t(X;21)(q25;q22) ELF4/ERG

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA
Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

1. Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 3462
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

2. Clinics and Pathology

Disease Acute myeloid leukemia, NOS

3. Genes involved and Proteins

Gene NameELF4
Location Xq26.1
Gene NameERG
Location 21q22.2

4. Bibliography

ELF4 is fused to ERG in a case of acute myeloid leukemia with a t(X;21)(q25-26;q22)
Moore SD, Offor O, Ferry JA, Amrein PC, Morton CC, Dal Cin P
Leuk Res 2006 Aug;30(8):1037-42
PMID 16303180
 


5. Translocations implicated (Data extracted from papers in the Atlas)

 t(X;21)(q25;q22) ELF4/ERG

6. External links

ELF4 (Xq26.1) ERG (21q22.2)

Mitelman databaset(X;21)(q25;q22) [Case List]    t(X;21)(q25;q22) [Transloc-MCList] ELF4/ERG [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
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indexed on : Wed Nov 28 16:22:49 CET 2018

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