t(11;22)(p11;q12) EWSR1/CREB3L1

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Written08-2018Jean-Loup Huret, Philippe Dessen

(Note : for Links provided by Atlas : click)

1. Identity

Atlas_Id 101077
Phylum Soft Tissues: Soft Tissues::
WHO/OMS Classification Soft Tissues
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

2. Clinics and Pathology

Disease Soft Tissues: Low-grade fibromyxoid sarcoma

Disease Soft Tissues: Sclerosing epithelioid fibrosarcoma

3. Genes involved and Proteins

Gene NameEWSR1
Location 22q12.2

Gene NameCREB3L1
Location 11p11.2

4. Bibliography

EWSR1-CREB3L1 gene fusion: a novel alternative molecular aberration of low-grade fibromyxoid sarcoma
Lau PP, Lui PC, Lau GT, Yau DT, Cheung ET, Chan JK
Am J Surg Pathol 2013 May;37(5):734-8
PMID 23588368
Inactivating mutations and overexpression of BCL10, a caspase recruitment domain-containing gene, in MALT lymphoma with t(1;14)(p22;q32)
Zhang Q, Siebert R, Yan M, Hinzmann B, Cui X, Xue L, Rakestraw KM, Naeve CW, Beckmann G, Weisenburger DD, Sanger WG, Nowotny H, Vesely M, Callet-Bauchu E, Salles G, Dixit VM, Rosenthal A, Schlegelberger B, Morris SW
Nat Genet 1999 May;22(1):63-8
PMID 10319863

5. Translocations implicated (Data extracted from papers in the Atlas)

 t(11;22)(p11;q12) EWSR1/CREB3L1

6. External links

Mitelman database t(11;22)(p11;q12) [CaseList]     t(11;22)(p11;q12) [Transloc - MCList]   EWSR1/CREB3L1 Fusion - MCList]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
Disease databaset(11;22)(p11;q12) EWSR1/CREB3L1
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Nov 28 16:55:37 CET 2018

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