t(7;12)(p12;p13) IKZF1/ETV6

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Written	2018-01	Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

1. Identity

ICD-Topo	C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id	2834
Note	Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to How to contribute

2. Clinics and Pathology

Disease

Acute lymphoblastic leukemia/lymphoblastic lymphoma

3. Genes involved and Proteins

Gene Name	IKZF1
Location	7p12.2

Gene Name	ETV6
Location	12p13.2

4. Bibliography

Genomic analyses identify recurrent MEF2D fusions in acute lymphoblastic leukaemia

Gu Z, Churchman M, Roberts K, Li Y, Liu Y, Harvey RC, McCastlain K, Reshmi SC, Payne-Turner D, Iacobucci I, Shao Y, Chen IM, Valentine M, Pei D, Mungall KL, Mungall AJ, Ma Y, Moore R, Marra M, Stonerock E, Gastier-Foster JM, Devidas M, Dai Y, Wood B, Borowitz M, Larsen EE, Maloney K, Mattano LA Jr, Angiolillo A, Salzer WL, Burke MJ, Gianni F, Spinelli O, Radich JP, Minden MD, Moorman AV, Patel B, Fielding AK, Rowe JM, Luger SM, Bhatia R, Aldoss I, Forman SJ, Kohlschmidt J, Mrózek K, Marcucci G, Bloomfield CD, Stock W, Kornblau S, Kantarjian HM, Konopleva M, Paietta E, Willman CL, Loh ML, Hunger SP, Mullighan CG

Nat Commun 2016 Nov 8;7:13331

PMID 27824051

5. Translocations implicated (Data extracted from papers in the Atlas)

t(7;12)(p12;p13) IKZF1/ETV6

6. External links

IKZF1 (7p12.2) ETV6 (12p13.2)

Mitelman database	t(7;12)(p12;p13) [Case List] t(7;12)(p12;p13) [Transloc-MCList] IKZF1/ETV6 [Fusion-MCList]
COSMIC	Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)	[select an item]

REVIEW articles	automatic search in PubMed
Last year articles	automatic search in PubMed
All articles	automatic search in PubMed

indexed on : Wed Nov 28 16:22:06 CET 2018

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