t(1;6)(p34;p21) MEAF6/PHF1

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Written08-2018Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

1. Identity

Atlas_Id 104461
Phylum Female organs: Uterus::
WHO/OMS Classification Female organs
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

2. Clinics and Pathology

Disease Uterus: Endometrial stromal sarcoma

3. Genes involved and Proteins

Gene NameMEAF6
Location 1p34.3

Gene NamePHF1
Location 6p21.32

4. Bibliography

Novel fusion of MYST/Esa1-associated factor 6 and PHF1 in endometrial stromal sarcoma
Panagopoulos I, Micci F, Thorsen J, Gorunova L, Eibak AM, Bjerkehagen B, Davidson B, Heim S
PLoS One 2012;7(6):e39354
PMID 22761769
MEAF6/PHF1 is a recurrent gene fusion in endometrial stromal sarcoma
Micci F, Gorunova L, Gatius S, Matias-Guiu X, Davidson B, Heim S, Panagopoulos I
Cancer Lett 2014 May 28;347(1):75-8
PMID 24530230

5. Translocations implicated (Data extracted from papers in the Atlas)

 t(1;6)(p34;p21) MEAF6/PHF1

6. External links

Mitelman database t(1;6)(p34;p21) [CaseList]     t(1;6)(p34;p21) [Transloc - MCList]   MEAF6/PHF1 Fusion - MCList]
COSMIC[ MEAF6 ]   [ PHF1 ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
Disease databaset(1;6)(p34;p21) MEAF6/PHF1
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Nov 28 16:30:40 CET 2018

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