t(8;12)(q22;p13) ETV6/STK3

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Written2018-01Jean-Loup Huret, Philippe Dessen

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1. Identity

Atlas_Id 2715
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

2. Clinics and Pathology

Disease Acute myeloblastic leukemia with minimal differentiation (FAB type M0)

3. Genes involved and Proteins

Gene NameETV6
Location 12p13.2
Gene NameSTK3
Location 8q22.2

4. Bibliography

Identification of a fusion gene composed of a Hippo pathway gene MST2 and a common translocation partner ETV6 in a recurrent translocation t(8;12)(q22;p13) in acute myeloid leukemia
Ogawa S, Yokoyama Y, Suzukawa K, Nanmoku T, Kurita N, Seki M, Maie K, Suyama T, Takaiwa N, Sakata-Yanagimoto M, Obara N, Hasegawa Y, Chiba S
Ann Hematol 2015 Aug;94(8):1431-3
PMID 25933678

5. Translocations implicated (Data extracted from papers in the Atlas)

 t(8;12)(q22;p13) ETV6/STK3

6. External links

ETV6 (12p13.2) STK3 (8q22.2)

Mitelman databaset(8;12)(q22;p13) [Case List]    t(8;12)(q22;p13) [Transloc-MCList] ETV6/STK3 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
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REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Nov 28 16:22:20 CET 2018

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