t(1;7)(p36;q34) CLCN6/BRAF

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Written08-2018Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

1. Identity

Atlas_Id 104499
Phylum Nervous system: Central Nervous system::
WHO/OMS Classification Nervous system
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

2. Clinics and Pathology

Disease Central Nervous system: Astrocytoma, pilocytic/juvenile

3. Genes involved and Proteins

Gene NameCLCN6
Location 1p36.22

Gene NameBRAF
Location 7q34

4. Bibliography

Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma
Jones DT, Hutter B, Jäger N, Korshunov A, Kool M, Warnatz HJ, Zichner T, Lambert SR, Ryzhova M, Quang DA, Fontebasso AM, Stütz AM, Hutter S, Zuckermann M, Sturm D, Gronych J, Lasitschka B, Schmidt S, Seker-Cin H, Witt H, Sultan M, Ralser M, Northcott PA, Hovestadt V, Bender S, Pfaff E, Stark S, Faury D, Schwartzentruber J, Majewski J, Weber UD, Zapatka M, Raeder B, Schlesner M, Worth CL, Bartholomae CC, von Kalle C, Imbusch CD, Radomski S, Lawerenz C, van Sluis P, Koster J, Volckmann R, Versteeg R, Lehrach H, Monoranu C, Winkler B, Unterberg A, Herold-Mende C, Milde T, Kulozik AE, Ebinger M, Schuhmann MU, Cho YJ, Pomeroy SL, von Deimling A, Witt O, Taylor MD, Wolf S, Karajannis MA, Eberhart CG, Scheurlen W, Hasselblatt M, Ligon KL, Kieran MW, Korbel JO, Yaspo ML, Brors B, Felsberg J, Reifenberger G, Collins VP, Jabado N, Eils R, Lichter P, Pfister SM; International Cancer Genome Consortium PedBrain Tumor Project
Nat Genet 2013 Aug;45(8):927-32
PMID 23817572
 

5. Translocations implicated (Data extracted from papers in the Atlas)

 t(1;7)(p36;q34) CLCN6/BRAF

6. External links

Mitelman database t(1;7)(p36;q34) [CaseList]     t(1;7)(p36;q34) [Transloc - MCList]   CLCN6/BRAF Fusion - MCList]
COSMIC[ CLCN6 ]   [ BRAF ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
 
 
Disease databaset(1;7)(p36;q34) CLCN6/BRAF
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed


© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Nov 28 16:30:51 CET 2018

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