t(11;12)(q12;p13) ETV6/LPXN

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Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

1. Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 2707
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

2. Clinics and Pathology

Disease Acute myeloblastic leukemia with maturation (FAB type M2)

3. Genes involved and Proteins

Gene NameETV6
Location 12p13.2
Gene NameLPXN
Location 11q12.1

4. Bibliography

ETV6-LPXN fusion transcript generated by t(11;12)(q12
Abe A, Yamamoto Y, Iba S, Kanie T, Okamoto A, Tokuda M, Inaguma Y, Yanada M, Morishima S, Mizuta S, Akatsuka Y, Okamoto M, Kameyama T, Mayeda A, Emi N
1;p13) in a patient with relapsing acute myeloid leukemia with NUP98-HOXA9 Genes Chromosomes Cancer
PMID 26542893
 


5. Translocations implicated (Data extracted from papers in the Atlas)

 t(11;12)(q12;p13) ETV6/LPXN

6. External links

ETV6 (12p13.2) LPXN (11q12.1)

Mitelman databaset(11;12)(q12;p13) [Case List]    t(11;12)(q12;p13) [Transloc-MCList] ETV6/LPXN [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Nov 28 16:23:13 CET 2018

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