t(11;22)(q24;q12) EWSR1/FLI1

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Written2018-01Jean-Loup Huret, Philippe Dessen

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1. Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 2716
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

2. Clinics and Pathology

Disease Ewing sarcoma

3. Genes involved and Proteins

Gene NameEWSR1
Location 22q12.2
Gene NameFLI1
Location 11q24.3

4. Bibliography

Association of EWS-FLI1 type 1 fusion with lower proliferative rate in Ewing's sarcoma
de Alava E, Panizo A, Antonescu CR, Huvos AG, Pardo-Mindán FJ, Barr FG, Ladanyi M
Am J Pathol 2000 Mar;156(3):849-55
PMID 10702401
 


5. Translocations implicated (Data extracted from papers in the Atlas)

 t(11;22)(q24;q12) EWSR1/FLI1

6. External links

EWSR1 (22q12.2) FLI1 (11q24.3)

Mitelman databaset(11;22)(q24;q12) [Case List]    t(11;22)(q24;q12) [Transloc-MCList] EWSR1/FLI1 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
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indexed on : Wed Nov 28 16:23:28 CET 2018

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