t(12;13)(p13;q12) FLT3/ETV6

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Written2018-01Jean-Loup Huret, Philippe Dessen

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1. Identity

Atlas_Id 2730
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

2. Clinics and Pathology

Disease Acute myelomonocytic leukemia (FAB type M4)

3. Genes involved and Proteins

Gene NameFLT3
Location 13q12.2
Gene NameETV6
Location 12p13.2

4. Bibliography

Double-hit of FLT3 gene in a fatal case of acute myemonocytic leukaemia
Lu G, Schulz RA, Bueso-Ramos CE, Cortes JE, Iris Wang X, Medeiros LJ, Yin CC
J Clin Pathol 2013 Sep;66(9):826-9
PMID 23703854

5. Translocations implicated (Data extracted from papers in the Atlas)

 t(12;13)(p13;q12) FLT3/ETV6

6. External links

FLT3 (13q12.2) ETV6 (12p13.2)

Mitelman databaset(12;13)(p13;q12) [Case List]    t(12;13)(p13;q12) [Transloc-MCList] FLT3/ETV6 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
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REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Nov 28 16:23:32 CET 2018

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