

Mitelman databaset(6;12)(q22;p13) [Case List]    t(6;12)(q22;p13) [Transloc-MCList] ETV6/RNF217 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
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REVIEW articlesautomatic search in PubMed
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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Nov 28 16:21:49 CET 2018

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