t(8;19)(q24;q13) BCL3/MYC

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Written2018-01Jean-Loup Huret, Philippe Dessen

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1. Identity

Atlas_Id 2541
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

2. Clinics and Pathology

Disease B-prolymphocytic leukemia

3. Genes involved and Proteins

Gene NameBCL3
Location 19q13.32
Gene NameMYC
Location 8q24.21

4. Bibliography

Activation of MYC in a masked t(8;17) translocation results in an aggressive B-cell leukemia
Gauwerky CE, Huebner K, Isobe M, Nowell PC, Croce CM
Proc Natl Acad Sci U S A 1989 Nov;86(22):8867-71
PMID 2682663

5. Translocations implicated (Data extracted from papers in the Atlas)

 t(8;19)(q24;q13) BCL3/MYC

6. External links

BCL3 (19q13.32) MYC (8q24.21)

Mitelman databaset(8;19)(q24;q13) [Case List]    t(8;19)(q24;q13) [Transloc-MCList] BCL3/MYC [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed

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indexed on : Wed Nov 28 16:22:23 CET 2018

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