t(15;21)(q26;q22) RUNX1/SV2B

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA
Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

1. Identity

Atlas_Id 3180
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

2. Clinics and Pathology

Disease Acute lymphoblastic leukemia/lymphoblastic lymphoma

3. Genes involved and Proteins

Gene NameRUNX1
Location 21q22.12
Gene NameSV2B
Location 15q26.1

4. Bibliography

Identification of a novel fusion gene involving RUNX1 and the antisense strand of SV2B in a BCR-ABL1-positive acute leukemia
Giguère A, Hébert J
Genes Chromosomes Cancer 2013 Dec;52(12):1114-22
PMID 24123676

5. Translocations implicated (Data extracted from papers in the Atlas)

 t(15;21)(q26;q22) RUNX1/SV2B

6. External links

RUNX1 (21q22.12) SV2B (15q26.1)

Mitelman databaset(15;21)(q26;q22) [Case List]    t(15;21)(q26;q22) [Transloc-MCList] RUNX1/SV2B [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Nov 28 16:24:02 CET 2018

For comments and suggestions or contributions, please contact us atlasgeneticsoncology@usal.es.