t(1;16)(p36;p12) PDPN/PRKCB

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Written08-2018Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

1. Identity

Atlas_Id 104210
Phylum Soft Tissues: Soft Tissues::
WHO/OMS Classification Soft Tissues
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

2. Clinics and Pathology

Disease Soft Tissues: Benign fibrous histiocytoma

3. Genes involved and Proteins

Gene NamePDPN
Location 1p36.21

Gene NamePRKCB
Location 16p12.2

4. Bibliography

Fusions involving protein kinase C and membrane-associated proteins in benign fibrous histiocytoma
Płaszczyca A, Nilsson J, Magnusson L, Brosjö O, Larsson O, Vult von Steyern F, Domanski HA, Lilljebjörn H, Fioretos T, Tayebwa J, Mandahl N, Nord KH, Mertens F
Int J Biochem Cell Biol 2014 Aug;53:475-81
PMID 24721208
 
Gene fusion detection in formalin-fixed paraffin-embedded benign fibrous histiocytomas using fluorescence in situ hybridization and RNA sequencing
Walther C, Hofvander J, Nilsson J, Magnusson L, Domanski HA, Gisselsson D, Tayebwa J, Doyle LA, Fletcher CD, Mertens F
Lab Invest 2015 Sep;95(9):1071-6
PMID 26121314
 


5. Translocations implicated (Data extracted from papers in the Atlas)

 t(1;16)(p36;p12) PDPN/PRKCB

6. External links

Mitelman database t(1;16)(p36;p12) [CaseList]     t(1;16)(p36;p12) [Transloc - MCList]   PDPN/PRKCB Fusion - MCList]
COSMIC[ PDPN ]   [ PRKCB ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
 
 
Disease databaset(1;16)(p36;p12) PDPN/PRKCB
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed


© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Nov 28 16:31:42 CET 2018

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