t(3;4)(q21;p12) MYLK/TXK

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA
Written08-2018Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

1. Identity

Atlas_Id 106106
Phylum Neuro-Endocrine/Endocrine system: Adrenal gland::
WHO/OMS Classification Neuro-Endocrine/Endocrine system
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

2. Clinics and Pathology

Disease Adrenal gland: Neuroblastoma

3. Genes involved and Proteins

Gene NameMYLK
Location 3q21.1

Gene NameTXK
Location 4p12

4. Bibliography

The genetic landscape of high-risk neuroblastoma
Pugh TJ, Morozova O, Attiyeh EF, Asgharzadeh S, Wei JS, Auclair D, Carter SL, Cibulskis K, Hanna M, Kiezun A, Kim J, Lawrence MS, Lichenstein L, McKenna A, Pedamallu CS, Ramos AH, Shefler E, Sivachenko A, Sougnez C, Stewart C, Ally A, Birol I, Chiu R, Corbett RD, Hirst M, Jackman SD, Kamoh B, Khodabakshi AH, Krzywinski M, Lo A, Moore RA, Mungall KL, Qian J, Tam A, Thiessen N, Zhao Y, Cole KA, Diamond M, Diskin SJ, Mosse YP, Wood AC, Ji L, Sposto R, Badgett T, London WB, Moyer Y, Gastier-Foster JM, Smith MA, Guidry Auvil JM, Gerhard DS, Hogarty MD, Jones SJ, Lander ES, Gabriel SB, Getz G, Seeger RC, Khan J, Marra MA, Meyerson M, Maris JM
Nat Genet 2013 Mar;45(3):279-84
PMID 23334666
 


5. Translocations implicated (Data extracted from papers in the Atlas)

 t(3;4)(q21;p12) MYLK/TXK

6. External links

Mitelman database t(3;4)(q21;p12) [CaseList]     t(3;4)(q21;p12) [Transloc - MCList]   MYLK/TXK Fusion - MCList]
COSMIC[ MYLK ]   [ TXK ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
 
 
Disease databaset(3;4)(q21;p12) MYLK/TXK
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed


© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Nov 28 16:37:02 CET 2018

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