t(19;22)(q13;q11) IGL/BCL3

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Written2018-01Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

1. Identity

ICD-Topo C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS
Atlas_Id 3493
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

2. Clinics and Pathology

Disease Follicular lymphoma

3. Genes involved and Proteins

Gene NameIGL
Location 22q11.22
Gene NameBCL3
Location 19q13.32

4. Bibliography

A comprehensive genetic and histopathologic analysis identifies two subgroups of B-cell malignancies carrying a t(14;19)(q32;q13) or variant BCL3-translocation
Martín-Subero JI, Ibbotson R, Klapper W, Michaux L, Callet-Bauchu E, Berger F, Calasanz MJ, De Wolf-Peeters C, Dyer MJ, Felman P, Gardiner A, Gascoyne RD, Gesk S, Harder L, Horsman DE, Kneba M, Küppers R, Majid A, Parry-Jones N, Ritgen M, Salido M, Solé F, Thiel G, Wacker HH, Oscier D, Wlodarska I, Siebert R
Leukemia 2007 Jul;21(7):1532-44
PMID 17495977
 


5. Translocations implicated (Data extracted from papers in the Atlas)

 t(19;22)(q13;q11) IGL/BCL3

6. External links

IGL (22q11.22) BCL3 (19q13.32)

Mitelman databaset(19;22)(q13;q11) [Case List]    t(19;22)(q13;q11) [Transloc-MCList] IGL/BCL3 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
 
 
REVIEW articlesautomatic search in PubMed
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indexed on : Wed Nov 28 16:24:23 CET 2018

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