ASB9 (ankyrin repeat and SOCS box containing 9)

1. Identity

Alias_names
General Information
Alias_symbol (synonym)DKFZP564L0862
MGC4954
FLJ20636
Other alias-
HGNC (Hugo) ASB9
LocusID (NCBI) 140462
Atlas_Id 52072
Location Xp22.2  [Link to chromosome band Xp22]
Location_base_pair Starts at 15243987 and ends at 15270171 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
TRIM41 (5q35.3) / ASB9 (Xp22.2)WDR59 (16q23.1) / ASB9 (Xp22.2)TRIM41 5q35.3 / ASB9 Xp22.2
WDR59 16q23.1 / ASB9 Xp22.2

2. DNA/RNA

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]
  t(X;5)(p22;q35) TRIM41/ASB9
t(X;16)(p22;q23) WDR59/ASB9

3. External links

Nomenclature
HGNC (Hugo)ASB9   17184
Cards
Entrez_Gene (NCBI)ASB9  140462  ankyrin repeat and SOCS box containing 9
Aliases
GeneCards (Weizmann)ASB9
Ensembl hg19 (Hinxton)ENSG00000102048 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000102048 [Gene_View] &nbspENSG00000102048 [Sequence]  chrX:15243987-15270171 [Contig_View]  ASB9 [Vega]
ICGC DataPortalENSG00000102048
TCGA cBioPortalASB9
AceView (NCBI)ASB9
Genatlas (Paris)ASB9
WikiGenes140462
SOURCE (Princeton)ASB9
Genetics Home Reference (NIH)ASB9
Genomic and cartography
GoldenPath hg38 (UCSC)ASB9  -     chrX:15243987-15270171 -  Xp22.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ASB9  -     Xp22.2   [Description]    (hg19-Feb_2009)
EnsemblASB9 - Xp22.2 [CytoView hg19]  ASB9 - Xp22.2 [CytoView hg38]
Mapping of homologs : NCBIASB9 [Mapview hg19]  ASB9 [Mapview hg38]
OMIM300890   
Gene and transcription
Genbank (Entrez)AK000643 AK292270 AL080091 AY337578 BC001244
RefSeq transcript (Entrez)NM_001031739 NM_001168530 NM_001168531 NM_024087
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ASB9
Cluster EST : UnigeneHs.19404 [ NCBI ]
CGAP (NCI)Hs.19404
Alternative Splicing GalleryENSG00000102048
Gene ExpressionASB9 [ NCBI-GEO ]   ASB9 [ EBI - ARRAY_EXPRESS ]   ASB9 [ SEEK ]   ASB9 [ MEM ]
Gene Expression Viewer (FireBrowse)ASB9 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets] &nbsp [Normal Tissue Atlas] &nbsp[carcinoma Classsification] &nbsp[NCI60]
GenevestigatorExpression in : [tissues] &nbsp[cell-lines] &nbsp[cancer] &nbsp[perturbations] &nbsp
BioGPS (Tissue expression)140462
GTEX Portal (Tissue expression)ASB9
Human Protein AtlasENSG00000102048-ASB9 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96DX5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96DX5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96DX5
Splice isoforms : SwissVarQ96DX5
PhosPhoSitePlusQ96DX5
Domaine pattern : Prosite (Expaxy)ANK_REP_REGION (PS50297)    ANK_REPEAT (PS50088)    SOCS (PS50225)   
Domains : Interpro (EBI)Ankyrin_rpt    Ankyrin_rpt-contain_dom    Ankyrin_rpt-contain_sf    ASB9/11_SOCS    SOCS_box    SOCS_box-like_dom_sf   
Domain families : Pfam (Sanger)Ank_2 (PF12796)    SOCS_box (PF07525)   
Domain families : Pfam (NCBI)pfam12796    pfam07525   
Domain families : Smart (EMBL)ANK (SM00248)  SOCS_box (SM00969)  
Conserved Domain (NCBI)ASB9
DMDM Disease mutations140462
Blocks (Seattle)ASB9
PDB (RSDB)3D9H    3ZKJ    3ZNG   
PDB Europe3D9H    3ZKJ    3ZNG   
PDB (PDBSum)3D9H    3ZKJ    3ZNG   
PDB (IMB)3D9H    3ZKJ    3ZNG   
Structural Biology KnowledgeBase3D9H    3ZKJ    3ZNG   
SCOP (Structural Classification of Proteins)3D9H    3ZKJ    3ZNG   
CATH (Classification of proteins structures)3D9H    3ZKJ    3ZNG   
SuperfamilyQ96DX5
Human Protein Atlas [tissue]ENSG00000102048-ASB9 [tissue]
Peptide AtlasQ96DX5
HPRD06452
IPIIPI00179183   IPI00216580   IPI00385067   IPI00643086   
Protein Interaction databases
DIP (DOE-UCLA)Q96DX5
IntAct (EBI)Q96DX5
FunCoupENSG00000102048
BioGRIDASB9
STRING (EMBL)ASB9
ZODIACASB9
Ontologies - Pathways
QuickGOQ96DX5
Ontology : AmiGOprotein binding  mitochondrion  cytosol  protein ubiquitination  protein ubiquitination  protein ubiquitination  intracellular signal transduction  post-translational protein modification  positive regulation of protein catabolic process  positive regulation of protein catabolic process  
Ontology : EGO-EBIprotein binding  mitochondrion  cytosol  protein ubiquitination  protein ubiquitination  protein ubiquitination  intracellular signal transduction  post-translational protein modification  positive regulation of protein catabolic process  positive regulation of protein catabolic process  
NDEx NetworkASB9
Atlas of Cancer Signalling NetworkASB9
Wikipedia pathwaysASB9
Orthology - Evolution
OrthoDB140462
GeneTree (enSembl)ENSG00000102048
Phylogenetic Trees/Animal Genes : TreeFamASB9
HOGENOMQ96DX5
Homologs : HomoloGeneASB9
Homology/Alignments : Family Browser (UCSC)ASB9
Gene fusions - Rearrangements
Fusion : MitelmanTRIM41/ASB9 [5q35.3/Xp22.2] &nbsp[t(X;5)(p22;q35)]  
Fusion : MitelmanWDR59/ASB9 [16q23.1/Xp22.2] &nbsp[t(X;16)(p22;q23)]  
Fusion PortalTRIM41 5q35.3 ASB9 Xp22.2 LUAD
Fusion PortalWDR59 16q23.1 ASB9 Xp22.2 GBM
Fusion : QuiverASB9
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerASB9 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ASB9
dbVarASB9
ClinVarASB9
1000_GenomesASB9 
Exome Variant ServerASB9
ExAC (Exome Aggregation Consortium)ENSG00000102048
GNOMAD BrowserENSG00000102048
Varsome BrowserASB9
Genetic variants : HAPMAP140462
Genomic Variants (DGV)ASB9 [DGVbeta]
DECIPHERASB9 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisASB9 
Mutations
ICGC Data PortalASB9 
TCGA Data PortalASB9 
Broad Tumor PortalASB9
OASIS PortalASB9 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICASB9  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDASB9
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
BioMutasearch ASB9
DgiDB (Drug Gene Interaction Database)ASB9
DoCM (Curated mutations)ASB9 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ASB9 (select a term)
intoGenASB9
Cancer3DASB9(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300890   
Orphanet
DisGeNETASB9
MedgenASB9
Genetic Testing Registry ASB9
NextProtQ96DX5 [Medical]
TSGene140462
GENETestsASB9
Target ValidationASB9
Huge Navigator ASB9 [HugePedia]
snp3D : Map Gene to Disease140462
BioCentury BCIQASB9
ClinGenASB9
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD140462
Chemical/Pharm GKB GenePA25037
Clinical trialASB9
Miscellaneous
canSAR (ICR)ASB9 (select the gene name)
DataMed IndexASB9
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineASB9
EVEXASB9
GoPubMedASB9
iHOPASB9
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Jan 17 18:02:05 CET 2019

For comments and suggestions or contributions, please contact us atlasgeneticsoncology@usal.es.