t(15;17)(q22;q21) RARA/PML

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA
Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

1. Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 3136
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

2. Clinics and Pathology

Disease Acute myeloid leukemia, NOS

3. Genes involved and Proteins

Gene NameRARA
Location 17q21.2
Gene NamePML
Location 15q24.1

4. Bibliography

The landscape and therapeutic relevance of cancer-associated transcript fusions
Yoshihara K, Wang Q, Torres-Garcia W, Zheng S, Vegesna R, Kim H, Verhaak RG
Oncogene 2015 Sep 10;34(37):4845-54
PMID 25500544
 


5. Translocations implicated (Data extracted from papers in the Atlas)

 t(15;17)(q22;q21) RARA/PML

6. External links

RARA (17q21.2) PML (15q24.1)

Mitelman databaset(15;17)(q22;q21) [Case List]    t(15;17)(q22;q21) [Transloc-MCList] RARA/PML [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed


© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Nov 28 16:24:00 CET 2018

For comments and suggestions or contributions, please contact us atlasgeneticsoncology@usal.es.