ZNF385B (zinc finger protein 385B)

1. Identity

Alias_names
General Information
zinc finger protein 533
Alias_symbol (synonym)FLJ25270
Other alias
HGNC (Hugo) ZNF385B
LocusID (NCBI) 151126
Atlas_Id 53194
Location 2q31.2  [Link to chromosome band 2q31]
Location_base_pair Starts at 179441984 and ends at 179861505 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CENPP (9q22.31) / ZNF385B (2q31.2)HADHA (2p23.3) / ZNF385B (2q31.2)SESTD1 (2q31.2) / ZNF385B (2q31.2)
ZNF385B (2q31.2) / FKBP7 (2q31.2)ZNF385B (2q31.2) / FTL (19q13.33)ZNF385B (2q31.2) / SCG5 (15q13.3)
SESTD1 2q31.2 / ZNF385B 2q31.2ZNF385B 2q31.2 / FKBP7 2q31.2ZNF385B 2q31.2 / SCG5 15q13.3

2. DNA/RNA

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 3 ]
  SESTD1/ZNF385B (2q31)
ZNF385B/FKBP7 (2q31)
t(2;15)(q31;q13) ZNF385B/SCG5


3. External links

Nomenclature
HGNC (Hugo)ZNF385B   26332
Cards
Entrez_Gene (NCBI)ZNF385B  151126  zinc finger protein 385B
AliasesZNF533
GeneCards (Weizmann)ZNF385B
Ensembl hg19 (Hinxton)ENSG00000144331 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000144331 [Gene_View] &nbspENSG00000144331 [Sequence]  chr2:179441984-179861505 [Contig_View]  ZNF385B [Vega]
ICGC DataPortalENSG00000144331
TCGA cBioPortalZNF385B
AceView (NCBI)ZNF385B
Genatlas (Paris)ZNF385B
WikiGenes151126
SOURCE (Princeton)ZNF385B
Genetics Home Reference (NIH)ZNF385B
Genomic and cartography
GoldenPath hg38 (UCSC)ZNF385B  -     chr2:179441984-179861505 -  2q31.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ZNF385B  -     2q31.2   [Description]    (hg19-Feb_2009)
EnsemblZNF385B - 2q31.2 [CytoView hg19]  ZNF385B - 2q31.2 [CytoView hg38]
Mapping of homologs : NCBIZNF385B [Mapview hg19]  ZNF385B [Mapview hg38]
OMIM612344   
Gene and transcription
Genbank (Entrez)AK057999 AK096822 BC033042 BC038422 BC048123
RefSeq transcript (Entrez)NM_001113397 NM_001113398 NM_001282725 NM_001352808 NM_001352809 NM_001352810 NM_001352811 NM_001352812 NM_001352813 NM_001352814 NM_001352815 NM_001352816 NM_001352817 NM_152520
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ZNF385B
Cluster EST : UnigeneHs.655005 [ NCBI ]
CGAP (NCI)Hs.655005
Alternative Splicing GalleryENSG00000144331
Gene ExpressionZNF385B [ NCBI-GEO ]   ZNF385B [ EBI - ARRAY_EXPRESS ]   ZNF385B [ SEEK ]   ZNF385B [ MEM ]
Gene Expression Viewer (FireBrowse)ZNF385B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets] &nbsp [Normal Tissue Atlas] &nbsp[carcinoma Classsification] &nbsp[NCI60]
GenevestigatorExpression in : [tissues] &nbsp[cell-lines] &nbsp[cancer] &nbsp[perturbations] &nbsp
BioGPS (Tissue expression)151126
GTEX Portal (Tissue expression)ZNF385B
Human Protein AtlasENSG00000144331-ZNF385B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ569K4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ569K4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ569K4
Splice isoforms : SwissVarQ569K4
PhosPhoSitePlusQ569K4
Domains : Interpro (EBI)Matrin/U1-like-C_Znf_C2H2    Znf_C2H2_sf    Znf_C2H2_type   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)ZnF_C2H2 (SM00355)  ZnF_U1 (SM00451)  
Conserved Domain (NCBI)ZNF385B
DMDM Disease mutations151126
Blocks (Seattle)ZNF385B
SuperfamilyQ569K4
Human Protein Atlas [tissue]ENSG00000144331-ZNF385B [tissue]
Peptide AtlasQ569K4
HPRD15823
IPIIPI00329671   IPI00654579   IPI00654841   IPI00654732   IPI00916893   IPI00969226   IPI00917349   IPI00654664   
Protein Interaction databases
DIP (DOE-UCLA)Q569K4
IntAct (EBI)Q569K4
FunCoupENSG00000144331
BioGRIDZNF385B
STRING (EMBL)ZNF385B
ZODIACZNF385B
Ontologies - Pathways
QuickGOQ569K4
Ontology : AmiGOfibrillar center  p53 binding  nucleic acid binding  nucleus  nucleus  zinc ion binding  intrinsic apoptotic signaling pathway by p53 class mediator  
Ontology : EGO-EBIfibrillar center  p53 binding  nucleic acid binding  nucleus  nucleus  zinc ion binding  intrinsic apoptotic signaling pathway by p53 class mediator  
NDEx NetworkZNF385B
Atlas of Cancer Signalling NetworkZNF385B
Wikipedia pathwaysZNF385B
Orthology - Evolution
OrthoDB151126
GeneTree (enSembl)ENSG00000144331
Phylogenetic Trees/Animal Genes : TreeFamZNF385B
HOGENOMQ569K4
Homologs : HomoloGeneZNF385B
Homology/Alignments : Family Browser (UCSC)ZNF385B
Gene fusions - Rearrangements
Fusion : MitelmanSESTD1/ZNF385B [2q31.2/2q31.2] &nbsp[t(2;2)(q31;q31)]  
Fusion : MitelmanZNF385B/FKBP7 [2q31.2/2q31.2] &nbsp[t(2;2)(q31;q31)]  
Fusion : MitelmanZNF385B/SCG5 [2q31.2/15q13.3] &nbsp[t(2;15)(q31;q13)]  
Fusion PortalSESTD1 2q31.2 ZNF385B 2q31.2 BRCA
Fusion PortalZNF385B 2q31.2 FKBP7 2q31.2 HNSC
Fusion PortalZNF385B 2q31.2 SCG5 15q13.3 BRCA
Fusion : QuiverZNF385B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerZNF385B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ZNF385B
dbVarZNF385B
ClinVarZNF385B
1000_GenomesZNF385B 
Exome Variant ServerZNF385B
ExAC (Exome Aggregation Consortium)ENSG00000144331
GNOMAD BrowserENSG00000144331
Varsome BrowserZNF385B
Genetic variants : HAPMAP151126
Genomic Variants (DGV)ZNF385B [DGVbeta]
DECIPHERZNF385B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisZNF385B 
Mutations
ICGC Data PortalZNF385B 
TCGA Data PortalZNF385B 
Broad Tumor PortalZNF385B
OASIS PortalZNF385B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICZNF385B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDZNF385B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ZNF385B
DgiDB (Drug Gene Interaction Database)ZNF385B
DoCM (Curated mutations)ZNF385B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ZNF385B (select a term)
intoGenZNF385B
Cancer3DZNF385B(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612344   
Orphanet
DisGeNETZNF385B
MedgenZNF385B
Genetic Testing Registry ZNF385B
NextProtQ569K4 [Medical]
TSGene151126
GENETestsZNF385B
Target ValidationZNF385B
Huge Navigator ZNF385B [HugePedia]
snp3D : Map Gene to Disease151126
BioCentury BCIQZNF385B
ClinGenZNF385B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD151126
Chemical/Pharm GKB GenePA162410114
Clinical trialZNF385B
Miscellaneous
canSAR (ICR)ZNF385B (select the gene name)
DataMed IndexZNF385B
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineZNF385B
EVEXZNF385B
GoPubMedZNF385B
iHOPZNF385B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Jan 17 18:47:04 CET 2019

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