t(17;19)(q22;q13) MPO/ZNF296

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Written2018-01Jean-Loup Huret, Philippe Dessen

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1. Identity

Atlas_Id 1578
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

2. Clinics and Pathology

Disease Acute myeloblastic leukemia without maturation (FAB type M1)

3. Genes involved and Proteins

Gene NameMPO
Location 17q22
Gene NameZNF296
Location 19q13.32

4. Bibliography

Overexpression of ZNF342 by juxtaposition with MPO promoter/enhancer in the novel translocation t(17;19)(q23;q13
Poland KS, Shardy DL, Azim M, Naeem R, Krance RA, Dreyer ZE, Neeley ES, Zhang N, Qiu YH, Kornblau SM, Plon SE
32) in pediatric acute myeloid leukemia and analysis of ZNF342 expression in leukemia Genes Chromosomes Cancer
PMID 19255975

5. Translocations implicated (Data extracted from papers in the Atlas)

 t(17;19)(q22;q13) MPO/ZNF296

6. External links

MPO (17q22) ZNF296 (19q13.32)

Mitelman databaset(17;19)(q22;q13) [Case List]    t(17;19)(q22;q13) [Transloc-MCList] MPO/ZNF296 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed

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indexed on : Wed Nov 28 16:24:14 CET 2018

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