t(12;12)(p12;p13) ETV6/PTPRO

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Written	2018-01	Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

1. Identity

ICD-Topo	C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id	2711
Note	Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to How to contribute

2. Clinics and Pathology

Disease

Acute lymphoblastic leukemia/lymphoblastic lymphoma

3. Genes involved and Proteins

Gene Name	ETV6
Location	12p13.2

Gene Name	PTPRO
Location	12p12.3

4. Bibliography

Identification of ETV6-RUNX1-like and DUX4-rearranged subtypes in paediatric B-cell precursor acute lymphoblastic leukaemia

Lilljebjörn H, Henningsson R, Hyrenius-Wittsten A, Olsson L, Orsmark-Pietras C, von Palffy S, Askmyr M, Rissler M, Schrappe M, Cario G, Castor A, Pronk CJ, Behrendtz M, Mitelman F, Johansson B, Paulsson K, Andersson AK, Fontes M, Fioretos T

Nat Commun 2016 Jun 6;7:11790

PMID 27265895

5. Translocations implicated (Data extracted from papers in the Atlas)

t(12;12)(p12;p13) ETV6/PTPRO

6. External links

ETV6 (12p13.2) PTPRO (12p12.3)

Mitelman database	t(12;12)(p12;p13) [Case List] t(12;12)(p12;p13) [Transloc-MCList] ETV6/PTPRO [Fusion-MCList]
COSMIC	Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)	[select an item]

REVIEW articles	automatic search in PubMed
Last year articles	automatic search in PubMed
All articles	automatic search in PubMed

indexed on : Wed Nov 28 16:23:28 CET 2018

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