RASAL3 (RAS protein activator like 3)

1. Identity

Alias_symbol (synonym)
General Information
Other alias-
HGNC (Hugo) RASAL3
LocusID (NCBI) 64926
Atlas_Id 56468
Location 19p13.12  [Link to chromosome band 19p13]
Location_base_pair Starts at 15451625 and ends at 15464581 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
RASAL3 (19p13.12) / LOC145837 ()

2. DNA/RNA

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

 


3. External links

Nomenclature
HGNC (Hugo)RASAL3   26129
Cards
Entrez_Gene (NCBI)RASAL3  64926  RAS protein activator like 3
Aliases
GeneCards (Weizmann)RASAL3
Ensembl hg19 (Hinxton)ENSG00000105122 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000105122 [Gene_View] &nbspENSG00000105122 [Sequence]  chr19:15451625-15464581 [Contig_View]  RASAL3 [Vega]
ICGC DataPortalENSG00000105122
TCGA cBioPortalRASAL3
AceView (NCBI)RASAL3
Genatlas (Paris)RASAL3
WikiGenes64926
SOURCE (Princeton)RASAL3
Genetics Home Reference (NIH)RASAL3
Genomic and cartography
GoldenPath hg38 (UCSC)RASAL3  -     chr19:15451625-15464581 -  19p13.12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RASAL3  -     19p13.12   [Description]    (hg19-Feb_2009)
EnsemblRASAL3 - 19p13.12 [CytoView hg19]  RASAL3 - 19p13.12 [CytoView hg38]
Mapping of homologs : NCBIRASAL3 [Mapview hg19]  RASAL3 [Mapview hg38]
OMIM616561   
Gene and transcription
Genbank (Entrez)AK024488 AK025091 AK122587 AL561064 AL832868
RefSeq transcript (Entrez)NM_001348027 NM_001348028 NM_022904
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RASAL3
Cluster EST : UnigeneHs.136979 [ NCBI ]
CGAP (NCI)Hs.136979
Alternative Splicing GalleryENSG00000105122
Gene ExpressionRASAL3 [ NCBI-GEO ]   RASAL3 [ EBI - ARRAY_EXPRESS ]   RASAL3 [ SEEK ]   RASAL3 [ MEM ]
Gene Expression Viewer (FireBrowse)RASAL3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets] &nbsp [Normal Tissue Atlas] &nbsp[carcinoma Classsification] &nbsp[NCI60]
GenevestigatorExpression in : [tissues] &nbsp[cell-lines] &nbsp[cancer] &nbsp[perturbations] &nbsp
BioGPS (Tissue expression)64926
GTEX Portal (Tissue expression)RASAL3
Human Protein AtlasENSG00000105122-RASAL3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86YV0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86YV0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86YV0
Splice isoforms : SwissVarQ86YV0
PhosPhoSitePlusQ86YV0
Domaine pattern : Prosite (Expaxy)RAS_GTPASE_ACTIV_1 (PS00509)    RAS_GTPASE_ACTIV_2 (PS50018)   
Domains : Interpro (EBI)C2_domain_sf    RasGAP_CS    RasGAP_dom    Rho_GTPase_activation_prot   
Domain families : Pfam (Sanger)RasGAP (PF00616)   
Domain families : Pfam (NCBI)pfam00616   
Domain families : Smart (EMBL)RasGAP (SM00323)  
Conserved Domain (NCBI)RASAL3
DMDM Disease mutations64926
Blocks (Seattle)RASAL3
SuperfamilyQ86YV0
Human Protein Atlas [tissue]ENSG00000105122-RASAL3 [tissue]
Peptide AtlasQ86YV0
IPIIPI00329668   IPI00893992   
Protein Interaction databases
DIP (DOE-UCLA)Q86YV0
IntAct (EBI)Q86YV0
FunCoupENSG00000105122
BioGRIDRASAL3
STRING (EMBL)RASAL3
ZODIACRASAL3
Ontologies - Pathways
QuickGOQ86YV0
Ontology : AmiGOMAPK cascade  GTPase activator activity  cytoplasm  cytosol  cell cortex  membrane  positive regulation of GTPase activity  negative regulation of Ras protein signal transduction  positive regulation of NK T cell proliferation  extracellular exosome  cytoplasmic side of membrane  
Ontology : EGO-EBIMAPK cascade  GTPase activator activity  cytoplasm  cytosol  cell cortex  membrane  positive regulation of GTPase activity  negative regulation of Ras protein signal transduction  positive regulation of NK T cell proliferation  extracellular exosome  cytoplasmic side of membrane  
Pathways : KEGGRas signaling pathway   
NDEx NetworkRASAL3
Atlas of Cancer Signalling NetworkRASAL3
Wikipedia pathwaysRASAL3
Orthology - Evolution
OrthoDB64926
GeneTree (enSembl)ENSG00000105122
Phylogenetic Trees/Animal Genes : TreeFamRASAL3
HOGENOMQ86YV0
Homologs : HomoloGeneRASAL3
Homology/Alignments : Family Browser (UCSC)RASAL3
Gene fusions - Rearrangements
Fusion : QuiverRASAL3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRASAL3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RASAL3
dbVarRASAL3
ClinVarRASAL3
1000_GenomesRASAL3 
Exome Variant ServerRASAL3
ExAC (Exome Aggregation Consortium)ENSG00000105122
GNOMAD BrowserENSG00000105122
Varsome BrowserRASAL3
Genetic variants : HAPMAP64926
Genomic Variants (DGV)RASAL3 [DGVbeta]
DECIPHERRASAL3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRASAL3 
Mutations
ICGC Data PortalRASAL3 
TCGA Data PortalRASAL3 
Broad Tumor PortalRASAL3
OASIS PortalRASAL3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRASAL3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRASAL3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RASAL3
DgiDB (Drug Gene Interaction Database)RASAL3
DoCM (Curated mutations)RASAL3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RASAL3 (select a term)
intoGenRASAL3
Cancer3DRASAL3(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616561   
Orphanet
DisGeNETRASAL3
MedgenRASAL3
Genetic Testing Registry RASAL3
NextProtQ86YV0 [Medical]
TSGene64926
GENETestsRASAL3
Target ValidationRASAL3
Huge Navigator RASAL3 [HugePedia]
snp3D : Map Gene to Disease64926
BioCentury BCIQRASAL3
ClinGenRASAL3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD64926
Chemical/Pharm GKB GenePA164725297
Clinical trialRASAL3
Miscellaneous
canSAR (ICR)RASAL3 (select the gene name)
DataMed IndexRASAL3
Probes
Litterature
PubMed7 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRASAL3
EVEXRASAL3
GoPubMedRASAL3
iHOPRASAL3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Jan 17 18:34:33 CET 2019

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