OR4C46 (olfactory receptor family 4 subfamily C member 46)

1. Identity

Alias_names
General Information
Other alias-
HGNC (Hugo) OR4C46
LocusID (NCBI) 119749
Atlas_Id 54517
Location 11q11  [Link to chromosome band 11q11]
Location_base_pair Starts at 54603069 and ends at 54603998 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
OR9Q1 (11q12.1) / OR4C46 (11p11.12)

2. DNA/RNA

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]
  Lung: Translocations in Squamous Cell Carcinoma
t(11;11)(p11;q12) OR9Q1/OR4C46

3. External links

Nomenclature
HGNC (Hugo)OR4C46   31271
Cards
Entrez_Gene (NCBI)OR4C46  119749  olfactory receptor family 4 subfamily C member 46
Aliases
GeneCards (Weizmann)OR4C46
Ensembl hg19 (Hinxton)ENSG00000185926 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000185926 [Gene_View] &nbspENSG00000185926 [Sequence]  chr11:54603069-54603998 [Contig_View]  OR4C46 [Vega]
ICGC DataPortalENSG00000185926
TCGA cBioPortalOR4C46
AceView (NCBI)OR4C46
Genatlas (Paris)OR4C46
WikiGenes119749
SOURCE (Princeton)OR4C46
Genetics Home Reference (NIH)OR4C46
Genomic and cartography
GoldenPath hg38 (UCSC)OR4C46  -     chr11:54603069-54603998 -  11q11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)OR4C46  -     11q11   [Description]    (hg19-Feb_2009)
EnsemblOR4C46 - 11q11 [CytoView hg19]  OR4C46 - 11q11 [CytoView hg38]
Mapping of homologs : NCBIOR4C46 [Mapview hg19]  OR4C46 [Mapview hg38]
OMIM614273   
Gene and transcription
Genbank (Entrez)-
RefSeq transcript (Entrez)NM_001004703
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)OR4C46
Cluster EST : UnigeneHs.553564 [ NCBI ]
CGAP (NCI)Hs.553564
Alternative Splicing GalleryENSG00000185926
Gene ExpressionOR4C46 [ NCBI-GEO ]   OR4C46 [ EBI - ARRAY_EXPRESS ]   OR4C46 [ SEEK ]   OR4C46 [ MEM ]
Gene Expression Viewer (FireBrowse)OR4C46 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets] &nbsp [Normal Tissue Atlas] &nbsp[carcinoma Classsification] &nbsp[NCI60]
GenevestigatorExpression in : [tissues] &nbsp[cell-lines] &nbsp[cancer] &nbsp[perturbations] &nbsp
BioGPS (Tissue expression)119749
GTEX Portal (Tissue expression)OR4C46
Human Protein AtlasENSG00000185926-OR4C46 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtA6NHA9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtA6NHA9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProA6NHA9
Splice isoforms : SwissVarA6NHA9
PhosPhoSitePlusA6NHA9
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM    Olfact_rcpt   
Domain families : Pfam (Sanger)7tm_4 (PF13853)   
Domain families : Pfam (NCBI)pfam13853   
Conserved Domain (NCBI)OR4C46
DMDM Disease mutations119749
Blocks (Seattle)OR4C46
SuperfamilyA6NHA9
Human Protein Atlas [tissue]ENSG00000185926-OR4C46 [tissue]
Peptide AtlasA6NHA9
HPRD14964
IPIIPI00050342   
Protein Interaction databases
DIP (DOE-UCLA)A6NHA9
IntAct (EBI)A6NHA9
FunCoupENSG00000185926
BioGRIDOR4C46
STRING (EMBL)OR4C46
ZODIACOR4C46
Ontologies - Pathways
QuickGOA6NHA9
Ontology : AmiGOG protein-coupled receptor activity  olfactory receptor activity  plasma membrane  G protein-coupled receptor signaling pathway  integral component of membrane  detection of chemical stimulus involved in sensory perception of smell  
Ontology : EGO-EBIG protein-coupled receptor activity  olfactory receptor activity  plasma membrane  G protein-coupled receptor signaling pathway  integral component of membrane  detection of chemical stimulus involved in sensory perception of smell  
Pathways : KEGGOlfactory transduction   
NDEx NetworkOR4C46
Atlas of Cancer Signalling NetworkOR4C46
Wikipedia pathwaysOR4C46
Orthology - Evolution
OrthoDB119749
GeneTree (enSembl)ENSG00000185926
Phylogenetic Trees/Animal Genes : TreeFamOR4C46
HOGENOMA6NHA9
Homologs : HomoloGeneOR4C46
Homology/Alignments : Family Browser (UCSC)OR4C46
Gene fusions - Rearrangements
Fusion : MitelmanOR9Q1/OR4C46 [11q12.1/11p11.12] &nbsp[t(11;11)(p11;q12)]  
Fusion : QuiverOR4C46
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerOR4C46 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)OR4C46
dbVarOR4C46
ClinVarOR4C46
1000_GenomesOR4C46 
Exome Variant ServerOR4C46
ExAC (Exome Aggregation Consortium)ENSG00000185926
GNOMAD BrowserENSG00000185926
Varsome BrowserOR4C46
Genetic variants : HAPMAP119749
Genomic Variants (DGV)OR4C46 [DGVbeta]
DECIPHEROR4C46 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisOR4C46 
Mutations
ICGC Data PortalOR4C46 
TCGA Data PortalOR4C46 
Broad Tumor PortalOR4C46
OASIS PortalOR4C46 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICOR4C46  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDOR4C46
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch OR4C46
DgiDB (Drug Gene Interaction Database)OR4C46
DoCM (Curated mutations)OR4C46 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)OR4C46 (select a term)
intoGenOR4C46
Cancer3DOR4C46(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614273   
Orphanet
DisGeNETOR4C46
MedgenOR4C46
Genetic Testing Registry OR4C46
NextProtA6NHA9 [Medical]
TSGene119749
GENETestsOR4C46
Target ValidationOR4C46
Huge Navigator OR4C46 [HugePedia]
snp3D : Map Gene to Disease119749
BioCentury BCIQOR4C46
ClinGenOR4C46
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD119749
Chemical/Pharm GKB GenePA134910149
Clinical trialOR4C46
Miscellaneous
canSAR (ICR)OR4C46 (select the gene name)
DataMed IndexOR4C46
Probes
Litterature
PubMed3 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineOR4C46
EVEXOR4C46
GoPubMedOR4C46
iHOPOR4C46
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Jan 17 18:29:05 CET 2019

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