Chromosome Y

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Chromosome Y

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Band Yq12

chrY:26600000-57227415 (30627.415 Kb)

  • Chromosomal abnormalities in band Yq12
  • Genes in band Yq12 (reference hg38)
  • External links
  • References

    Chromosomal abnormalities in band Yq12

    (click on headers to reorder columns)
    Band 1Band 2ClassEntityPartner 1Partner 2LinksTopographyMorphology[PubMed][Study]
    Yq12 Mitelmandel(Y)(q12)  Mitelman (CGAP) Acute lymphoblastic leukemia/lymphoblastic lymphoma  
    Yq12 Mitelmandel(Y)(q12)  Mitelman (CGAP) Acute myelomonocytic leukemia (FAB type M4)  
    Yq12 Mitelmandel(Y)(q12)  Mitelman (CGAP)KidneyAdenocarcinoma  
    Yq121q21Mitelmander(Y)t(Y;1)(q12;q21)  Mitelman (CGAP) Acute myeloblastic leukemia with maturation (FAB type M2)  
    Yq121q21Mitelmander(Y)t(Y;1)(q12;q21)  Mitelman (CGAP) Refractory anemia with excess blasts-2  
    Yq121q25dbCRIDder(Y)t(Y;1)(q12;q25)  11292Kabuki Syndrome,acute Myeloid Leukemia[PubMed] 
    Yq122p11Mitelmander(Y)t(Y;2)(q12;p11)  Mitelman (CGAP) Multiple myeloma  
    Yq123q21Mitelmander(Y)t(Y;3)(q12;q21)  Mitelman (CGAP) Acute myeloid leukemia, NOS  
    Yp11Yq12dbCRIDinv(Y)(p11.31q12)  10641Gonadoblastoma[PubMed] 
    Yq1214p11dbCRIDt(Y;14)(q12;p11)  10378Infertility[PubMed] 
    Yq1214q24dbCRIDt(Y;14)(q12;q24)  11622Dupuytren Contracture[PubMed] 
    Yq1216q24dbCRIDt(Y;16)(q12;q24.3)  10361Lymphedema-distichiasis[PubMed] 
    Yq121q12dbCRIDt(Y;1)(q12;q12)  10548Polycythemia Vera[PubMed] 
    Yq121q21Mitelmant(Y;1)(q12;q21)  Mitelman (CGAP) Acute myeloblastic leukemia with maturation (FAB type M2)  
    Yq121q21Mitelmant(Y;1)(q12;q21)  Mitelman (CGAP) Refractory anemia with excess blasts-2  
    Yq122p11Mitelmant(Y;2)(q12;p11)  Mitelman (CGAP) Multiple myeloma  
    Yq123q21Mitelmant(Y;3)(q12;q21)  Mitelman (CGAP) Acute myeloid leukemia, NOS  
    Yq126p11dbCRIDt(Y;6)(q12;p11.1)  11496Infertility[PubMed] 

    Genes in band Yq12

    (click on headers to reorder columns)
    GoldenPath hg38Band 1Band 2ClassCloneFusionPartner 1Partner 2LinksTopographyMorphologyPubmedOmimAccession

    [ Bold normal : A; Italic normal :G; Italic small : E ]

    X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 [previous]   Y Yp Yq Yp11 Yq11 Yq12   [next]

    External links

    Mitelman Database [NCI] : Breakpoint Yq12

    [ UCSC ][ enSembl ][ MapView - NCBI ][ 1000Genomes ][ EVS ][ CGWB ][ DGV ][ DBVar ][ OMIM ][ HapMap ][ DECIPHER ] [ ECARUCA ]
    Gene Expression (MSigDB) in Yq12  [ HTC ]  [ NCI ]  [ INV ]

    Global tables

  • Anomalies list (tabulated txt file)
  • Gene list (tabulated txt file)
  • list of gene fusions for each gene (with origins of the data)
  • list of gene fusions by origin (with topography and morphology)
  • References

  • [L] Fusion gene microarray reveals cancer type-specificity among fusion genes. Lovf M et al.Genes Chromosomes Cancer. 2011 May;50(5):348-57.   [PubMed 2011]
  • [S] A universal assay for detection of oncogenic fusion transcripts by oligo microarray analysis. Skotheim RI, et al. Mol Cancer. 2009 Jan 19;8:5.  [PubMed 21009]
  • [V] ETV6 fusion genes in hematological malignancies: A review. De Braekeleer E. et al. Leuk Res. 2012 May 12.   [PubMed 2012]
  • [GT] Cell Lines (Genentech)  [Pubmed 2015]   Nature Biotech Suppl.Table8
  • [FC] Fusion cancer (Beijing) [PubMed 2015] (the fusions are limited to class A and B)
  • [NOR] [PubMed 2016] Babiceanu M et al. Recurrent chimeric fusion RNAs in non-cancer tissues and cells. Nucleic Acids Res. 2016 Feb 2 (Table S3)
  • [URK][PubMed 2016] Urakami et al. Next generation sequencing approach for detecting 491 fusion genes from human cancer. Biomed Res. 2016;37(1):51-62.
  • [AM] [PubMed 2016] Global analysis of somatic structural genomic alterations and their impact on gene expression in diverse human cancersAlaei-Mahabadi B. et al.,Proc Natl Acad Sci U S A. 2016 Nov 16. pii: 201606220.
  • [FM] [PubMed 2018] Genomic hotspots but few recurrent fusion genes in breast cancer, Fimereli et al., Genes Chromosomes Cancer. (SupplTableS2.xls) 2018 Feb 13
  • [MA] [PubMed 2018] Pan-cancer genome and transcriptome analyses of1,699 paediatric leukaemias and solid tumours, Ma et al, Nature (March 2018) Table S3
  • [GAO] [PubMed 2018] Driver Fusions and Their Implications in the Development and Treatment of Human Cancers. Gao et al, Cell Reports (April 2018) Table S2
  • [MAY] [PubMed 2018] Development and Verification of an RNA Sequencing (RNA-Seq) Assay for the Detection of Gene Fusions in Tumor, Winters et al (July 2018) Table S7
  • FusionGDB: fusion gene annotation DataBase. Kim P t Zhou X. Nucleic Acids Res. 2019 Jan 8;47(D1):D994-D1004.[PubMed]site FusionGDB


    Writtenmay 2012Philippe Dessen
    Updatedjanv. 2019Philippe Dessen and Jean-Loup Huret


    This paper should be referenced as such :
    Dessen P and Huret JL. Chromosomal band Yq12. Atlas Genet Cytogenet Oncol Haematol. July 2012.
    URL :
    © Atlas of Genetics and Cytogenetics in Oncology and Haematology
    indexed on : mar. janv. 22 11:57:34 CET 2019

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