ABCF1 (ATP binding cassette subfamily F member 1)

1. Identity

Alias_names
General Information
ATP-binding cassette
Alias_symbol (synonym)EST123147
Other aliasABC27
HGNC (Hugo) ABCF1
LocusID (NCBI) 23
Atlas_Id 544
Location 6p21.33  [Link to chromosome band 6p21]
Location_base_pair Starts at 30571393 and ends at 30591532 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ABCF1 (6p21.33) / ABCF1 (6p21.33)ABCF1 (6p21.33) / LOC283624 ()MTHFS (15q25.1) / ABCF1 (6p21.33)
PLVAP (19p13.11) / ABCF1 (6p21.33)RPL18 (19q13.33) / ABCF1 (6p21.33)S100A6 (1q21.3) / ABCF1 (6p21.33)
TUBB (6p21.33) / ABCF1 (6p21.33)PLVAP 19p13.11 / ABCF1 6p21.33RPL18 19q13.33 / ABCF1 6p21.33
S100A6 1q21.3 / ABCF1 6p21.33

2. DNA/RNA

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 3 ]
  t(1;6)(q21;p21) S100A6/ABCF1
t(6;19)(p21;p13) PLVAP/ABCF1
t(6;19)(p21;q13) RPL18/ABCF1

3. External links

Nomenclature
HGNC (Hugo)ABCF1   70
Cards
Entrez_Gene (NCBI)ABCF1  23  ATP binding cassette subfamily F member 1
AliasesABC27; ABC50
GeneCards (Weizmann)ABCF1
Ensembl hg19 (Hinxton)ENSG00000204574 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000204574 [Gene_View] &nbspENSG00000204574 [Sequence]  chr6:30571393-30591532 [Contig_View]  ABCF1 [Vega]
ICGC DataPortalENSG00000204574
TCGA cBioPortalABCF1
AceView (NCBI)ABCF1
Genatlas (Paris)ABCF1
WikiGenes23
SOURCE (Princeton)ABCF1
Genetics Home Reference (NIH)ABCF1
Genomic and cartography
GoldenPath hg38 (UCSC)ABCF1  -     chr6:30571393-30591532 +  6p21.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ABCF1  -     6p21.33   [Description]    (hg19-Feb_2009)
EnsemblABCF1 - 6p21.33 [CytoView hg19]  ABCF1 - 6p21.33 [CytoView hg38]
Mapping of homologs : NCBIABCF1 [Mapview hg19]  ABCF1 [Mapview hg38]
OMIM603429   
Gene and transcription
Genbank (Entrez)AB209564 AF027302 AK298061 AK307551 AL832430
RefSeq transcript (Entrez)NM_001025091 NM_001090
RefSeq genomic (Entrez)NC_000006 NG_047030 NT_113891 NT_167245 NT_167246 NT_167247 NT_167248 NT_167249
Consensus coding sequences : CCDS (NCBI)ABCF1
Cluster EST : UnigeneHs.655285 [ NCBI ]
CGAP (NCI)Hs.655285
Alternative Splicing GalleryENSG00000204574
Gene ExpressionABCF1 [ NCBI-GEO ]   ABCF1 [ EBI - ARRAY_EXPRESS ]   ABCF1 [ SEEK ]   ABCF1 [ MEM ]
Gene Expression Viewer (FireBrowse)ABCF1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets] &nbsp [Normal Tissue Atlas] &nbsp[carcinoma Classsification] &nbsp[NCI60]
GenevestigatorExpression in : [tissues] &nbsp[cell-lines] &nbsp[cancer] &nbsp[perturbations] &nbsp
BioGPS (Tissue expression)23
GTEX Portal (Tissue expression)ABCF1
Human Protein AtlasENSG00000204574-ABCF1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NE71   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NE71  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NE71
Splice isoforms : SwissVarQ8NE71
PhosPhoSitePlusQ8NE71
Domaine pattern : Prosite (Expaxy)ABC_TRANSPORTER_1 (PS00211)    ABC_TRANSPORTER_2 (PS50893)   
Domains : Interpro (EBI)AAA+_ATPase    ABC_tran_Xtn    ABC_transporter-like    ABC_transporter_CS    P-loop_NTPase   
Domain families : Pfam (Sanger)ABC_tran (PF00005)    ABC_tran_Xtn (PF12848)   
Domain families : Pfam (NCBI)pfam00005    pfam12848   
Domain families : Smart (EMBL)AAA (SM00382)  
Conserved Domain (NCBI)ABCF1
DMDM Disease mutations23
Blocks (Seattle)ABCF1
SuperfamilyQ8NE71
Human Protein Atlas [tissue]ENSG00000204574-ABCF1 [tissue]
Peptide AtlasQ8NE71
HPRD09139
IPIIPI00873899   IPI00013495   IPI01013194   IPI00792186   IPI00642673   IPI01015998   
Protein Interaction databases
DIP (DOE-UCLA)Q8NE71
IntAct (EBI)Q8NE71
FunCoupENSG00000204574
BioGRIDABCF1
STRING (EMBL)ABCF1
ZODIACABCF1
Ontologies - Pathways
QuickGOQ8NE71
Ontology : AmiGORNA binding  protein binding  ATP binding  nuclear envelope  nucleoplasm  cytosol  cytosol  ribosome  translation  inflammatory response  translation factor activity, RNA binding  membrane  ATPase activity  transmembrane transport  
Ontology : EGO-EBIRNA binding  protein binding  ATP binding  nuclear envelope  nucleoplasm  cytosol  cytosol  ribosome  translation  inflammatory response  translation factor activity, RNA binding  membrane  ATPase activity  transmembrane transport  
NDEx NetworkABCF1
Atlas of Cancer Signalling NetworkABCF1
Wikipedia pathwaysABCF1
Orthology - Evolution
OrthoDB23
GeneTree (enSembl)ENSG00000204574
Phylogenetic Trees/Animal Genes : TreeFamABCF1
HOGENOMQ8NE71
Homologs : HomoloGeneABCF1
Homology/Alignments : Family Browser (UCSC)ABCF1
Gene fusions - Rearrangements
Fusion : MitelmanPLVAP/ABCF1 [19p13.11/6p21.33] &nbsp[t(6;19)(p21;p13)]  
Fusion : MitelmanRPL18/ABCF1 [19q13.33/6p21.33] &nbsp[t(6;19)(p21;q13)]  
Fusion : MitelmanS100A6/ABCF1 [1q21.3/6p21.33] &nbsp[t(1;6)(q21;p21)]  
Fusion PortalPLVAP 19p13.11 ABCF1 6p21.33 THCA
Fusion PortalRPL18 19q13.33 ABCF1 6p21.33 HNSC
Fusion PortalS100A6 1q21.3 ABCF1 6p21.33 LUAD
Fusion : QuiverABCF1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerABCF1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ABCF1
dbVarABCF1
ClinVarABCF1
1000_GenomesABCF1 
Exome Variant ServerABCF1
ExAC (Exome Aggregation Consortium)ENSG00000204574
GNOMAD BrowserENSG00000204574
Varsome BrowserABCF1
Genetic variants : HAPMAP23
Genomic Variants (DGV)ABCF1 [DGVbeta]
DECIPHERABCF1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisABCF1 
Mutations
ICGC Data PortalABCF1 
TCGA Data PortalABCF1 
Broad Tumor PortalABCF1
OASIS PortalABCF1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICABCF1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDABCF1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ABCF1
DgiDB (Drug Gene Interaction Database)ABCF1
DoCM (Curated mutations)ABCF1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ABCF1 (select a term)
intoGenABCF1
Cancer3DABCF1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603429   
Orphanet
DisGeNETABCF1
MedgenABCF1
Genetic Testing Registry ABCF1
NextProtQ8NE71 [Medical]
TSGene23
GENETestsABCF1
Target ValidationABCF1
Huge Navigator ABCF1 [HugePedia]
snp3D : Map Gene to Disease23
BioCentury BCIQABCF1
ClinGenABCF1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23
Chemical/Pharm GKB GenePA24405
Clinical trialABCF1
Miscellaneous
canSAR (ICR)ABCF1 (select the gene name)
DataMed IndexABCF1
Probes
Litterature
PubMed61 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineABCF1
EVEXABCF1
GoPubMedABCF1
iHOPABCF1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Jan 17 17:59:32 CET 2019

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