POP4 (POP4 homolog, ribonuclease P/MRP subunit)

1. Identity

Alias_names
General Information
Alias_symbol (synonym)RPP29
Other alias
HGNC (Hugo) POP4
LocusID (NCBI) 10775
Atlas_Id 72075
Location 19q12  [Link to chromosome band 19q12]
Location_base_pair Starts at 29606263 and ends at 29617255 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
EYA3 (1p35.3) / POP4 (19q12)POP4 (19q12) / LCN2 (9q34.11)

2. DNA/RNA

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(1;19)(p35;q12) EYA3/POP4


3. External links

Nomenclature
HGNC (Hugo)POP4   30081
Cards
Entrez_Gene (NCBI)POP4  10775  POP4 homolog, ribonuclease P/MRP subunit
AliasesRPP29
GeneCards (Weizmann)POP4
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View] &nbsp [Sequence]  chr19:29606263-29617255 [Contig_View]  POP4 [Vega]
TCGA cBioPortalPOP4
AceView (NCBI)POP4
Genatlas (Paris)POP4
WikiGenes10775
SOURCE (Princeton)POP4
Genetics Home Reference (NIH)POP4
Genomic and cartography
GoldenPath hg38 (UCSC)POP4  -     chr19:29606263-29617255 +  19q12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)POP4  -     19q12   [Description]    (hg19-Feb_2009)
EnsemblPOP4 - 19q12 [CytoView hg19]  POP4 - 19q12 [CytoView hg38]
Mapping of homologs : NCBIPOP4 [Mapview hg19]  POP4 [Mapview hg38]
OMIM606114   
Gene and transcription
Genbank (Entrez)AF001176 AK303791 AK314790 BC004438 BC006098
RefSeq transcript (Entrez)NM_006627
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)POP4
Cluster EST : UnigeneHs.412870 [ NCBI ]
CGAP (NCI)Hs.412870
Gene ExpressionPOP4 [ NCBI-GEO ]   POP4 [ EBI - ARRAY_EXPRESS ]   POP4 [ SEEK ]   POP4 [ MEM ]
Gene Expression Viewer (FireBrowse)POP4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets] &nbsp [Normal Tissue Atlas] &nbsp[carcinoma Classsification] &nbsp[NCI60]
GenevestigatorExpression in : [tissues] &nbsp[cell-lines] &nbsp[cancer] &nbsp[perturbations] &nbsp
BioGPS (Tissue expression)10775
GTEX Portal (Tissue expression)POP4
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95707   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95707  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95707
Splice isoforms : SwissVarO95707
PhosPhoSitePlusO95707
Domains : Interpro (EBI)RNase_P/MRP_p29    RNase_P/MRP_p29-subunit    Rof/RNase_P-like   
Domain families : Pfam (Sanger)UPF0086 (PF01868)   
Domain families : Pfam (NCBI)pfam01868   
Domain families : Smart (EMBL)POP4 (SM00538)  
Conserved Domain (NCBI)POP4
DMDM Disease mutations10775
Blocks (Seattle)POP4
SuperfamilyO95707
Peptide AtlasO95707
HPRD09358
IPIIPI00032791   IPI00908894   
Protein Interaction databases
DIP (DOE-UCLA)O95707
IntAct (EBI)O95707
BioGRIDPOP4
STRING (EMBL)POP4
ZODIACPOP4
Ontologies - Pathways
QuickGOO95707
Ontology : AmiGO###############################################################################################################################################################################################################################################################                            
Ontology : EGO-EBI###############################################################################################################################################################################################################################################################                            
NDEx NetworkPOP4
Atlas of Cancer Signalling NetworkPOP4
Wikipedia pathwaysPOP4
Orthology - Evolution
OrthoDB10775
Phylogenetic Trees/Animal Genes : TreeFamPOP4
HOVERGENO95707
HOGENOMO95707
Homologs : HomoloGenePOP4
Homology/Alignments : Family Browser (UCSC)POP4
Gene fusions - Rearrangements
Fusion : QuiverPOP4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPOP4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)POP4
dbVarPOP4
ClinVarPOP4
1000_GenomesPOP4 
Exome Variant ServerPOP4
Varsome BrowserPOP4
Genetic variants : HAPMAP10775
Genomic Variants (DGV)POP4 [DGVbeta]
DECIPHERPOP4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPOP4 
Mutations
ICGC Data PortalPOP4 
TCGA Data PortalPOP4 
Broad Tumor PortalPOP4
OASIS PortalPOP4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPOP4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPOP4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch POP4
DgiDB (Drug Gene Interaction Database)POP4
DoCM (Curated mutations)POP4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)POP4 (select a term)
intoGenPOP4
Cancer3DPOP4(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606114   
Orphanet
DisGeNETPOP4
MedgenPOP4
Genetic Testing Registry POP4
NextProtO95707 [Medical]
TSGene10775
GENETestsPOP4
Target ValidationPOP4
Huge Navigator POP4 [HugePedia]
snp3D : Map Gene to Disease10775
BioCentury BCIQPOP4
ClinGenPOP4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10775
Chemical/Pharm GKB GenePA134987921
Clinical trialPOP4
Miscellaneous
canSAR (ICR)POP4 (select the gene name)
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePOP4
EVEXPOP4
GoPubMedPOP4
iHOPPOP4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Jul 30 14:24:34 CEST 2018

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