Chromosome 1


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ENTITIES: by Chromosome band

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Chromosome 1


[previous]   1 1p 1q 1p36 1p35 1p34 1p33 1p32 1p31 1p22 1p21 1p13 1p12 1p11 1q11 1q12 1q21 1q22 1q23 1q24 1q25 1q31 1q32 1q41 1q42 1q43 1q44   [next]

Band 1q11

chr1:123400000-125100000 (1700 Kb)

  • Chromosomal abnormalities in band 1q11
  • Genes in band 1q11 (reference hg38)
  • External links
  • References

    Chromosomal abnormalities in band 1q11

    (click on headers to reorder columns)
    Band 1Band 2ClassEntityPartner 1Partner 2LinksTopographyMorphology[PubMed][Study]
    1q11 Mitelmandel(1)(q11)  Mitelman (CGAP) Acute erythroleukemia (FAB type M6)  
    1q11 Mitelmandel(1)(q11)  Mitelman (CGAP) Acute lymphoblastic leukemia/lymphoblastic lymphoma  
    1q11 Mitelmandel(1)(q11)  Mitelman (CGAP) Acute myeloblastic leukemia with maturation (FAB type M2)  
    1q11 Mitelmandel(1)(q11)  Mitelman (CGAP) Acute myeloid leukemia, NOS  
    1q11 Mitelmandel(1)(q11)  Mitelman (CGAP)BrainAstrocytoma, grade III-IV/Glioblastoma  
    1q11 Mitelmandel(1)(q11)  Mitelman (CGAP)BrainMeningioma  
    1q11 Mitelmandel(1)(q11)  Mitelman (CGAP)BreastAdenocarcinoma  
    1q11 Mitelmandel(1)(q11)  Mitelman (CGAP) Burkitt lymphoma/leukemia  
    1q11 Mitelmandel(1)(q11)  Mitelman (CGAP) Chronic myeloid leukemia, t(9;22)  
    1q11 Mitelmandel(1)(q11)  Mitelman (CGAP) Diffuse large B-cell lymphoma  
    1q11 Mitelmandel(1)(q11)  Mitelman (CGAP) Follicular lymphoma  
    1q11 Mitelmandel(1)(q11)  Mitelman (CGAP)KidneyAdenocarcinoma  
    1q11 Mitelmandel(1)(q11)  Mitelman (CGAP)Large intestineAdenocarcinoma  
    1q11 Mitelmandel(1)(q11)  Mitelman (CGAP)LarynxSquamous cell carcinoma  
    1q11 Mitelmandel(1)(q11)  Mitelman (CGAP)LungAdenocarcinoma  
    1q11 Mitelmandel(1)(q11)  Mitelman (CGAP)LungSquamous cell carcinoma  
    1q11 Mitelmandel(1)(q11)  Mitelman (CGAP) Multiple myeloma  
    1q11 Mitelmandel(1)(q11)  Mitelman (CGAP) Mycosis fungoides/Szary syndrome  
    1q11 Mitelmandel(1)(q11)  Mitelman (CGAP)Oral cavitySquamous cell carcinoma  
    1q11 Mitelmandel(1)(q11)  Mitelman (CGAP)Oro- and hypopharynxSquamous cell carcinoma  
    1q11 Mitelmandel(1)(q11)  Mitelman (CGAP)OvaryAdenocarcinoma  
    1q11 Mitelmandel(1)(q11)  Mitelman (CGAP)PancreasAdenocarcinoma  
    1q11 Mitelmandel(1)(q11)  Mitelman (CGAP)PleuraMesothelioma  
    1q11 Mitelmandel(1)(q11)  Mitelman (CGAP) Refractory anemia with excess of blasts (FAB)  
    1q11 Mitelmandel(1)(q11)  Mitelman (CGAP)SkeletonOsteosarcoma, NOS  
    1q11 Mitelmandel(1)(q11)  Mitelman (CGAP)SkinMalignant melanoma  
    1q11 Mitelmandel(1)(q11)  Mitelman (CGAP)Soft tissueLeiomyosarcoma  
    1q11 Mitelmandel(1)(q11)  Mitelman (CGAP)Soft tissueMyogenic sarcoma, NOS  
    1q11 Mitelmandel(1)(q11)  Mitelman (CGAP)Soft tissueMyxofibrosarcoma  
    1q11 Mitelmandel(1)(q11)  Mitelman (CGAP)Soft tissueUndifferentiated pleomorphic sarcoma  
    1q11 Mitelmandel(1)(q11)  Mitelman (CGAP)TestisTeratoma (mature and immature)  
    1q11 Mitelmandel(1)(q11)  Mitelman (CGAP)TongueSquamous cell carcinoma  
    1q11 Mitelmandel(1)(q11)  Mitelman (CGAP)Uterus, corpusEndometrial stromal sarcoma  
    1q11 Mitelmandel(1)(q11)  Mitelman (CGAP)Uterus, corpusMetaplastic carcinoma  
    1q1112p11Mitelmander(12)t(1;12)(q11;p11)  Mitelman (CGAP) Acute monoblastic leukemia (FAB type M5)  
    1q1112q24Mitelmander(12)t(1;12)(q11;q24)  Mitelman (CGAP) Multiple myeloma  
    1q1113p13Mitelmander(13)t(1;13)(q11;p13)  Mitelman (CGAP)EyeMalignant melanoma  
    1q1114p11Mitelmander(14)t(1;14)(q11;p11)  Mitelman (CGAP) Polycythemia vera  
    1q1115p11Mitelmander(15)t(1;15)(q11;p11)  Mitelman (CGAP) Acute lymphoblastic leukemia/lymphoblastic lymphoma  
    1q1115p11Mitelmander(15)t(1;15)(q11;p11)  Mitelman (CGAP) Follicular lymphoma  
    1q1115p11Mitelmander(15)t(1;15)(q11;p11)  Mitelman (CGAP) Refractory anemia  
    1q1115p13Mitelmander(15)t(1;15)(q11;p13)  Mitelman (CGAP)EyeMalignant melanoma  
    1q1116p13Mitelmander(16)t(1;16)(q11;p13)  Mitelman (CGAP) Multiple myeloma  
    1q1116q11Mitelmander(16)t(1;16)(q11;q11)  Mitelman (CGAP) Multiple myeloma  
    1q1116q11Mitelmander(16)t(1;16)(q11;q11)  Mitelman (CGAP)SkeletonEwing sarcoma  
    1q1117p13Mitelmander(17)t(1;17)(q11;p13)  Mitelman (CGAP) Acute lymphoblastic leukemia/lymphoblastic lymphoma  
    1q1119p13Mitelmander(19)t(1;19)(q11;p13)  Mitelman (CGAP) Acute erythroleukemia (FAB type M6)  
    1q1119p13Mitelmander(19)t(1;19)(q11;p13)  Mitelman (CGAP) Acute lymphoblastic leukemia/lymphoblastic lymphoma  
    1q1119q13Mitelmander(19)t(1;19)(q11;q13)  Mitelman (CGAP) Multiple myeloma  
    1p361q11Mitelmander(1)t(1;1)(p36;q11)  Mitelman (CGAP) Follicular lymphoma  
    1p361q11Mitelmander(1)t(1;1)(p36;q11)  Mitelman (CGAP)KidneyWilms tumor  
    1q1121p11Mitelmander(21)t(1;21)(q11;p11)  Mitelman (CGAP) Acute lymphoblastic leukemia/lymphoblastic lymphoma  
    1q1121q22Mitelmander(21)t(1;21)(q11;q22)  Mitelman (CGAP) Acute lymphoblastic leukemia/lymphoblastic lymphoma  
    1q1121q22Mitelmander(21)t(1;21)(q11;q22)  Mitelman (CGAP) Multiple myeloma  
    1q1122p11Mitelmander(22)t(1;22)(q11;p11)  Mitelman (CGAP) Acute lymphoblastic leukemia/lymphoblastic lymphoma  
    1q114q35Mitelmander(4)t(1;4)(q11;q35)  Mitelman (CGAP) Multiple myeloma  
    1q116q11Mitelmander(6)t(1;6)(q11;q11)  Mitelman (CGAP)Unknown siteMalignant melanoma  
    1q117p11Mitelmander(7)t(1;7)(q11;p11)  Mitelman (CGAP)BrainMeningioma  
    1q118p23Mitelmander(8)t(1;8)(q11;p23)  Mitelman (CGAP) Multiple myeloma  
    1q119p11Mitelmander(9)t(1;9)(q11;p11)  Mitelman (CGAP) Acute lymphoblastic leukemia/lymphoblastic lymphoma  
    1q111q21Mitelmandup(1)(q11q21)  Mitelman (CGAP) Chronic myeloid leukemia, t(9;22)  
    1q111q25Mitelmandup(1)(q11q25)  Mitelman (CGAP) Multiple myeloma  
    1q111q32Mitelmandup(1)(q11q32)  Mitelman (CGAP) Multiple myeloma  
    1q111q44Mitelmandup(1)(q11q44)  Mitelman (CGAP) Acute lymphoblastic leukemia/lymphoblastic lymphoma  
    1q111q44Mitelmandup(1)(q11q44)  Mitelman (CGAP) Burkitt lymphoma/leukemia  
    1q11 Mitelmani(1)(q11)  Mitelman (CGAP) Acute myeloid leukemia, NOS  
    1q1111p15dbCRIDt(1;11)(q11;p15)  10813Myelodysplasia Syndrome[PubMed] 
    1q1112p11Mitelmant(1;12)(q11;p11)  Mitelman (CGAP) Acute monoblastic leukemia (FAB type M5)  
    1q1112q24Mitelmant(1;12)(q11;q24)  Mitelman (CGAP) Multiple myeloma  
    1q1113p13Mitelmant(1;13)(q11;p13)  Mitelman (CGAP)EyeMalignant melanoma  
    1q1114p11Mitelmant(1;14)(q11;p11)  Mitelman (CGAP) Polycythemia vera  
    1q1115p11Mitelmant(1;15)(q11;p11)  Mitelman (CGAP) Acute lymphoblastic leukemia/lymphoblastic lymphoma  
    1q1115p11Mitelmant(1;15)(q11;p11)  Mitelman (CGAP) Follicular lymphoma  
    1q1115p11Mitelmant(1;15)(q11;p11)  Mitelman (CGAP) Refractory anemia  
    1q1115p13Mitelmant(1;15)(q11;p13)  Mitelman (CGAP)EyeMalignant melanoma  
    1q1116p13Mitelmant(1;16)(q11;p13)  Mitelman (CGAP) Multiple myeloma  
    1q1116q11Mitelmant(1;16)(q11;q11)  Mitelman (CGAP) Multiple myeloma  
    1q1116q11Mitelmant(1;16)(q11;q11)  Mitelman (CGAP)SkeletonEwing sarcoma  
    1q1117p13Mitelmant(1;17)(q11;p13)  Mitelman (CGAP) Acute lymphoblastic leukemia/lymphoblastic lymphoma  
    1q1119p13Mitelmant(1;19)(q11;p13)  Mitelman (CGAP) Acute erythroleukemia (FAB type M6)  
    1q1119p13Mitelmant(1;19)(q11;p13)  Mitelman (CGAP) Acute lymphoblastic leukemia/lymphoblastic lymphoma  
    1q1119q13Mitelmant(1;19)(q11;q13)  Mitelman (CGAP) Multiple myeloma  
    1p361q11Mitelmant(1;1)(p36;q11)  Mitelman (CGAP) Follicular lymphoma  
    1p361q11Mitelmant(1;1)(p36;q11)  Mitelman (CGAP)KidneyWilms tumor  
    1q1120q11dbCRIDt(1;20)(q11;q11.1)  10434Multiple Myeloma[PubMed] 
    1q1121p11dbCRIDt(1;21)(q11;p11)  11483Multiple Myeloma[PubMed] 
    1q1121p11Mitelmant(1;21)(q11;p11)  Mitelman (CGAP) Acute lymphoblastic leukemia/lymphoblastic lymphoma  
    1q1121q22Mitelmant(1;21)(q11;q22)  Mitelman (CGAP) Acute lymphoblastic leukemia/lymphoblastic lymphoma  
    1q1121q22Mitelmant(1;21)(q11;q22)  Mitelman (CGAP) Multiple myeloma  
    1q1122p11Mitelmant(1;22)(q11;p11)  Mitelman (CGAP) Acute lymphoblastic leukemia/lymphoblastic lymphoma  
    1q114q35dbCRIDt(1;4)(q11;q35)  11482Multiple Myeloma[PubMed] 
    1q114q35Mitelmant(1;4)(q11;q35)  Mitelman (CGAP) Multiple myeloma  
    1q116q11Mitelmant(1;6)(q11;q11)  Mitelman (CGAP)SkinMalignant melanoma  
    1q116q11Mitelmant(1;6)(q11;q11)  Mitelman (CGAP)Unknown siteMalignant melanoma  
    1q117p11Mitelmant(1;7)(q11;p11)  Mitelman (CGAP)BrainMeningioma  
    1q117q31dbCRIDt(1;7)(q11;q31)  11188Acute Myelocytic Leukemia[PubMed] 
    1q118p23Mitelmant(1;8)(q11;p23)  Mitelman (CGAP) Multiple myeloma  
    1q119p11Mitelmant(1;9)(q11;p11)  Mitelman (CGAP) Acute lymphoblastic leukemia/lymphoblastic lymphoma  
    Xq131q11dbCRIDt(X;1)(q13.1;q11)  11039Ovarian Cancer[PubMed] 

    Genes in band 1q11

    (click on headers to reorder columns)
    GoldenPath hg38Band 1Band 2ClassCloneFusionPartner 1Partner 2LinksTopographyMorphologyPubmedOmimAccession

    [ Bold normal : A; Italic normal :G; Italic small : E ]

    X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 [previous]   1 1p 1q 1p36 1p35 1p34 1p33 1p32 1p31 1p22 1p21 1p13 1p12 1p11 1q11 1q12 1q21 1q22 1q23 1q24 1q25 1q31 1q32 1q41 1q42 1q43 1q44   [next]

    External links

    Mitelman Database [NCI] : Breakpoint 1q11

    [ UCSC ][ enSembl ][ MapView - NCBI ][ 1000Genomes ][ EVS ][ CGWB ][ DGV ][ DBVar ][ OMIM ][ HapMap ][ DECIPHER ] [ ECARUCA ]
    Gene Expression (MSigDB) in 1q11  [ HTC ]  [ NCI ]  [ INV ]

    Global tables

  • Anomalies list (tabulated txt file)
  • Gene list (tabulated txt file)
  • list of gene fusions for each gene (with origins of the data)
  • list of gene fusions by origin (with topography and morphology)
  • References

  • [L] Fusion gene microarray reveals cancer type-specificity among fusion genes. Lovf M et al.Genes Chromosomes Cancer. 2011 May;50(5):348-57.   [PubMed 2011]
  • [S] A universal assay for detection of oncogenic fusion transcripts by oligo microarray analysis. Skotheim RI, et al. Mol Cancer. 2009 Jan 19;8:5.  [PubMed 21009]
  • [V] ETV6 fusion genes in hematological malignancies: A review. De Braekeleer E. et al. Leuk Res. 2012 May 12.   [PubMed 2012]
  • [GT] Cell Lines (Genentech)  [Pubmed 2015]   Nature Biotech Suppl.Table8
  • [FC] Fusion cancer (Beijing) [PubMed 2015] (the fusions are limited to class A and B)
  • [NOR] [PubMed 2016] Babiceanu M et al. Recurrent chimeric fusion RNAs in non-cancer tissues and cells. Nucleic Acids Res. 2016 Feb 2 (Table S3)
  • [URK][PubMed 2016] Urakami et al. Next generation sequencing approach for detecting 491 fusion genes from human cancer. Biomed Res. 2016;37(1):51-62.
  • [AM] [PubMed 2016] Global analysis of somatic structural genomic alterations and their impact on gene expression in diverse human cancersAlaei-Mahabadi B. et al.,Proc Natl Acad Sci U S A. 2016 Nov 16. pii: 201606220.
  • [FM] [PubMed 2018] Genomic hotspots but few recurrent fusion genes in breast cancer, Fimereli et al., Genes Chromosomes Cancer. (SupplTableS2.xls) 2018 Feb 13
  • [MA] [PubMed 2018] Pan-cancer genome and transcriptome analyses of1,699 paediatric leukaemias and solid tumours, Ma et al, Nature (March 2018) Table S3
  • [GAO] [PubMed 2018] Driver Fusions and Their Implications in the Development and Treatment of Human Cancers. Gao et al, Cell Reports (April 2018) Table S2
  • [MAY] [PubMed 2018] Development and Verification of an RNA Sequencing (RNA-Seq) Assay for the Detection of Gene Fusions in Tumor, Winters et al (July 2018) Table S7
  • FusionGDB: fusion gene annotation DataBase. Kim P t Zhou X. Nucleic Acids Res. 2019 Jan 8;47(D1):D994-D1004.[PubMed]site FusionGDB

    Contributor(s)

    Writtenmay 2012Philippe Dessen
      
    Updatedjanv. 2019Philippe Dessen and Jean-Loup Huret

    Citation

    This paper should be referenced as such :
    Dessen P and Huret JL. Chromosomal band 1q11. Atlas Genet Cytogenet Oncol Haematol. July 2012.
    URL : https://atlasgeneticsoncology.usal.es/classic/Bands/1q11.html
    © Atlas of Genetics and Cytogenetics in Oncology and Haematology
    indexed on : mar. janv. 22 11:41:33 CET 2019

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