t(8;12)(p11;q15) CPSF6/FGFR1

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Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

1. Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 3441
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

2. Clinics and Pathology

Disease Chronic myeloproliferative disorder, NOS

3. Genes involved and Proteins

Gene NameCPSF6
Location 12q15
Gene NameFGFR1
Location 8p11.23

4. Bibliography

The t(1;9)(p34;q34) and t(8;12)(p11;q15) fuse pre-mRNA processing proteins SFPQ (PSF) and CPSF6 to ABL and FGFR1
Hidalgo-Curtis C, Chase A, Drachenberg M, Roberts MW, Finkelstein JZ, Mould S, Oscier D, Cross NC, Grand FH
Genes Chromosomes Cancer 2008 May;47(5):379-85
PMID 18205209
 


5. Translocations implicated (Data extracted from papers in the Atlas)

 t(8;12)(p11;q15) CPSF6/FGFR1

6. External links

CPSF6 (12q15) FGFR1 (8p11.23)

Mitelman databaset(8;12)(p11;q15) [Case List]    t(8;12)(p11;q15) [Transloc-MCList] CPSF6/FGFR1 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
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indexed on : Wed Nov 28 16:22:19 CET 2018

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