RPS10 (ribosomal protein S10)

1. Identity

Alias_symbol (synonym)
General Information
S10
Other aliasDBA9
HGNC (Hugo) RPS10
LocusID (NCBI) 6204
Atlas_Id 42160
Location 6p21.31  [Link to chromosome band 6p21]
Location_base_pair Starts at 34417454 and ends at 34426125 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
RPS10 (6p21.31) / EMC1 (1p36.13)RPS10 (6p21.31) / HPR (16q22.2)

2. DNA/RNA

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Prostate tumors: an overview

Other Cancer prone implicated (Data extracted from papers in the Atlas) [ 1 ]
  Diamond-Blackfan anemia (DBA)

3. External links

Nomenclature
HGNC (Hugo)RPS10   10383
LRG (Locus Reference Genomic)LRG_1138
Cards
Entrez_Gene (NCBI)RPS10  6204  ribosomal protein S10
AliasesDBA9; S10
GeneCards (Weizmann)RPS10
Ensembl hg19 (Hinxton)ENSG00000124614 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000124614 [Gene_View] &nbspENSG00000124614 [Sequence]  chr6:34417454-34426125 [Contig_View]  RPS10 [Vega]
ICGC DataPortalENSG00000124614
TCGA cBioPortalRPS10
AceView (NCBI)RPS10
Genatlas (Paris)RPS10
WikiGenes6204
SOURCE (Princeton)RPS10
Genetics Home Reference (NIH)RPS10
Genomic and cartography
GoldenPath hg38 (UCSC)RPS10  -     chr6:34417454-34426125 -  6p21.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RPS10  -     6p21.31   [Description]    (hg19-Feb_2009)
EnsemblRPS10 - 6p21.31 [CytoView hg19]  RPS10 - 6p21.31 [CytoView hg38]
Mapping of homologs : NCBIRPS10 [Mapview hg19]  RPS10 [Mapview hg38]
OMIM603632   613308   
Gene and transcription
Genbank (Entrez)AB209165 AK311797 BC001032 BC005012 BC070235
RefSeq transcript (Entrez)NM_001014 NM_001203245 NM_001204091
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RPS10
Cluster EST : UnigeneHs.645317 [ NCBI ]
CGAP (NCI)Hs.645317
Alternative Splicing GalleryENSG00000124614
Gene ExpressionRPS10 [ NCBI-GEO ]   RPS10 [ EBI - ARRAY_EXPRESS ]   RPS10 [ SEEK ]   RPS10 [ MEM ]
Gene Expression Viewer (FireBrowse)RPS10 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets] &nbsp [Normal Tissue Atlas] &nbsp[carcinoma Classsification] &nbsp[NCI60]
GenevestigatorExpression in : [tissues] &nbsp[cell-lines] &nbsp[cancer] &nbsp[perturbations] &nbsp
BioGPS (Tissue expression)6204
GTEX Portal (Tissue expression)RPS10
Human Protein AtlasENSG00000124614-RPS10 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP46783   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP46783  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP46783
Splice isoforms : SwissVarP46783
PhosPhoSitePlusP46783
Domains : Interpro (EBI)Rps10    S10_plectin_N    WH-like_DNA-bd_sf   
Domain families : Pfam (Sanger)S10_plectin (PF03501)   
Domain families : Pfam (NCBI)pfam03501   
Conserved Domain (NCBI)RPS10
DMDM Disease mutations6204
Blocks (Seattle)RPS10
PDB (RSDB)4UG0    4V6X    5A2Q    5AJ0    5FLX    5LKS    5OA3    5T2C    5VYC    6EK0    6FEC   
PDB Europe4UG0    4V6X    5A2Q    5AJ0    5FLX    5LKS    5OA3    5T2C    5VYC    6EK0    6FEC   
PDB (PDBSum)4UG0    4V6X    5A2Q    5AJ0    5FLX    5LKS    5OA3    5T2C    5VYC    6EK0    6FEC   
PDB (IMB)4UG0    4V6X    5A2Q    5AJ0    5FLX    5LKS    5OA3    5T2C    5VYC    6EK0    6FEC   
Structural Biology KnowledgeBase4UG0    4V6X    5A2Q    5AJ0    5FLX    5LKS    5OA3    5T2C    5VYC    6EK0    6FEC   
SCOP (Structural Classification of Proteins)4UG0    4V6X    5A2Q    5AJ0    5FLX    5LKS    5OA3    5T2C    5VYC    6EK0    6FEC   
CATH (Classification of proteins structures)4UG0    4V6X    5A2Q    5AJ0    5FLX    5LKS    5OA3    5T2C    5VYC    6EK0    6FEC   
SuperfamilyP46783
Human Protein Atlas [tissue]ENSG00000124614-RPS10 [tissue]
Peptide AtlasP46783
HPRD04697
IPIIPI00008438   IPI00816715   IPI00749512   IPI00478810   
Protein Interaction databases
DIP (DOE-UCLA)P46783
IntAct (EBI)P46783
FunCoupENSG00000124614
BioGRIDRPS10
STRING (EMBL)RPS10
ZODIACRPS10
Ontologies - Pathways
QuickGOP46783
Ontology : AmiGOribosomal small subunit assembly  nuclear-transcribed mRNA catabolic process, nonsense-mediated decay  RNA binding  structural constituent of ribosome  protein binding  nucleoplasm  nucleolus  cytosol  cytosol  ribosome  focal adhesion  translation  translational initiation  SRP-dependent cotranslational protein targeting to membrane  membrane  cytosolic small ribosomal subunit  cytosolic small ribosomal subunit  cytosolic small ribosomal subunit  
Ontology : EGO-EBIribosomal small subunit assembly  nuclear-transcribed mRNA catabolic process, nonsense-mediated decay  RNA binding  structural constituent of ribosome  protein binding  nucleoplasm  nucleolus  cytosol  cytosol  ribosome  focal adhesion  translation  translational initiation  SRP-dependent cotranslational protein targeting to membrane  membrane  cytosolic small ribosomal subunit  cytosolic small ribosomal subunit  cytosolic small ribosomal subunit  
Pathways : KEGGRibosome   
NDEx NetworkRPS10
Atlas of Cancer Signalling NetworkRPS10
Wikipedia pathwaysRPS10
Orthology - Evolution
OrthoDB6204
GeneTree (enSembl)ENSG00000124614
Phylogenetic Trees/Animal Genes : TreeFamRPS10
HOGENOMP46783
Homologs : HomoloGeneRPS10
Homology/Alignments : Family Browser (UCSC)RPS10
Gene fusions - Rearrangements
Fusion : MitelmanRPS10/HPR [6p21.31/16q22.2] &nbsp
Fusion : QuiverRPS10
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRPS10 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RPS10
dbVarRPS10
ClinVarRPS10
1000_GenomesRPS10 
Exome Variant ServerRPS10
ExAC (Exome Aggregation Consortium)ENSG00000124614
GNOMAD BrowserENSG00000124614
Varsome BrowserRPS10
Genetic variants : HAPMAP6204
Genomic Variants (DGV)RPS10 [DGVbeta]
DECIPHERRPS10 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRPS10 
Mutations
ICGC Data PortalRPS10 
TCGA Data PortalRPS10 
Broad Tumor PortalRPS10
OASIS PortalRPS10 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRPS10  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRPS10
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Mendelian genes
LOVD (Leiden Open Variation Database)**PUBLIC** CCHMC Molecular Genetics Laboratory Mutation Database
LOVD (Leiden Open Variation Database)Diamond-Blackfan Anemia
BioMutasearch RPS10
DgiDB (Drug Gene Interaction Database)RPS10
DoCM (Curated mutations)RPS10 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RPS10 (select a term)
intoGenRPS10
Cancer3DRPS10(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603632    613308   
Orphanet429   
DisGeNETRPS10
MedgenRPS10
Genetic Testing Registry RPS10
NextProtP46783 [Medical]
TSGene6204
GENETestsRPS10
Target ValidationRPS10
Huge Navigator RPS10 [HugePedia]
snp3D : Map Gene to Disease6204
BioCentury BCIQRPS10
ClinGenRPS10 (curated)
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6204
Chemical/Pharm GKB GenePA34779
Clinical trialRPS10
Miscellaneous
canSAR (ICR)RPS10 (select the gene name)
DataMed IndexRPS10
Probes
Litterature
PubMed98 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRPS10
EVEXRPS10
GoPubMedRPS10
iHOPRPS10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Jan 17 18:36:07 CET 2019

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