t(17;22)(q21;q13) COL1A1/PDGFB

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Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

1. Identity

Atlas_Id 2618
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

2. Clinics and Pathology

Disease Dermatofibrosarcoma protuberans/Bednar tumor/giant cell fibroblastoma

3. Genes involved and Proteins

Gene NameCOL1A1
Location 17q21.33
Gene NamePDGFB
Location 22q13.1

4. Bibliography

No correlation between the molecular subtype of COL1A1-PDGFB fusion gene and the clinico-histopathological features of dermatofibrosarcoma protuberans
Giacchero D, Maire G, Nuin PA, Berthier F, Ebran N, Carlotti A, Celerier P, Coindre JM, Esteve E, Fraitag S, Guillot B, Ranchere-Vince D, Saiag P, Terrier P, Lacour JP, Pedeutour F
J Invest Dermatol 2010 Mar;130(3):904-7
PMID 19890351

5. Translocations implicated (Data extracted from papers in the Atlas)

 t(17;22)(q21;q13) COL1A1/PDGFB

6. External links

COL1A1 (17q21.33) PDGFB (22q13.1)

Mitelman databaset(17;22)(q21;q13) [Case List]    t(17;22)(q21;q13) [Transloc-MCList] COL1A1/PDGFB [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
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REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Nov 28 16:24:16 CET 2018

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