Chromosome 22

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ENTITIES: by Chromosome band

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Chromosome 22

[previous]   22 22p 22q 22p13 22p12 22p11 22q11 22q12 22q13   [next]

Band 22p11

chr22:9400000-15000000 (5600 Kb)

  • Chromosomal abnormalities in band 22p11
  • Genes in band 22p11 (reference hg38)
  • External links
  • References

    Chromosomal abnormalities in band 22p11

    (click on headers to reorder columns)
    Band 1Band 2ClassEntityPartner 1Partner 2LinksTopographyMorphology[PubMed][Study]
    22p1122q13Cosmic_SVdel(22)(p11q13)  Cosmic_SV [COST196447]prostate__NScarcinoma__adenocarcinoma[PubMed] 
    22p1122q13Cosmic_SVdel(22)(p11q13)  Cosmic_SV [COST196457]prostate__NScarcinoma__adenocarcinoma[PubMed] 
    1q1022p11Mitelmander(22)t(1;22)(q10;p11)  Mitelman (CGAP) Multiple myeloma  
    1q1122p11Mitelmander(22)t(1;22)(q11;p11)  Mitelman (CGAP) Acute lymphoblastic leukemia/lymphoblastic lymphoma  
    1q1222p11Mitelmander(22)t(1;22)(q12;p11)  Mitelman (CGAP) Follicular lymphoma  
    1q1222p11Mitelmander(22)t(1;22)(q12;p11)  Mitelman (CGAP) Multiple myeloma  
    1q2122p11Mitelmander(22)t(1;22)(q21;p11)  Mitelman (CGAP) Diffuse large B-cell lymphoma  
    1q2322p11Mitelmander(22)t(1;22)(q23;p11)  Mitelman (CGAP) Acute lymphoblastic leukemia/lymphoblastic lymphoma  
    14q1122p11Mitelmander(22)t(14;22)(q11;p11)  Mitelman (CGAP)BreastAdenocarcinoma  
    7q1122p11Mitelmander(22)t(7;22)(q11;p11)  Mitelman (CGAP) Acute erythroleukemia (FAB type M6)  
    8q1122p11Mitelmander(22)t(8;22)(q11;p11)  Mitelman (CGAP)PancreasAdenocarcinoma  
    13p1122p11Mitelmandic(13;22)(p11;p11)  Mitelman (CGAP)BrainMeningioma  
    16q1122p11Mitelmandic(16;22)(q11;p11)  Mitelman (CGAP) Acute myelomonocytic leukemia (FAB type M4)  
    20p1222p11Mitelmandic(20;22)(p12;p11)  Mitelman (CGAP) T-prolymphocytic leukemia  
    21p1122p11Mitelmandic(21;22)(p11;p11)  Mitelman (CGAP) Acute myeloid leukemia, NOS  
    9p1122p11Mitelmandic(9;22)(p11;p11)  Mitelman (CGAP) Acute lymphoblastic leukemia/lymphoblastic lymphoma  
    22p11 Mitelmanidic(22)(p11)  Mitelman (CGAP) Acute erythroleukemia (FAB type M6)  
    22p11 Mitelmanidic(22)(p11)  Mitelman (CGAP) Acute myeloblastic leukemia with maturation (FAB type M2)  
    22p11 Mitelmanidic(22)(p11)  Mitelman (CGAP) Acute myeloid leukemia, NOS  
    22p11 Mitelmanidic(22)(p11)  Mitelman (CGAP) Acute myelomonocytic leukemia (FAB type M4)  
    22p1122q13Cosmic_SVinv(22)(p11q13)  Cosmic_SV [COST199219]prostate__NScarcinoma__adenocarcinoma[PubMed] 
    1q1022p11Mitelmant(1;22)(q10;p11)  Mitelman (CGAP) Multiple myeloma  
    1q1122p11Mitelmant(1;22)(q11;p11)  Mitelman (CGAP) Acute lymphoblastic leukemia/lymphoblastic lymphoma  
    1q1222p11Mitelmant(1;22)(q12;p11)  Mitelman (CGAP) Follicular lymphoma  
    1q1222p11Mitelmant(1;22)(q12;p11)  Mitelman (CGAP) Multiple myeloma  
    1q2122p11Mitelmant(1;22)(q21;p11)  Mitelman (CGAP) Diffuse large B-cell lymphoma  
    1q2322p11Mitelmant(1;22)(q23;p11)  Mitelman (CGAP) Acute lymphoblastic leukemia/lymphoblastic lymphoma  
    13q1122p11Mitelmant(13;22)(q11;p11)  Mitelman (CGAP)BreastAdenocarcinoma  
    14q1122p11Mitelmant(14;22)(q11;p11)  Mitelman (CGAP)BreastAdenocarcinoma  
    18q1122p11dbCRIDt(18;22)(q11;p11.2)  10466Epithelioid Sarcoma[PubMed] 
    3p1322p11dbCRIDt(3;22)(p13;p11)  10206Acute Myelocytic Leukemia[PubMed] 
    3q1122p11dbCRIDt(3;22)(q11;p11)  10114Pancreatic Tumours[PubMed] 
    7q1122p11Mitelmant(7;22)(q11;p11)  Mitelman (CGAP) Acute erythroleukemia (FAB type M6)  
    8q1122p11dbCRIDt(8;22)(q11;p11)  10111Cancer[PubMed] 
    8q1122p11Mitelmant(8;22)(q11;p11)  Mitelman (CGAP)PancreasAdenocarcinoma  
    8q2422p11dbCRIDt(8;22)(q24;p11.1)  10978Burkitt Lymphoma[PubMed] 
    Xp1122p11dbCRIDt(X;22)(p11.3;p11)  11522[PubMed] 
    Xp2222p11dbCRIDt(X;22)(p22.1;p11.1)  10876[PubMed] 

    Genes in band 22p11

    (click on headers to reorder columns)
    GoldenPath hg38Band 1Band 2ClassCloneFusionPartner 1Partner 2LinksTopographyMorphologyPubmedOmimAccession
    chr22:10940597-10961529 - 22p11   Gene [G]     FRG1FP       [Omim] [Entrez]
    chr22:11897406-11956534 + 22p11   Gene [G]     LOC102723769       [Omim] [Entrez]

    [ Bold normal : A; Italic normal :G; Italic small : E ]

    X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 [previous]   22 22p 22q 22p13 22p12 22p11 22q11 22q12 22q13   [next]

    External links

    Mitelman Database [NCI] : Breakpoint 22p11

    [ UCSC ][ enSembl ][ MapView - NCBI ][ 1000Genomes ][ EVS ][ CGWB ][ DGV ][ DBVar ][ OMIM ][ HapMap ][ DECIPHER ] [ ECARUCA ]
    Gene Expression (MSigDB) in 22p11  [ HTC ]  [ NCI ]  [ INV ]

    Global tables

  • Anomalies list (tabulated txt file)
  • Gene list (tabulated txt file)
  • list of gene fusions for each gene (with origins of the data)
  • list of gene fusions by origin (with topography and morphology)
  • References

  • [L] Fusion gene microarray reveals cancer type-specificity among fusion genes. Lovf M et al.Genes Chromosomes Cancer. 2011 May;50(5):348-57.   [PubMed 2011]
  • [S] A universal assay for detection of oncogenic fusion transcripts by oligo microarray analysis. Skotheim RI, et al. Mol Cancer. 2009 Jan 19;8:5.  [PubMed 21009]
  • [V] ETV6 fusion genes in hematological malignancies: A review. De Braekeleer E. et al. Leuk Res. 2012 May 12.   [PubMed 2012]
  • [GT] Cell Lines (Genentech)  [Pubmed 2015]   Nature Biotech Suppl.Table8
  • [FC] Fusion cancer (Beijing) [PubMed 2015] (the fusions are limited to class A and B)
  • [NOR] [PubMed 2016] Babiceanu M et al. Recurrent chimeric fusion RNAs in non-cancer tissues and cells. Nucleic Acids Res. 2016 Feb 2 (Table S3)
  • [URK][PubMed 2016] Urakami et al. Next generation sequencing approach for detecting 491 fusion genes from human cancer. Biomed Res. 2016;37(1):51-62.
  • [AM] [PubMed 2016] Global analysis of somatic structural genomic alterations and their impact on gene expression in diverse human cancersAlaei-Mahabadi B. et al.,Proc Natl Acad Sci U S A. 2016 Nov 16. pii: 201606220.
  • [FM] [PubMed 2018] Genomic hotspots but few recurrent fusion genes in breast cancer, Fimereli et al., Genes Chromosomes Cancer. (SupplTableS2.xls) 2018 Feb 13
  • [MA] [PubMed 2018] Pan-cancer genome and transcriptome analyses of1,699 paediatric leukaemias and solid tumours, Ma et al, Nature (March 2018) Table S3
  • [GAO] [PubMed 2018] Driver Fusions and Their Implications in the Development and Treatment of Human Cancers. Gao et al, Cell Reports (April 2018) Table S2
  • [MAY] [PubMed 2018] Development and Verification of an RNA Sequencing (RNA-Seq) Assay for the Detection of Gene Fusions in Tumor, Winters et al (July 2018) Table S7
  • FusionGDB: fusion gene annotation DataBase. Kim P t Zhou X. Nucleic Acids Res. 2019 Jan 8;47(D1):D994-D1004.[PubMed]site FusionGDB


    Writtenmay 2012Philippe Dessen
    Updatedjanv. 2019Philippe Dessen and Jean-Loup Huret


    This paper should be referenced as such :
    Dessen P and Huret JL. Chromosomal band 22p11. Atlas Genet Cytogenet Oncol Haematol. July 2012.
    URL :
    © Atlas of Genetics and Cytogenetics in Oncology and Haematology
    indexed on : mar. janv. 22 11:56:28 CET 2019

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