N4BP1 (NEDD4 binding protein 1)

1. Identity

Other alias
General Information
HGNC (Hugo) N4BP1
LocusID (NCBI) 9683
Atlas_Id 70649
Location 16q12.1  [Link to chromosome band 16q12]
Location_base_pair Starts at 48538726 and ends at 48610209 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
N4BP1 (16q12.1) / N4BP1 (16q12.1)N4BP1 (16q12.1) / NFE2L2 (2q31.2)NOA1 (4q12) / N4BP1 (16q12.1)
PTPRA (20p13) / N4BP1 (16q12.1)PTPRA N4BP1C4orf14 N4BP1

2. DNA/RNA

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]
  t(4;16)(q12;q12) NOA1/N4BP1
t(16;20)(q12;p13) PTPRA/N4BP1

3. External links

Nomenclature
HGNC (Hugo)N4BP1   29850
Cards
Entrez_Gene (NCBI)N4BP1  9683  NEDD4 binding protein 1
Aliases
GeneCards (Weizmann)N4BP1
Ensembl hg19 (Hinxton)ENSG00000102921 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000102921 [Gene_View] &nbspENSG00000102921 [Sequence]  chr16:48538726-48610209 [Contig_View]  N4BP1 [Vega]
ICGC DataPortalENSG00000102921
TCGA cBioPortalN4BP1
AceView (NCBI)N4BP1
Genatlas (Paris)N4BP1
WikiGenes9683
SOURCE (Princeton)N4BP1
Genetics Home Reference (NIH)N4BP1
Genomic and cartography
GoldenPath hg38 (UCSC)N4BP1  -     chr16:48538726-48610209 -  16q12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)N4BP1  -     16q12.1   [Description]    (hg19-Feb_2009)
EnsemblN4BP1 - 16q12.1 [CytoView hg19]  N4BP1 - 16q12.1 [CytoView hg38]
Mapping of homologs : NCBIN4BP1 [Mapview hg19]  N4BP1 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AB014515 AK001464 AK026937 AK056383 AK094234
RefSeq transcript (Entrez)NM_153029
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)N4BP1
Cluster EST : UnigeneHs.511839 [ NCBI ]
CGAP (NCI)Hs.511839
Alternative Splicing GalleryENSG00000102921
Gene ExpressionN4BP1 [ NCBI-GEO ]   N4BP1 [ EBI - ARRAY_EXPRESS ]   N4BP1 [ SEEK ]   N4BP1 [ MEM ]
Gene Expression Viewer (FireBrowse)N4BP1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets] &nbsp [Normal Tissue Atlas] &nbsp[carcinoma Classsification] &nbsp[NCI60]
GenevestigatorExpression in : [tissues] &nbsp[cell-lines] &nbsp[cancer] &nbsp[perturbations] &nbsp
BioGPS (Tissue expression)9683
GTEX Portal (Tissue expression)N4BP1
Human Protein AtlasENSG00000102921-N4BP1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75113   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75113  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75113
Splice isoforms : SwissVarO75113
PhosPhoSitePlusO75113
Domains : Interpro (EBI)RNase_Zc3h12_NYN   
Domain families : Pfam (Sanger)RNase_Zc3h12a (PF11977)   
Domain families : Pfam (NCBI)pfam11977   
Conserved Domain (NCBI)N4BP1
DMDM Disease mutations9683
Blocks (Seattle)N4BP1
SuperfamilyO75113
Human Protein Atlas [tissue]ENSG00000102921-N4BP1 [tissue]
Peptide AtlasO75113
HPRD08109
IPIIPI00005667   
Protein Interaction databases
DIP (DOE-UCLA)O75113
IntAct (EBI)O75113
FunCoupENSG00000102921
BioGRIDN4BP1
STRING (EMBL)N4BP1
ZODIACN4BP1
Ontologies - Pathways
QuickGOO75113
Ontology : AmiGOprotein binding  nucleolus  PML body  negative regulation of protein ubiquitination  negative regulation of proteasomal ubiquitin-dependent protein catabolic process  cellular response to UV  
Ontology : EGO-EBIprotein binding  nucleolus  PML body  negative regulation of protein ubiquitination  negative regulation of proteasomal ubiquitin-dependent protein catabolic process  cellular response to UV  
NDEx NetworkN4BP1
Atlas of Cancer Signalling NetworkN4BP1
Wikipedia pathwaysN4BP1
Orthology - Evolution
OrthoDB9683
GeneTree (enSembl)ENSG00000102921
Phylogenetic Trees/Animal Genes : TreeFamN4BP1
HOVERGENO75113
HOGENOMO75113
Homologs : HomoloGeneN4BP1
Homology/Alignments : Family Browser (UCSC)N4BP1
Gene fusions - Rearrangements
Fusion PortalPTPRA N4BP1
Fusion PortalC4orf14 N4BP1
Fusion : QuiverN4BP1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerN4BP1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)N4BP1
dbVarN4BP1
ClinVarN4BP1
1000_GenomesN4BP1 
Exome Variant ServerN4BP1
ExAC (Exome Aggregation Consortium)ENSG00000102921
GNOMAD BrowserENSG00000102921
Varsome BrowserN4BP1
Genetic variants : HAPMAP9683
Genomic Variants (DGV)N4BP1 [DGVbeta]
DECIPHERN4BP1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisN4BP1 
Mutations
ICGC Data PortalN4BP1 
TCGA Data PortalN4BP1 
Broad Tumor PortalN4BP1
OASIS PortalN4BP1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICN4BP1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDN4BP1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch N4BP1
DgiDB (Drug Gene Interaction Database)N4BP1
DoCM (Curated mutations)N4BP1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)N4BP1 (select a term)
intoGenN4BP1
Cancer3DN4BP1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETN4BP1
MedgenN4BP1
Genetic Testing Registry N4BP1
NextProtO75113 [Medical]
TSGene9683
GENETestsN4BP1
Target ValidationN4BP1
Huge Navigator N4BP1 [HugePedia]
snp3D : Map Gene to Disease9683
BioCentury BCIQN4BP1
ClinGenN4BP1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9683
Chemical/Pharm GKB GenePA162396561
Clinical trialN4BP1
Miscellaneous
canSAR (ICR)N4BP1 (select the gene name)
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineN4BP1
EVEXN4BP1
GoPubMedN4BP1
iHOPN4BP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Jul 30 14:19:16 CEST 2018

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