Chromosome 14

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ENTITIES: by Chromosome band

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22

Chromosome 14

[previous]   14 14p 14q 14p13 14p12 14p11 14q11 14q12 14q13 14q21 14q22 14q23 14q24 14q31 14q32   [next]

Band 14p11

chr14:8000000-17200000 (9200 Kb)

  • Chromosomal abnormalities in band 14p11
  • Genes in band 14p11 (reference hg38)
  • External links
  • References

    Chromosomal abnormalities in band 14p11

    (click on headers to reorder columns)
    Band 1Band 2ClassEntityPartner 1Partner 2LinksTopographyMorphology[PubMed][Study]
    14p1114q21Cosmic_SVdel(14)(p11q21)  Cosmic_SV [COST196143]prostate__NScarcinoma__adenocarcinoma[PubMed] 
    14p1114q21Cosmic_SVdel(14)(p11q21)  Cosmic_SV [COST196753]prostate__NScarcinoma__adenocarcinoma[PubMed] 
    14p1114q31Cosmic_SVdel(14)(p11q31)  Cosmic_SV [COST198387]prostate__NScarcinoma__adenocarcinoma[PubMed] 
    14p1114q32Cosmic_SVdel(14)(p11q32)  Cosmic_SV [COST195698]prostate__NScarcinoma__adenocarcinoma[PubMed] 
    14p11 Mitelmander(14)add(14)(p11)add(14)(q32)  Mitelman (CGAP)Soft tissueLeiomyosarcoma  
    1q1014p11Mitelmander(14)t(1;14)(q10;p11)  Mitelman (CGAP) Multiple myeloma  
    1q1114p11Mitelmander(14)t(1;14)(q11;p11)  Mitelman (CGAP) Polycythemia vera  
    1q2114p11Mitelmander(14)t(1;14)(q21;p11)  Mitelman (CGAP) Acute lymphoblastic leukemia/lymphoblastic lymphoma  
    14p1117q11Mitelmander(14)t(14;17)(p11;q11)  Mitelman (CGAP) Chronic lymphocytic leukemia  
    14p11 Cosmic_SVdup(14)(p11)  Cosmic_SV [COST195943]prostate__NScarcinoma__adenocarcinoma[PubMed] 
    14p11 Cosmic_SVdup(14)(p11)  Cosmic_SV [COST196314]prostate__NScarcinoma__adenocarcinoma[PubMed] 
    14p11 Cosmic_SVdup(14)(p11)  Cosmic_SV [COST196382]prostate__NScarcinoma__adenocarcinoma[PubMed] 
    14p11 Cosmic_SVdup(14)(p11)  Cosmic_SV [COST199342]prostate__NScarcinoma__adenocarcinoma[PubMed] 
    14p1114q31Cosmic_SVinv(14)(p11q31)  Cosmic_SV [COST198832]prostate__NScarcinoma__adenocarcinoma[PubMed] 
    11q1314p11Mitelmant(11;14)(q13;p11)  Mitelman (CGAP) Acute lymphoblastic leukemia/lymphoblastic lymphoma  
    1q1014p11dbCRIDt(1;14)(q10;p11.2)  11481Multiple Myeloma[PubMed] 
    1q1014p11Mitelmant(1;14)(q10;p11)  Mitelman (CGAP) Multiple myeloma  
    1q1114p11Mitelmant(1;14)(q11;p11)  Mitelman (CGAP) Polycythemia vera  
    1q2114p11Mitelmant(1;14)(q21;p11)  Mitelman (CGAP) Acute lymphoblastic leukemia/lymphoblastic lymphoma  
    14p1115q11Mitelmant(14;15)(p11;q11)  Mitelman (CGAP)BreastAdenocarcinoma  
    14p1117p11Mitelmant(14;17)(p11;p11)  Mitelman (CGAP) Chronic myeloid leukemia, t(9;22)  
    14p1117q11Mitelmant(14;17)(p11;q11)  Mitelman (CGAP) Chronic lymphocytic leukemia  
    14p1121q11dbCRIDt(14;21)(p11;q11)  10053T-Cell Prolymphocytic Leukemia[PubMed] 
    14p1121q21dbCRIDt(14;21)(p11;q21)  10133Down Syndrome[PubMed] 
    14p1121q21dbCRIDt(14;21)(p11;q21)  10134Down Syndrome[PubMed] 
    14p1121q21dbCRIDt(14;21)(p11;q21)  10135Down Syndrome[PubMed] 
    14p1121q21dbCRIDt(14;21)(p11;q21)  10136Down Syndrome[PubMed] 
    14p1121q21dbCRIDt(14;21)(p11;q21)  10137Down Syndrome[PubMed] 
    Yq1214p11dbCRIDt(Y;14)(q12;p11)  10378Infertility[PubMed] 

    Genes in band 14p11

    (click on headers to reorder columns)
    GoldenPath hg38Band 1Band 2ClassCloneFusionPartner 1Partner 2LinksTopographyMorphologyPubmedOmimAccession

    [ Bold normal : A; Italic normal :G; Italic small : E ]

    X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 [previous]   14 14p 14q 14p13 14p12 14p11 14q11 14q12 14q13 14q21 14q22 14q23 14q24 14q31 14q32   [next]

    External links

    Mitelman Database [NCI] : Breakpoint 14p11

    [ UCSC ][ enSembl ][ MapView - NCBI ][ 1000Genomes ][ EVS ][ CGWB ][ DGV ][ DBVar ][ OMIM ][ HapMap ][ DECIPHER ] [ ECARUCA ]
    Gene Expression (MSigDB) in 14p11  [ HTC ]  [ NCI ]  [ INV ]

    Global tables

  • Anomalies list (tabulated txt file)
  • Gene list (tabulated txt file)
  • list of gene fusions for each gene (with origins of the data)
  • list of gene fusions by origin (with topography and morphology)
  • References

  • [L] Fusion gene microarray reveals cancer type-specificity among fusion genes. Lovf M et al.Genes Chromosomes Cancer. 2011 May;50(5):348-57.   [PubMed 2011]
  • [S] A universal assay for detection of oncogenic fusion transcripts by oligo microarray analysis. Skotheim RI, et al. Mol Cancer. 2009 Jan 19;8:5.  [PubMed 21009]
  • [V] ETV6 fusion genes in hematological malignancies: A review. De Braekeleer E. et al. Leuk Res. 2012 May 12.   [PubMed 2012]
  • [GT] Cell Lines (Genentech)  [Pubmed 2015]   Nature Biotech Suppl.Table8
  • [FC] Fusion cancer (Beijing) [PubMed 2015] (the fusions are limited to class A and B)
  • [NOR] [PubMed 2016] Babiceanu M et al. Recurrent chimeric fusion RNAs in non-cancer tissues and cells. Nucleic Acids Res. 2016 Feb 2 (Table S3)
  • [URK][PubMed 2016] Urakami et al. Next generation sequencing approach for detecting 491 fusion genes from human cancer. Biomed Res. 2016;37(1):51-62.
  • [AM] [PubMed 2016] Global analysis of somatic structural genomic alterations and their impact on gene expression in diverse human cancersAlaei-Mahabadi B. et al.,Proc Natl Acad Sci U S A. 2016 Nov 16. pii: 201606220.
  • [FM] [PubMed 2018] Genomic hotspots but few recurrent fusion genes in breast cancer, Fimereli et al., Genes Chromosomes Cancer. (SupplTableS2.xls) 2018 Feb 13
  • [MA] [PubMed 2018] Pan-cancer genome and transcriptome analyses of1,699 paediatric leukaemias and solid tumours, Ma et al, Nature (March 2018) Table S3
  • [GAO] [PubMed 2018] Driver Fusions and Their Implications in the Development and Treatment of Human Cancers. Gao et al, Cell Reports (April 2018) Table S2
  • [MAY] [PubMed 2018] Development and Verification of an RNA Sequencing (RNA-Seq) Assay for the Detection of Gene Fusions in Tumor, Winters et al (July 2018) Table S7
  • FusionGDB: fusion gene annotation DataBase. Kim P t Zhou X. Nucleic Acids Res. 2019 Jan 8;47(D1):D994-D1004.[PubMed]site FusionGDB


    Writtenmay 2012Philippe Dessen
    Updatedjanv. 2019Philippe Dessen and Jean-Loup Huret


    This paper should be referenced as such :
    Dessen P and Huret JL. Chromosomal band 14p11. Atlas Genet Cytogenet Oncol Haematol. July 2012.
    URL :
    © Atlas of Genetics and Cytogenetics in Oncology and Haematology
    indexed on : mar. janv. 22 11:52:28 CET 2019

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