BSG (basigin (Ok blood group))

1. Identity

Alias_names
General Information
basigin
Alias_symbol (synonym)EMMPRIN
CD147
Other alias5F7
EMPRIN
SLC7A11
TCSF
HGNC (Hugo) BSG
LocusID (NCBI) 682
Atlas_Id 845
Location 19p13.3  [Link to chromosome band 19p13]
Location_base_pair Starts at 571277 and ends at 583493 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ACTB (7p22.1) / BSG (19p13.3)BSG (19p13.3) / ARFGEF2 (20q13.13)BSG (19p13.3) / BSG (19p13.3)
BSG (19p13.3) / EEA1 (12q22)BSG (19p13.3) / FBXL19 (16p11.2)BSG (19p13.3) / GZMM (19p13.3)
BSG (19p13.3) / NFIX (19p13.2)BSG (19p13.3) / SLC1A3 (5p13.2)BSG (19p13.3) / TMEM8A (16p13.3)
BSG (19p13.3) / ZKSCAN1 (7q22.1)HCN2 (19p13.3) / BSG (19p13.3)BSG 19p13.3 / ARFGEF2 20q13.13
BSG 19p13.3 / EEA1 12q22HCN2 19p13.3 / BSG 19p13.3

2. DNA/RNA

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 4 ]
  t(12;19)(q22;p13) BSG/EEA1
BSG/NFIX (19p13)
HCN2/BSG (19p13)
t(19;20)(p13;q13) BSG/ARFGEF2

3. External links

Nomenclature
HGNC (Hugo)BSG   1116
LRG (Locus Reference Genomic)LRG_816
Cards
Entrez_Gene (NCBI)BSG  682  basigin (Ok blood group)
Aliases5F7; CD147; EMMPRIN; EMPRIN; 
OK; SLC7A11; TCSF
GeneCards (Weizmann)BSG
Ensembl hg19 (Hinxton)ENSG00000172270 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000172270 [Gene_View] &nbspENSG00000172270 [Sequence]  chr19:571277-583493 [Contig_View]  BSG [Vega]
ICGC DataPortalENSG00000172270
TCGA cBioPortalBSG
AceView (NCBI)BSG
Genatlas (Paris)BSG
WikiGenes682
SOURCE (Princeton)BSG
Genetics Home Reference (NIH)BSG
Genomic and cartography
GoldenPath hg38 (UCSC)BSG  -     chr19:571277-583493 +  19p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)BSG  -     19p13.3   [Description]    (hg19-Feb_2009)
EnsemblBSG - 19p13.3 [CytoView hg19]  BSG - 19p13.3 [CytoView hg38]
Mapping of homologs : NCBIBSG [Mapview hg19]  BSG [Mapview hg38]
OMIM109480   111380   
Gene and transcription
Genbank (Entrez)AB072923 AB085790 AB091680 AF548371 AK095912
RefSeq transcript (Entrez)NM_001322243 NM_001728 NM_198589 NM_198590 NM_198591
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)BSG
Cluster EST : UnigeneHs.501293 [ NCBI ]
CGAP (NCI)Hs.501293
Alternative Splicing GalleryENSG00000172270
Gene ExpressionBSG [ NCBI-GEO ]   BSG [ EBI - ARRAY_EXPRESS ]   BSG [ SEEK ]   BSG [ MEM ]
Gene Expression Viewer (FireBrowse)BSG [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets] &nbsp [Normal Tissue Atlas] &nbsp[carcinoma Classsification] &nbsp[NCI60]
GenevestigatorExpression in : [tissues] &nbsp[cell-lines] &nbsp[cancer] &nbsp[perturbations] &nbsp
BioGPS (Tissue expression)682
GTEX Portal (Tissue expression)BSG
Human Protein AtlasENSG00000172270-BSG [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP35613   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP35613  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP35613
Splice isoforms : SwissVarP35613
PhosPhoSitePlusP35613
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)   
Domains : Interpro (EBI)Basigin    Ig-like_dom    Ig-like_dom_sf    Ig-like_fold    Ig_sub    Ig_sub2   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)IG (SM00409)  IGc2 (SM00408)  
Conserved Domain (NCBI)BSG
DMDM Disease mutations682
Blocks (Seattle)BSG
PDB (RSDB)3B5H    3I84    3I85    3QQN    3QR2    4U0Q    5X0T   
PDB Europe3B5H    3I84    3I85    3QQN    3QR2    4U0Q    5X0T   
PDB (PDBSum)3B5H    3I84    3I85    3QQN    3QR2    4U0Q    5X0T   
PDB (IMB)3B5H    3I84    3I85    3QQN    3QR2    4U0Q    5X0T   
Structural Biology KnowledgeBase3B5H    3I84    3I85    3QQN    3QR2    4U0Q    5X0T   
SCOP (Structural Classification of Proteins)3B5H    3I84    3I85    3QQN    3QR2    4U0Q    5X0T   
CATH (Classification of proteins structures)3B5H    3I84    3I85    3QQN    3QR2    4U0Q    5X0T   
SuperfamilyP35613
Human Protein Atlas [tissue]ENSG00000172270-BSG [tissue]
Peptide AtlasP35613
HPRD00176
IPIIPI00218019   IPI00019906   IPI00908477   IPI01010766   IPI00394877   
Protein Interaction databases
DIP (DOE-UCLA)P35613
IntAct (EBI)P35613
FunCoupENSG00000172270
BioGRIDBSG
STRING (EMBL)BSG
ZODIACBSG
Ontologies - Pathways
QuickGOP35613
Ontology : AmiGOGolgi membrane  acrosomal membrane  protein binding  mannose binding  mitochondrion  plasma membrane  plasma membrane  plasma membrane  plasma membrane  integral component of plasma membrane  focal adhesion  pyruvate metabolic process  homophilic cell adhesion via plasma membrane adhesion molecules  cell surface receptor signaling pathway  axon guidance  embryo implantation  monocarboxylic acid transmembrane transporter activity  monocarboxylic acid transport  membrane  extracellular matrix disassembly  extracellular matrix organization  axon  sarcolemma  melanosome  odontogenesis of dentin-containing tooth  intracellular membrane-bounded organelle  response to peptide hormone  membrane raft  cadherin binding  response to mercury ion  decidualization  leukocyte migration  response to cAMP  extracellular exosome  dendrite self-avoidance  protein localization to plasma membrane  cell-cell adhesion mediator activity  
Ontology : EGO-EBIGolgi membrane  acrosomal membrane  protein binding  mannose binding  mitochondrion  plasma membrane  plasma membrane  plasma membrane  plasma membrane  integral component of plasma membrane  focal adhesion  pyruvate metabolic process  homophilic cell adhesion via plasma membrane adhesion molecules  cell surface receptor signaling pathway  axon guidance  embryo implantation  monocarboxylic acid transmembrane transporter activity  monocarboxylic acid transport  membrane  extracellular matrix disassembly  extracellular matrix organization  axon  sarcolemma  melanosome  odontogenesis of dentin-containing tooth  intracellular membrane-bounded organelle  response to peptide hormone  membrane raft  cadherin binding  response to mercury ion  decidualization  leukocyte migration  response to cAMP  extracellular exosome  dendrite self-avoidance  protein localization to plasma membrane  cell-cell adhesion mediator activity  
NDEx NetworkBSG
Atlas of Cancer Signalling NetworkBSG
Wikipedia pathwaysBSG
Orthology - Evolution
OrthoDB682
GeneTree (enSembl)ENSG00000172270
Phylogenetic Trees/Animal Genes : TreeFamBSG
HOGENOMP35613
Homologs : HomoloGeneBSG
Homology/Alignments : Family Browser (UCSC)BSG
Gene fusions - Rearrangements
Fusion : MitelmanBSG/ARFGEF2 [19p13.3/20q13.13] &nbsp
Fusion : MitelmanBSG/EEA1 [19p13.3/12q22] &nbsp[t(12;19)(q22;p13)]  
Fusion : MitelmanBSG/NFIX [19p13.3/19p13.2] &nbsp[t(19;19)(p13;p13)]  
Fusion : MitelmanHCN2/BSG [19p13.3/19p13.3] &nbsp[t(19;19)(p13;p13)]  
Fusion PortalBSG 19p13.3 ARFGEF2 20q13.13 LGG
Fusion PortalBSG 19p13.3 EEA1 12q22 THCA
Fusion PortalHCN2 19p13.3 BSG 19p13.3 LGG
Fusion : QuiverBSG
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerBSG [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)BSG
dbVarBSG
ClinVarBSG
1000_GenomesBSG 
Exome Variant ServerBSG
ExAC (Exome Aggregation Consortium)ENSG00000172270
GNOMAD BrowserENSG00000172270
Varsome BrowserBSG
Genetic variants : HAPMAP682
Genomic Variants (DGV)BSG [DGVbeta]
DECIPHERBSG [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisBSG 
Mutations
ICGC Data PortalBSG 
TCGA Data PortalBSG 
Broad Tumor PortalBSG
OASIS PortalBSG [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICBSG  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDBSG
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch BSG
DgiDB (Drug Gene Interaction Database)BSG
DoCM (Curated mutations)BSG (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)BSG (select a term)
intoGenBSG
Cancer3DBSG(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM109480    111380   
Orphanet
DisGeNETBSG
MedgenBSG
Genetic Testing Registry BSG
NextProtP35613 [Medical]
TSGene682
GENETestsBSG
Target ValidationBSG
Huge Navigator BSG [HugePedia]
snp3D : Map Gene to Disease682
BioCentury BCIQBSG
ClinGenBSG
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD682
Chemical/Pharm GKB GenePA25433
Clinical trialBSG
Miscellaneous
canSAR (ICR)BSG (select the gene name)
DataMed IndexBSG
Probes
Litterature
PubMed499 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineBSG
EVEXBSG
GoPubMedBSG
iHOPBSG
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Jan 17 18:03:34 CET 2019

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