CDC25B (cell division cycle 25B)

1. Identity

Alias_names
General Information
cell division cycle 25 homolog B (S. cerevisiae)
cell division cycle 25 homolog B (S. pombe)
Other alias-
HGNC (Hugo) CDC25B
LocusID (NCBI) 994
Atlas_Id 40005
Location 20p13  [Link to chromosome band 20p13]
Location_base_pair Starts at 3795739 and ends at 3806121 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CDC25B (20p13) / CDC25B (20p13)

2. DNA/RNA

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

 

3. External links

Nomenclature
HGNC (Hugo)CDC25B   1726
Cards
Entrez_Gene (NCBI)CDC25B  994  cell division cycle 25B
Aliases
GeneCards (Weizmann)CDC25B
Ensembl hg19 (Hinxton)ENSG00000101224 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000101224 [Gene_View] &nbspENSG00000101224 [Sequence]  chr20:3795739-3806121 [Contig_View]  CDC25B [Vega]
ICGC DataPortalENSG00000101224
TCGA cBioPortalCDC25B
AceView (NCBI)CDC25B
Genatlas (Paris)CDC25B
WikiGenes994
SOURCE (Princeton)CDC25B
Genetics Home Reference (NIH)CDC25B
Genomic and cartography
GoldenPath hg38 (UCSC)CDC25B  -     chr20:3795739-3806121 +  20p13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CDC25B  -     20p13   [Description]    (hg19-Feb_2009)
EnsemblCDC25B - 20p13 [CytoView hg19]  CDC25B - 20p13 [CytoView hg38]
Mapping of homologs : NCBICDC25B [Mapview hg19]  CDC25B [Mapview hg38]
OMIM116949   
Gene and transcription
Genbank (Entrez)AK092713 AK124284 AK295573 AK299028 AK299192
RefSeq transcript (Entrez)NM_001287516 NM_001287517 NM_001287518 NM_001287519 NM_001287520 NM_001287522 NM_001287524 NM_004358 NM_021872 NM_021873 NM_021874 NM_212530
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CDC25B
Cluster EST : UnigeneHs.153752 [ NCBI ]
CGAP (NCI)Hs.153752
Alternative Splicing GalleryENSG00000101224
Gene ExpressionCDC25B [ NCBI-GEO ]   CDC25B [ EBI - ARRAY_EXPRESS ]   CDC25B [ SEEK ]   CDC25B [ MEM ]
Gene Expression Viewer (FireBrowse)CDC25B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets] &nbsp [Normal Tissue Atlas] &nbsp[carcinoma Classsification] &nbsp[NCI60]
GenevestigatorExpression in : [tissues] &nbsp[cell-lines] &nbsp[cancer] &nbsp[perturbations] &nbsp
BioGPS (Tissue expression)994
GTEX Portal (Tissue expression)CDC25B
Human Protein AtlasENSG00000101224-CDC25B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP30305   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP30305  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP30305
Splice isoforms : SwissVarP30305
Catalytic activity : Enzyme3.1.3.48 [ Enzyme-Expasy ]   3.1.3.483.1.3.48 [ IntEnz-EBI ]   3.1.3.48 [ BRENDA ]   3.1.3.48 [ KEGG ]   
PhosPhoSitePlusP30305
Domaine pattern : Prosite (Expaxy)RHODANESE_3 (PS50206)   
Domains : Interpro (EBI)MPI_Phosphatase    Rhodanese-like_dom    Rhodanese-like_dom_sf   
Domain families : Pfam (Sanger)M-inducer_phosp (PF06617)    Rhodanese (PF00581)   
Domain families : Pfam (NCBI)pfam06617    pfam00581   
Domain families : Smart (EMBL)RHOD (SM00450)  
Conserved Domain (NCBI)CDC25B
DMDM Disease mutations994
Blocks (Seattle)CDC25B
PDB (RSDB)1CWR    1CWS    1CWT    1QB0    1YM9    1YMD    1YMK    1YML    1YS0    2A2K    2IFD    2IFV    2UZQ    3FQT    3FQU    4WH7    4WH9   
PDB Europe1CWR    1CWS    1CWT    1QB0    1YM9    1YMD    1YMK    1YML    1YS0    2A2K    2IFD    2IFV    2UZQ    3FQT    3FQU    4WH7    4WH9   
PDB (PDBSum)1CWR    1CWS    1CWT    1QB0    1YM9    1YMD    1YMK    1YML    1YS0    2A2K    2IFD    2IFV    2UZQ    3FQT    3FQU    4WH7    4WH9   
PDB (IMB)1CWR    1CWS    1CWT    1QB0    1YM9    1YMD    1YMK    1YML    1YS0    2A2K    2IFD    2IFV    2UZQ    3FQT    3FQU    4WH7    4WH9   
Structural Biology KnowledgeBase1CWR    1CWS    1CWT    1QB0    1YM9    1YMD    1YMK    1YML    1YS0    2A2K    2IFD    2IFV    2UZQ    3FQT    3FQU    4WH7    4WH9   
SCOP (Structural Classification of Proteins)1CWR    1CWS    1CWT    1QB0    1YM9    1YMD    1YMK    1YML    1YS0    2A2K    2IFD    2IFV    2UZQ    3FQT    3FQU    4WH7    4WH9   
CATH (Classification of proteins structures)1CWR    1CWS    1CWT    1QB0    1YM9    1YMD    1YMK    1YML    1YS0    2A2K    2IFD    2IFV    2UZQ    3FQT    3FQU    4WH7    4WH9   
SuperfamilyP30305
Human Protein Atlas [tissue]ENSG00000101224-CDC25B [tissue]
Peptide AtlasP30305
HPRD00307
IPIIPI00291990   IPI00216511   IPI00291992   IPI00029734   IPI01011807   IPI00910669   IPI00002089   
Protein Interaction databases
DIP (DOE-UCLA)P30305
IntAct (EBI)P30305
FunCoupENSG00000101224
BioGRIDCDC25B
STRING (EMBL)CDC25B
ZODIACCDC25B
Ontologies - Pathways
QuickGOP30305
Ontology : AmiGOG2/M transition of mitotic cell cycle  G2/M transition of mitotic cell cycle  mitotic cell cycle  spindle pole  oocyte maturation  phosphoprotein phosphatase activity  protein tyrosine phosphatase activity  protein tyrosine phosphatase activity  protein binding  nucleus  nucleoplasm  cytoplasm  centrosome  cytosol  protein phosphorylation  female meiosis I  positive regulation of cell proliferation  positive regulation of G2/M transition of mitotic cell cycle  protein kinase binding  positive regulation of cytokinesis  peptidyl-tyrosine dephosphorylation  positive regulation of protein kinase activity  positive regulation of mitotic cell cycle  positive regulation of mitotic cell cycle  cell division  positive regulation of G2/MI transition of meiotic cell cycle  
Ontology : EGO-EBIG2/M transition of mitotic cell cycle  G2/M transition of mitotic cell cycle  mitotic cell cycle  spindle pole  oocyte maturation  phosphoprotein phosphatase activity  protein tyrosine phosphatase activity  protein tyrosine phosphatase activity  protein binding  nucleus  nucleoplasm  cytoplasm  centrosome  cytosol  protein phosphorylation  female meiosis I  positive regulation of cell proliferation  positive regulation of G2/M transition of mitotic cell cycle  protein kinase binding  positive regulation of cytokinesis  peptidyl-tyrosine dephosphorylation  positive regulation of protein kinase activity  positive regulation of mitotic cell cycle  positive regulation of mitotic cell cycle  cell division  positive regulation of G2/MI transition of meiotic cell cycle  
Pathways : KEGGMAPK signaling pathway    Cell cycle    Progesterone-mediated oocyte maturation    MicroRNAs in cancer   
NDEx NetworkCDC25B
Atlas of Cancer Signalling NetworkCDC25B
Wikipedia pathwaysCDC25B
Orthology - Evolution
OrthoDB994
GeneTree (enSembl)ENSG00000101224
Phylogenetic Trees/Animal Genes : TreeFamCDC25B
HOGENOMP30305
Homologs : HomoloGeneCDC25B
Homology/Alignments : Family Browser (UCSC)CDC25B
Gene fusions - Rearrangements
Fusion : QuiverCDC25B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCDC25B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CDC25B
dbVarCDC25B
ClinVarCDC25B
1000_GenomesCDC25B 
Exome Variant ServerCDC25B
ExAC (Exome Aggregation Consortium)ENSG00000101224
GNOMAD BrowserENSG00000101224
Varsome BrowserCDC25B
Genetic variants : HAPMAP994
Genomic Variants (DGV)CDC25B [DGVbeta]
DECIPHERCDC25B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCDC25B 
Mutations
ICGC Data PortalCDC25B 
TCGA Data PortalCDC25B 
Broad Tumor PortalCDC25B
OASIS PortalCDC25B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCDC25B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCDC25B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CDC25B
DgiDB (Drug Gene Interaction Database)CDC25B
DoCM (Curated mutations)CDC25B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CDC25B (select a term)
intoGenCDC25B
Cancer3DCDC25B(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM116949   
Orphanet
DisGeNETCDC25B
MedgenCDC25B
Genetic Testing Registry CDC25B
NextProtP30305 [Medical]
TSGene994
GENETestsCDC25B
Target ValidationCDC25B
Huge Navigator CDC25B [HugePedia]
snp3D : Map Gene to Disease994
BioCentury BCIQCDC25B
ClinGenCDC25B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD994
Chemical/Pharm GKB GenePA26260
Clinical trialCDC25B
Miscellaneous
canSAR (ICR)CDC25B (select the gene name)
DataMed IndexCDC25B
Probes
Litterature
PubMed135 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCDC25B
EVEXCDC25B
GoPubMedCDC25B
iHOPCDC25B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Jan 17 18:05:28 CET 2019

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