Lung: Translocations in Squamous Cell Carcinoma

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Written2014-10Jean-Loup Huret
Genetics, Dept Medical Information, University of Poitiers, CHU Poitiers Hospital, F-86021 Poitiers, France

(Note : for Links provided by Atlas : click)

1. Identity

Atlas_Id 6819
Phylum Lung, Heart, Skin, Other::Squamous cell carcinoma
WHO/OMS Classification Lung, Heart, Skin, Other

2. Classification

    In the group of malignant epithelial tumours of the lungs, squamous cell carcinomas belong to the non-small cell carcinomas (non-small cell lung cancer (NSCLC)), as opposed to small cell carcinomas (SCLC). Other NSCLCs are: adenocarcinomas, adenosquamous carcinomas, large cell carcinomas, sarcomatoid carcinomas, carcinoid tumours, salivary gland tumours.

3. Clinics and Pathology

Epidemiology Squamous cell carcinoma is the most frequent lung cancer in male patients, representing about 40% of the cases, and only 25% in women (much less frequent in female patients than adenocarcinoma). Squamous cell carcinoma is the lung cancer the most often associated with tobacco smoking. Location of the tumour is usually central, present as a perihilar mass, with or without lobar collapse and obstructive pneumonitis, but it can also be peripheral at times.
Pathology There are small cell variants (differential diagnosis: SCLC), clear cell variants, well-differentiated papillary variants, basaloid variants with a very aggressive clinical course, and spindle cell (sarcomatoid) carcinosarcoma variants of the typical squamous cell carcinoma.
The expression of cytokeratins (CK) CK5/6, CK34BE12 and TP63 (3q28, also called P63) are strong in squamous cell carcinoma, whereas the expression of CK7 and NKX2-1 (14q13, also called TTF-1) are strong in adenocarcinoma (Xu et al., 2014).
Evolution Staging is performed according to the TNM system.

4. Genetics

Note TP53 (17p13) mutations are detected in most cases. In a large recent study, altered pathways included NFE2L2/KEAP1 in 34%, squamous differentiation genes in 44%, PI3K/AKT in 47%, and CDKN2A/RB1 in 72% of tumors. In contrast to what is found in adenocarcinoma, mutations in EGFR (7p11) or in KRAS (12p12) are extremely rare in squamous cell carcinoma of the lungs (Cancer Genome Atlas Research Network, 2012). DDR2 (1q23) is inactivated in about 4% of cases; FGFR1 (8p11) and FGFR3 (4p16) are amplified in 5 to 10% of cases (Majewski et al., 2013; Seo et al., 2014).

5. Cytogenetics

Note Of 157 translocations so far reported in squamous cell carcinoma of the lungs, 1 gene was found five times implicated: ATP11B (3q26, which catalyzes the hydrolysis of ATP); 1 gene was implicated in three different translocations: MCF2L2 (3q27, a guanine nucleotide exchange factor); and 13 genes were found twice: ANGPT1 (8q23), EIF4EBP1 (8p11), EML4 (2p21), IGF2 (11p15), ITSN1 (21q22), KLHL29 (2p24), MAN1A2 (1p13), MGAT5 (2q21), NPAS3 (14q13), PPP6R3 (14q13), ROS1 (6q22), TMCC1 ( 3q22), and TTC28 (22q12).
Finally, 280 genes were found implicated in one translocation.
Cytogenetics
Morphological
The translocations are the following:
t(1;1)(p36;p36) PRKCZ/SKI (Majewski et al., 2013)
t(1;1)(p34;q44) SMYD3/ELOVL1 (Cancer Genome Atlas Research Network, 2012)
t(1;1)(q21;q21) GATAD2B/PRKAB2 (Cancer Genome Atlas Research Network, 2012)
t(1;2)(p35;q37) ZBTB8B/TRAF3IP1 (Cancer Genome Atlas Research Network, 2012)
t(1;2)(p12;p16) REL/MAN1A2 (Cancer Genome Atlas Research Network, 2012)
t(1;2)(p12;p15) PHGDH/WDPCP (Cancer Genome Atlas Research Network, 2012)
t(1;3)(p34;q26) ATP11B/POU3F1 (Cancer Genome Atlas Research Network, 2012)
t(1;3)(p34;q26) OSCP1/SOX2-OT (Cancer Genome Atlas Research Network, 2012)
t(1;3)(p33;q29) TFRC/NSUN4 (Cancer Genome Atlas Research Network, 2012)
t(1;4)(p31;q22) BMPR1B/ALG6 (Cancer Genome Atlas Research Network, 2012)
t(1;5)(p34;q31) CTNNA1/HEYL (Cancer Genome Atlas Research Network, 2012)
t(1;5)(q25;p13) DARS2/ZFR (Cancer Genome Atlas Research Network, 2012)
t(1;8)(p36;q21) SLC7A13/WDTC1 (Cancer Genome Atlas Research Network, 2012)
t(1;8)(p32;q24) NRD1/KCNK9 (Cancer Genome Atlas Research Network, 2012)
t(1;9)(p33;p13) KIF24/FAAH (Cancer Genome Atlas Research Network, 2012)
t(1;10)(p32;q21) CDK1/USP24 (Cancer Genome Atlas Research Network, 2012)
t(1;10)(p31;p14) SFMBT2/PRKACB (Cancer Genome Atlas Research Network, 2012)
t(1;10)(q32;q22) TMEM206/PSAP (Cancer Genome Atlas Research Network, 2012)
t(1;11)(p31;q24) ETS1/NEGR1 (Cancer Genome Atlas Research Network, 2012)
t(1;12)(q25;p12) HMCN1/ETNK1 (Cancer Genome Atlas Research Network, 2012)
t(1;16)(q21;p12) CCP110/GOLPH3L (Cancer Genome Atlas Research Network, 2012)
t(1;17)(p21;q25) UNK/DPYD (Cancer Genome Atlas Research Network, 2012)
t(1;17)(p12;q11) ALDOC/MAN1A2 (Cancer Genome Atlas Research Network, 2012)
t(1;21)(p35;q22) ITSN1/MATN1 (Cancer Genome Atlas Research Network, 2012)
t(2;2)(p25;p25) ROCK2/SH3YL1 (Cancer Genome Atlas Research Network, 2012)
t(2;2)(p24;p23) GPN1/KLHL29 (Cancer Genome Atlas Research Network, 2012)
inv(2)(p21p23) or del(2)(p21p23) EML4/ALK (Rikova et al., 2007; Soda et al., 2007; Martelli et al., 2009)
t(2;2)(p21;p21) THADA/EML4 (Cancer Genome Atlas Research Network, 2012)
t(2;2)(p16;p23) PSME4/PPP1CB (Cancer Genome Atlas Research Network, 2012)
t(2;2)(p15;p15) EHBP1/FAM161A (Cancer Genome Atlas Research Network, 2012)
t(2;2)(q21;q21) GPR39/MGAT5 (Cancer Genome Atlas Research Network, 2012)
t(2;2)(q21;q24) ACVR1C/MGAT5 (Cancer Genome Atlas Research Network, 2012)
t(2;2)(q23;q35) TNS1/RPRM (Cancer Genome Atlas Research Network, 2012)
t(2;3)(p16;q26) KCNMB2/NRXN1 (Cancer Genome Atlas Research Network, 2012)
t(2;4)(p16;q13) BCL11A/EPHA5 (Cancer Genome Atlas Research Network, 2012)
t(2;5)(p16;p15) NRXN1/PLEKHG4B (Cancer Genome Atlas Research Network, 2012)
t(2;5)(p11;p12) HCN1/FUNDC2P2 (Cancer Genome Atlas Research Network, 2012)
t(2;5)(q35;p13) USP37/OSMR (Cancer Genome Atlas Research Network, 2012)
t(2;6)(p24;p22) ID4/FAM84A (Cancer Genome Atlas Research Network, 2012)
t(2;16)(q24;q11) ANKRD26P1/SLC4A10 (Cancer Genome Atlas Research Network, 2012)
t(2;17)(p25;q21) CRHR1-IT1/ALLC (Cancer Genome Atlas Research Network, 2012)
t(2;18)(p24;q11) KLHL29/PSMA8 (Cancer Genome Atlas Research Network, 2012)
t(2;22)(p12;q12) EVA1A/TTC28 (Cancer Genome Atlas Research Network, 2012)
t(3;3)(p12;q29) PAK2/VGLL3 (Cancer Genome Atlas Research Network, 2012)
t(3;3)(q11;q13) ALCAM/EPHA6 (Cancer Genome Atlas Research Network, 2012)
t(3;3)(q12;q13) GSK3B/IMPG2 (Cancer Genome Atlas Research Network, 2012)
t(3;3)(q13;q22) SLCO2A1/GUCA1C (Cancer Genome Atlas Research Network, 2012)
t(3;3)(q21;q22) RUVBL1/TMCC1 (Cancer Genome Atlas Research Network, 2012)
t(3;3)(q22;q22) PIK3CB/BFSP2 (Cancer Genome Atlas Research Network, 2012)
t(3;3)(q22;q22) TMCC1/C3orf36 (Cancer Genome Atlas Research Network, 2012)
t(3;3)(q24;q26) HLTF/OTOL1 (Cancer Genome Atlas Research Network, 2012)
t(3;3)(q25;q25) GMPS/C3orf55 (Cancer Genome Atlas Research Network, 2012)
t(3;3)(q25;q26) IQCJ/BCHE (Cancer Genome Atlas Research Network, 2012)
t(3;3)(q25;q27) PPM1L/MCF2L2 (Cancer Genome Atlas Research Network, 2012)
t(3;3)(q25;q28) PYDC2/C3orf79 (Cancer Genome Atlas Research Network, 2012)
t(3;3)(q26;q26) ATP11B/SI (Cancer Genome Atlas Research Network, 2012)
t(3;3)(q26;q26) PHC3/FNDC3B (Cancer Genome Atlas Research Network, 2012)
t(3;3)(q26;q27) CCDC39/MCF2L2 (Cancer Genome Atlas Research Network, 2012)
t(3;3)(q26;q28) SOX2/TPRG1 (Cancer Genome Atlas Research Network, 2012)
t(3;3)(q27;q28) LPP/ST6GAL1 (Cancer Genome Atlas Research Network, 2012)
t(3;3)(q27;q29) EHHADH/SENP5 (Cancer Genome Atlas Research Network, 2012)
t(3;3)(q29;q29) LRCH3/MIR570 (Cancer Genome Atlas Research Network, 2012)
t(3;4)(q26;p16) ATP11B/ZNF595 (Cancer Genome Atlas Research Network, 2012)
t(3;8)(q27;q22) MCF2L2/MIR548A3 (Cancer Genome Atlas Research Network, 2012)
t(3;8)(q29;p12) FYTTD1/WRN (Cancer Genome Atlas Research Network, 2012)
t(3;11)(q26;p15) PDE3B/ATP11B (Cancer Genome Atlas Research Network, 2012)
t(3;13)(q21;q33) TNFSF13B/MYLK (Cancer Genome Atlas Research Network, 2012)
t(3;17)(q25;p11) MAP2K3/SSR3 (Cancer Genome Atlas Research Network, 2012)
t(3;17)(q29;q23) MIR21/WDR53 (Cancer Genome Atlas Research Network, 2012)
t(3;19)(q27;q13) ACTN4/IGF2BP2 (Cancer Genome Atlas Research Network, 2012)
t(3;20)(q21;q13) SLC12A8/BCAS1 (Cancer Genome Atlas Research Network, 2012)
t(3;21)(p11;q21) POU1F1/TMPRSS15 (Cancer Genome Atlas Research Network, 2012)
t(3;22)(q26;q11) ATP11B/TPTEP1 (Cancer Genome Atlas Research Network, 2012)
del(4)(p16p16) FGFR3/TACC3 (Majewski et al., 2013; Wu et al. 2013)
t(4;4)(q13;q22) CCSER1/UGT2A1 (Cancer Genome Atlas Research Network, 2012)
t(4;6)(p15;q22) SLC34A2/ROS1 (Davies et al., 2012)
t(4;8)(q13;q24) COX18/ZFAT (Cancer Genome Atlas Research Network, 2012)
t(4;9)(q13;q32) ADAMTS3/SNX30 (Cancer Genome Atlas Research Network, 2012)
t(4;10)(p13;q11) SGMS1/KCTD8 (Cancer Genome Atlas Research Network, 2012)
t(5;5)(p15;p15) MARCH6/IRX4 (Cancer Genome Atlas Research Network, 2012)
t(5;5)(p15;p15) ROPN1L/SEMA5A (Cancer Genome Atlas Research Network, 2012)
t(5;5)(p12;p13) RICTOR/FGF10 (Cancer Genome Atlas Research Network, 2012)
t(5;6)(q33;q22) CD74/ROS1 (Davies et al., 2012)
t(5;8)(p15;q21) MRPS28/ADAMTS16 (Cancer Genome Atlas Research Network, 2012)
t(5;8)(p13;p11) EIF4EBP1/PRKAA1 (Cancer Genome Atlas Research Network, 2012)
t(5;11)(q14;q22) FAM151B/CASP12 (Cancer Genome Atlas Research Network, 2012)
t(5;11)(q35;q14) KCNIP1/KCTD14 (Cancer Genome Atlas Research Network, 2012)
t(5;12)(p12;q13) NNT/AMIGO2 (Cancer Genome Atlas Research Network, 2012)
t(6;6)(p25;p25) FAM50B/PPP1R3G (Cancer Genome Atlas Research Network, 2012)
t(6;6)(p22;q12) EYS/DEK (Cancer Genome Atlas Research Network, 2012)
t(6;6)(p21;p21) HLA-DOA/MUC21 (Cancer Genome Atlas Research Network, 2012)
t(6;6)(p12;p22) BEND6/TRIM38 (Cancer Genome Atlas Research Network, 2012)
t(6;6)(p12;q14) FAM83B/HTR1E (Cancer Genome Atlas Research Network, 2012)
t(6;6)(q14;q15) GABRR2/ME1 (Cancer Genome Atlas Research Network, 2012)
t(6;13)(p21;q12) RPL7L1/CDK8 (Cancer Genome Atlas Research Network, 2012)
t(6;14)(q24;q24) SASH1/DPF3 (Cancer Genome Atlas Research Network, 2012)
t(6;16)(q13;p13) NTAN1/SLC17A5 (Cancer Genome Atlas Research Network, 2012)
t(7;7)(p11;p12) VOPP1/GRB10 (Cancer Genome Atlas Research Network, 2012)
t(7;7)(q22;q31) ANKRD7/DUS4L (Cancer Genome Atlas Research Network, 2012)
t(7;7)(q31;q33) CHCHD3/MET (Cancer Genome Atlas Research Network, 2012)
t(7;8)(p14;p23) AMPH/FDFT1 (Majewski et al., 2013)
t(7;10)(q36;q25) ACTR3C/SORCS1 (Cancer Genome Atlas Research Network, 2012)
t(8;8)(p11;p11) ADAM9/RNF170 (Cancer Genome Atlas Research Network, 2012)
t(8;8)(p11;p11) BAG4/FGFR1 (Wu et al., 2013)
t(8;8)(p11;p11) LETM2/KCNU1 (Cancer Genome Atlas Research Network, 2012)
t(8;8)(q11;q11) PRKDC/C8orf22 (Cancer Genome Atlas Research Network, 2012)
t(8;8)(q23;q23) CSMD3/ANGPT1 (Cancer Genome Atlas Research Network, 2012)
t(8;8)(q23;q23) OXR1/RSPO2 (Cancer Genome Atlas Research Network, 2012)
t(8;9)(p12;p13) PURG/UBAP1 (Cancer Genome Atlas Research Network, 2012)
t(8;9)(p11;p21) EIF4EBP1/C9orf53 (Cancer Genome Atlas Research Network, 2012)
t(8;10)(p21;q26) FGFR2/KIAA1967 (Wu et al., 2013)
t(8;10)(q23;q11) ANGPT1/CXCL12 (Cancer Genome Atlas Research Network, 2012)
t(8;11)(q21;p15) HTATIP2/CA1 (Cancer Genome Atlas Research Network, 2012)
t(8;15)(q21;q21) NEDD4/RDH10 (Cancer Genome Atlas Research Network, 2012)
t(8;16)(p11;p12) KIAA0556/LSM1 (Cancer Genome Atlas Research Network, 2012)
t(8;16)(q22;q24) GSE1/NACAP1 (Cancer Genome Atlas Research Network, 2012)
t(8;21)(q11;q21) UBE2V2/NRIP1 (Cancer Genome Atlas Research Network, 2012)
t(9;9)(p21;p21) CDKN2A/FOCAD (Cancer Genome Atlas Research Network, 2012)
t(9;9)(p21;p13) PLAA/RUSC2 (Cancer Genome Atlas Research Network, 2012)
t(9;19)(p13;p13) FAM219A/S1PR5 (Cancer Genome Atlas Research Network, 2012)
inv(10)(p11q11) KIF5B/RET (Cai et al., 2013)
t(10;11)(q21;p15) CTNNA3/IGF2 (Cancer Genome Atlas Research Network, 2012)
t(10;11)(q22;q14) P4HA1/TRIM77P (Cancer Genome Atlas Research Network, 2012)
t(10;17)(q22;q12) SAMD8/LHX1 (Cancer Genome Atlas Research Network, 2012)
t(10;20)(q23;q13) WAPAL/PTPRT (Cancer Genome Atlas Research Network, 2012)
t(11;11)(p14;p13) EIF3M/MPPED2 (Cancer Genome Atlas Research Network, 2012)
t(11;11)(p11;q12) OR9Q1/OR4C46 (Cancer Genome Atlas Research Network, 2012)
t(11;11)(q12;q12) P2RX3/RTN4RL2 (Majewski et al., 2013)
t(11;11)(q12;q13) EEF1G/PPP6R3 (Cancer Genome Atlas Research Network, 2012)
t(11;11)(q12;q13) SHANK2/MS4A8B (Cancer Genome Atlas Research Network, 2012)
t(11;11)(q13;q22) PPP6R3/CNTN5 (Cancer Genome Atlas Research Network, 2012)
t(11;12)(p11;p13) ERC1/SPI1 (Cancer Genome Atlas Research Network, 2012)
t(12;20)(q12;q13) TAF4/ALG10B (Cancer Genome Atlas Research Network, 2012)
t(12;22)(q14;q12) SLC16A7/TTC28 (Cancer Genome Atlas Research Network, 2012)
t(13;20)(q12;p12) MACROD2/MPHOSPH8 (Cancer Genome Atlas Research Network, 2012)
t(14;14)(q11;q13) NPAS3/OXA1L (Cancer Genome Atlas Research Network, 2012)
t(14;14)(q12;q13) FOXG1/NPAS3 (Cancer Genome Atlas Research Network, 2012)
t(14;14)(q13;q21) MBIP/C14orf183 (Cancer Genome Atlas Research Network, 2012)
t(14;14)(q13;q21) SEC23A/IGBP1P1 (Cancer Genome Atlas Research Network, 2012)
t(16;16)(q12;q13) FTO/HERPUD1 (Majewski et al., 2013)
t(16;16)(q23;q24) JPH3/OSGIN1 (Cancer Genome Atlas Research Network, 2012)
t(16;22)(p12;q11) POM121L4P/LCMT1 (Cancer Genome Atlas Research Network, 2012)
t(17;17)(p13;p11) PIGL/RABEP1 (Cancer Genome Atlas Research Network, 2012)
t(17;17)(p11;q11) AKAP10/PSMD11 (Cancer Genome Atlas Research Network, 2012)
t(17;17)(p11;q11) KIAA0100/ALKBH5 (Cancer Genome Atlas Research Network, 2012)
t(17;17)(q23;q23) RPS6KB1/VMP1 (Majewski et al., 2013)
t(18;22)(q12;q11) CDC45/RIT2 (Cancer Genome Atlas Research Network, 2012)
t(19;19)(p13;p12) UNC13A/ZNF492 (Cancer Genome Atlas Research Network, 2012)
t(19;19)(q13;q13) BCL3/HIPK4 (Cancer Genome Atlas Research Network, 2012)
t(19;19)(q13;q13) SIPA1L3/CD22 (Cancer Genome Atlas Research Network, 2012)
t(19;21)(p13;q22) ITSN1/ZNF490 (Cancer Genome Atlas Research Network, 2012)
t(19;22)(p12;q11) MMP11/ZNF714 (Cancer Genome Atlas Research Network, 2012)
t(20;20)(q11;q13) ADNP/DLGAP4 (Cancer Genome Atlas Research Network, 2012)
t(20;22)(q11;q12) PISD/RBL1 (Cancer Genome Atlas Research Network, 2012)
t(22;22)(q11;q11) THAP7/PRODH (Cancer Genome Atlas Research Network, 2012)
t(22;22)(q12;q12) APOL3/ISX (Cancer Genome Atlas Research Network, 2012)
t(22;22)(q12;q12) MCM5/TOM1 (Majewski et al., 2013)

6. Bibliography

KIF5B-RET fusions in Chinese patients with non-small cell lung cancer.
Cai W, Su C, Li X, Fan L, Zheng L, Fei K, Zhou C.
Cancer. 2013 Apr 15;119(8):1486-94.
PMID 23378251
 
Comprehensive genomic characterization of squamous cell lung cancers.
Cancer Genome Atlas Research Network.
Nature. 2012 Sep 27;489(7417):519-25.
PMID 22960745
 
Identifying and targeting ROS1 gene fusions in non-small cell lung cancer.
Davies KD, Le AT, Theodoro MF, Skokan MC, Aisner DL, Berge EM, Terracciano LM, Cappuzzo F, Incarbone M, Roncalli M, Alloisio M, Santoro A, Camidge DR, Varella-Garcia M, Doebele RC.
Clin Cancer Res. 2012 Sep 1;18(17):4570-9.
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Identification of recurrent FGFR3 fusion genes in lung cancer through kinome-centred RNA sequencing.
Majewski IJ, Mittempergher L, Davidson NM, Bosma A, Willems SM, Horlings HM, de Rink I, Greger L, Hooijer GK, Peters D, Nederlof PM, Hofland I, de Jong J, Wesseling J, Kluin RJ, Brugman W, Kerkhoven R, Nieboer F, Roepman P, Broeks A, Muley TR, Jassem J, Niklinski J, van Zandwijk N, Brazma A, Oshlack A, van den Heuvel M, Bernards R.
J Pathol. 2013 Jul;230(3):270-6.
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EML4-ALK rearrangement in non-small cell lung cancer and non-tumor lung tissues.
Martelli MP, Sozzi G, Hernandez L, Pettirossi V, Navarro A, Conte D, Gasparini P, Perrone F, Modena P, Pastorino U, Carbone A, Fabbri A, Sidoni A, Nakamura S, Gambacorta M, Fernandez PL, Ramirez J, Chan JK, Grigioni WF, Campo E, Pileri SA, Falini B.
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Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer.
Rikova K, Guo A, Zeng Q, Possemato A, Yu J, Haack H, Nardone J, Lee K, Reeves C, Li Y, Hu Y, Tan Z, Stokes M, Sullivan L, Mitchell J, Wetzel R, Macneill J, Ren JM, Yuan J, Bakalarski CE, Villen J, Kornhauser JM, Smith B, Li D, Zhou X, Gygi SP, Gu TL, Polakiewicz RD, Rush J, Comb MJ.
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FGFR1 amplification is associated with poor prognosis and smoking in non-small-cell lung cancer.
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Virchows Arch. 2014 Nov;465(5):547-58. doi: 10.1007/s00428-014-1634-2. Epub 2014 Aug 3.
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Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer.
Soda M, Choi YL, Enomoto M, Takada S, Yamashita Y, Ishikawa S, Fujiwara S, Watanabe H, Kurashina K, Hatanaka H, Bando M, Ohno S, Ishikawa Y, Aburatani H, Niki T, Sohara Y, Sugiyama Y, Mano H.
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Identification of targetable FGFR gene fusions in diverse cancers.
Wu YM, Su F, Kalyana-Sundaram S, Khazanov N, Ateeq B, Cao X, Lonigro RJ, Vats P, Wang R, Lin SF, Cheng AJ, Kunju LP, Siddiqui J, Tomlins SA, Wyngaard P, Sadis S, Roychowdhury S, Hussain MH, Feng FY, Zalupski MM, Talpaz M, Pienta KJ, Rhodes DR, Robinson DR, Chinnaiyan AM.
Cancer Discov. 2013 Jun;3(6):636-47.
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Analysis of clinical characteristics and differential diagnosis of the lung biopsy specimens in 99 adenocarcinoma cases and 111 squamous cell carcinoma cases: Utility of an immunohistochemical panel containing CK5/6, CK34bE12, p63, CK7 and TTF-1.
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7. Citation

This paper should be referenced as such :
Jean-Loup Huret
Lung: Translocations in Squamous Cell Carcinoma
Atlas Genet Cytogenet Oncol Haematol. 2015;19(8):545-549.
Free journal version : [ pdf ]   [ DOI ]
On line version : https://atlasgeneticsoncology.usal.es/classic/Tumors/TranslocLungSquamCellCarcID6819.html


8. Translocations implicated (Data extracted from papers in the Atlas)

 t(1;1)(p36;p36) PRKCZ/SKI
 t(1;1)(p34;q44) SMYD3/ELOVL1
 t(1;1)(q21;q21) GATAD2B/PRKAB2
 t(1;2)(p35;q37) ZBTB8B/TRAF3IP1
 t(1;2)(p12;p16) REL/MAN1A2
 t(1;2)(p12;p15) PHGDH/WDPCP
 t(1;3)(p34;q26) ATP11B/POU3F1
 t(1;3)(p34;q26) OSCP1/SOX2-OT
 t(1;3)(p33;q29) TFRC/NSUN4
 t(1;4)(p31;q22) BMPR1B/ALG6
 t(1;5)(p34;q31) CTNNA1/HEYL
 t(1;5)(q25;p13) DARS2/ZFR
 t(1;8)(p36;q21) SLC7A13/WDTC1
 t(1;8)(p32;q24) NRD1/KCNK9
 t(1;9)(p33;p13) KIF24/FAAH
 t(1;10)(p32;q21) CDK1/USP24
 t(1;10)(p31;p14) SFMBT2/PRKACB
 t(1;10)(q32;q22) TMEM206/PSAP
 t(1;11)(p31;q24) ETS1/NEGR1
 t(1;12)(q25;p12) HMCN1/ETNK1
 t(1;16)(q21;p12) CCP110/GOLPH3L
 t(1;17)(p21;q25) UNK/DPYD
 t(1;17)(p12;q11) ALDOC/MAN1A2
 t(1;21)(p35;q22) ITSN1/MATN1
 t(2;2)(p25;p25) ROCK2/SH3YL1
 t(2;2)(p24;p23) GPN1/KLHL29
 inv(2)(p21p23) EML4/ALK
 del(2)(p21p23) EML4/ALK
 t(2;2)(p21;p21) THADA/EML4
 t(2;2)(p16;p23) PSME4/PPP1CB
 t(2;2)(p15;p15) EHBP1/FAM161A
 t(2;2)(q21;q21) GPR39/MGAT5
 t(2;2)(q21;q24) ACVR1C/MGAT5
 t(2;2)(q23;q35) TNS1/RPRM
 t(2;3)(p16;q26) KCNMB2/NRXN1
 t(2;4)(p16;q13) BCL11A/EPHA5
 t(2;5)(p16;p15) NRXN1/PLEKHG4B
 t(2;5)(p11;p12) HCN1/FUNDC2P2
 t(2;5)(q35;p13) USP37/OSMR
 t(2;6)(p24;p22) ID4/FAM84A
 t(2;16)(q24;q11) ANKRD26P1/SLC4A10
 t(2;17)(p25;q21) CRHR1-IT1/ALLC
 t(2;18)(p24;q11) KLHL29/PSMA8
 t(2;22)(p12;q12) EVA1A/TTC28
 t(3;3)(p12;q29) PAK2/VGLL3
 t(3;3)(q11;q13) ALCAM/EPHA6
 t(3;3)(q12;q13) GSK3B/IMPG2
 t(3;3)(q13;q22) SLCO2A1/GUCA1C
 t(3;3)(q21;q22) RUVBL1/TMCC1
 t(3;3)(q22;q22) PIK3CB/BFSP2
 t(3;3)(q22;q22) TMCC1/C3orf36
 t(3;3)(q24;q26) HLTF/OTOL1
 t(3;3)(q25;q25) GMPS/C3orf55
 t(3;3)(q25;q26) IQCJ/BCHE
 t(3;3)(q25;q27) PPM1L/MCF2L2
 t(3;3)(q25;q28) PYDC2/C3orf79
 t(3;3)(q26;q26) ATP11B/SI
 t(3;3)(q26;q26) PHC3/FNDC3B
 t(3;3)(q26;q27) CCDC39/MCF2L2
 t(3;3)(q26;q28) SOX2/TPRG1
 t(3;3)(q27;q28) LPP/ST6GAL1
 t(3;3)(q27;q29) EHHADH/SENP5
 t(3;3)(q29;q29) LRCH3/MIR570
 t(3;4)(q26;p16) ATP11B/ZNF595
 t(3;8)(q27;q22) MCF2L2/MIR548A3
 t(3;8)(q29;p12) FYTTD1/WRN
 t(3;11)(q26;p15) PDE3B/ATP11B
 t(3;13)(q21;q33) TNFSF13B/MYLK
 t(3;17)(q25;p11) MAP2K3/SSR3
 t(3;17)(q29;q23) MIR21/WDR53
 t(3;19)(q27;q13) ACTN4/IGF2BP2
 t(3;20)(q21;q13) SLC12A8/BCAS1
 t(3;21)(p11;q21) POU1F1/TMPRSS15
 t(3;22)(q26;q11) ATP11B/TPTEP1
 del(4)(p16p16) FGFR3/TACC3
 t(4;4)(q13;q22) CCSER1/UGT2A1
 t(4;6)(p15;q22) SLC34A2/ROS1
 t(4;8)(q13;q24) COX18/ZFAT
 t(4;9)(q13;q32) ADAMTS3/SNX30
 t(4;10)(p13;q11) SGMS1/KCTD8
 t(5;5)(p15;p15) MARCH6/IRX4
 t(5;5)(p15;p15) ROPN1L/SEMA5A
 t(5;5)(p12;p13) RICTOR/FGF10
 t(5;6)(q33;q22) CD74/ROS1
 t(5;8)(p15;q21) MRPS28/ADAMTS16
 t(5;8)(p13;p11) EIF4EBP1/PRKAA1
 t(5;11)(q14;q22) FAM151B/CASP12
 t(5;11)(q35;q14) KCNIP1/KCTD14
 t(5;12)(p12;q13) NNT/AMIGO2
 t(6;6)(p25;p25) FAM50B/PPP1R3G
 t(6;6)(p22;q12) EYS/DEK
 t(6;6)(p21;p21) HLA-DOA/MUC21
 t(6;6)(p12;p22) BEND6/TRIM38
 t(6;6)(p12;q14) FAM83B/HTR1E
 t(6;6)(q14;q15) GABRR2/ME1
 t(6;13)(p21;q12) RPL7L1/CDK8
 t(6;14)(q24;q24) SASH1/DPF3
 t(6;16)(q13;p13) NTAN1/SLC17A5
 t(7;7)(p11;p12) VOPP1/GRB10
 t(7;7)(q22;q31) ANKRD7/DUS4L
 t(7;7)(q31;q33) CHCHD3/MET
 t(7;8)(p14;p23) AMPH/FDFT1
 t(7;10)(q36;q25) ACTR3C/SORCS1
 t(8;8)(p11;p11) ADAM9/RNF170
 t(8;8)(p11;p11) BAG4/FGFR1
 t(8;8)(p11;p11) LETM2/KCNU1
 t(8;8)(q11;q11) PRKDC/C8orf22
 t(8;8)(q23;q23) CSMD3/ANGPT1
 t(8;8)(q23;q23) OXR1/RSPO2
 t(8;9)(p12;p13) PURG/UBAP1
 t(8;9)(p11;p21) EIF4EBP1/C9orf53
 t(8;10)(p21;q26) FGFR2/KIAA1967
 t(8;10)(q23;q11) ANGPT1/CXCL12
 t(8;11)(q21;p15) HTATIP2/CA1
 t(8;15)(q21;q21) NEDD4/RDH10
 t(8;16)(p11;p12) KIAA0556/LSM1
 t(8;16)(q22;q24) GSE1/NACAP1
 t(8;21)(q11;q21) UBE2V2/NRIP1
 t(9;9)(p21;p21) CDKN2A/FOCAD
 t(9;9)(p21;p13) PLAA/RUSC2
 t(9;19)(p13;p13) FAM219A/S1PR5
 inv(10)(p11q11) KIF5B/RET
 t(10;11)(q21;p15) CTNNA3/IGF2
 t(10;11)(q22;q14) P4HA1/TRIM77P
 t(10;17)(q22;q12) SAMD8/LHX1
 t(10;20)(q23;q13) WAPAL/PTPRT
 t(11;11)(p14;p13) EIF3M/MPPED2
 t(11;11)(p11;q12) OR9Q1/OR4C46
 t(11;11)(q12;q12) P2RX3/RTN4RL2
 t(11;11)(q12;q13) EEF1G/PPP6R3
 t(11;11)(q12;q13) SHANK2/MS4A8B
 t(11;11)(q13;q22) PPP6R3/CNTN5
 t(11;12)(p11;p13) ERC1/SPI1
 t(12;20)(q12;q13) TAF4/ALG10B
 t(12;22)(q14;q12) SLC16A7/TTC28
 t(13;20)(q12;p12) MACROD2/MPHOSPH8
 t(14;14)(q11;q13) NPAS3/OXA1L
 t(14;14)(q12;q13) FOXG1/NPAS3
 t(14;14)(q13;q21) MBIP/C14orf183
 t(14;14)(q13;q21) SEC23A/IGBP1P1
 t(16;16)(q12;q13) FTO/HERPUD1
 t(16;16)(q23;q24) JPH3/OSGIN1
 t(16;22)(p12;q11) POM121L4P/LCMT1
 t(17;17)(p13;p11) PIGL/RABEP1
 t(17;17)(p11;q11) AKAP10/PSMD11
 t(17;17)(p11;q11) KIAA0100/ALKBH5
 t(17;17)(q23;q23) RPS6KB1/VMP1
 t(18;22)(q12;q11) CDC45/RIT2
 t(19;19)(p13;p12) UNC13A/ZNF492
 t(19;19)(q13;q13) BCL3/HIPK4
 t(19;19)(q13;q13) SIPA1L3/CD22
 t(19;21)(p13;q22) ITSN1/ZNF490
 t(19;22)(p12;q11) MMP11/ZNF714
 t(20;20)(q11;q13) ADNP/DLGAP4
 t(20;22)(q11;q12) PISD/RBL1
 t(22;22)(q11;q11) THAP7/PRODH
 t(22;22)(q12;q12) APOL3/ISX
 t(22;22)(q12;q12) MCM5/TOM1

9. External links

Mitelman database t(1;1)(p36;p36) [CaseList]     t(1;1)(p36;p36) [Transloc - MCList]   PRKCZ/SKI Fusion - MCList]
COSMIC[ PRKCZ ]   [ SKI ]
Mitelman database t(1;1)(p34;q44) [CaseList]     t(1;1)(p34;q44) [Transloc - MCList]   SMYD3/ELOVL1 Fusion - MCList]
COSMIC[ SMYD3 ]   [ ELOVL1 ]
Mitelman database t(1;1)(q21;q21) [CaseList]     t(1;1)(q21;q21) [Transloc - MCList]   GATAD2B/PRKAB2 Fusion - MCList]
COSMIC[ GATAD2B ]   [ PRKAB2 ]
Mitelman database t(1;2)(p35;q37) [CaseList]     t(1;2)(p35;q37) [Transloc - MCList]   ZBTB8B/TRAF3IP1 Fusion - MCList]
COSMIC[ ZBTB8B ]   [ TRAF3IP1 ]
Mitelman database t(1;2)(p12;p16) [CaseList]     t(1;2)(p12;p16) [Transloc - MCList]   REL/MAN1A2 Fusion - MCList]
COSMIC[ REL ]   [ MAN1A2 ]
Mitelman database t(1;2)(p12;p15) [CaseList]     t(1;2)(p12;p15) [Transloc - MCList]   PHGDH/WDPCP Fusion - MCList]
COSMIC[ PHGDH ]   [ WDPCP ]
Mitelman database t(1;3)(p34;q26) [CaseList]     t(1;3)(p34;q26) [Transloc - MCList]   ATP11B/POU3F1 Fusion - MCList]
COSMIC[ ATP11B ]   [ POU3F1 ]
Mitelman database t(1;3)(p34;q26) [CaseList]     t(1;3)(p34;q26) [Transloc - MCList]   OSCP1/SOX2-OT Fusion - MCList]
COSMIC[ OSCP1 ]   [ SOX2-OT ]
Mitelman database t(1;3)(p33;q29) [CaseList]     t(1;3)(p33;q29) [Transloc - MCList]   TFRC/NSUN4 Fusion - MCList]
COSMIC[ TFRC ]   [ NSUN4 ]
Mitelman database t(1;4)(p31;q22) [CaseList]     t(1;4)(p31;q22) [Transloc - MCList]   BMPR1B/ALG6 Fusion - MCList]
COSMIC[ BMPR1B ]   [ ALG6 ]
Mitelman database t(1;5)(p34;q31) [CaseList]     t(1;5)(p34;q31) [Transloc - MCList]   CTNNA1/HEYL Fusion - MCList]
COSMIC[ CTNNA1 ]   [ HEYL ]
Mitelman database t(1;5)(q25;p13) [CaseList]     t(1;5)(q25;p13) [Transloc - MCList]   DARS2/ZFR Fusion - MCList]
COSMIC[ DARS2 ]   [ ZFR ]
Mitelman database t(1;8)(p36;q21) [CaseList]     t(1;8)(p36;q21) [Transloc - MCList]   SLC7A13/WDTC1 Fusion - MCList]
COSMIC[ SLC7A13 ]   [ WDTC1 ]
Mitelman database t(1;8)(p32;q24) [CaseList]     t(1;8)(p32;q24) [Transloc - MCList]   NRD1/KCNK9 Fusion - MCList]
COSMIC[ NRD1 ]   [ KCNK9 ]
Mitelman database t(1;9)(p33;p13) [CaseList]     t(1;9)(p33;p13) [Transloc - MCList]   KIF24/FAAH Fusion - MCList]
COSMIC[ KIF24 ]   [ FAAH ]
Mitelman database t(1;10)(p32;q21) [CaseList]     t(1;10)(p32;q21) [Transloc - MCList]   CDK1/USP24 Fusion - MCList]
COSMIC[ CDK1 ]   [ USP24 ]
Mitelman database t(1;10)(p31;p14) [CaseList]     t(1;10)(p31;p14) [Transloc - MCList]   SFMBT2/PRKACB Fusion - MCList]
COSMIC[ SFMBT2 ]   [ PRKACB ]
Mitelman database t(1;10)(q32;q22) [CaseList]     t(1;10)(q32;q22) [Transloc - MCList]   TMEM206/PSAP Fusion - MCList]
COSMIC[ TMEM206 ]   [ PSAP ]
Mitelman database t(1;11)(p31;q24) [CaseList]     t(1;11)(p31;q24) [Transloc - MCList]   ETS1/NEGR1 Fusion - MCList]
COSMIC[ ETS1 ]   [ NEGR1 ]
Mitelman database t(1;12)(q25;p12) [CaseList]     t(1;12)(q25;p12) [Transloc - MCList]   HMCN1/ETNK1 Fusion - MCList]
COSMIC[ HMCN1 ]   [ ETNK1 ]
Mitelman database t(1;16)(q21;p12) [CaseList]     t(1;16)(q21;p12) [Transloc - MCList]   CCP110/GOLPH3L Fusion - MCList]
COSMIC[ CCP110 ]   [ GOLPH3L ]
Mitelman database t(1;17)(p21;q25) [CaseList]     t(1;17)(p21;q25) [Transloc - MCList]   UNK/DPYD Fusion - MCList]
COSMIC[ UNK ]   [ DPYD ]
Mitelman database t(1;17)(p12;q11) [CaseList]     t(1;17)(p12;q11) [Transloc - MCList]   ALDOC/MAN1A2 Fusion - MCList]
COSMIC[ ALDOC ]   [ MAN1A2 ]
Mitelman database t(1;21)(p35;q22) [CaseList]     t(1;21)(p35;q22) [Transloc - MCList]   ITSN1/MATN1 Fusion - MCList]
COSMIC[ ITSN1 ]   [ MATN1 ]
Mitelman database t(2;2)(p25;p25) [CaseList]     t(2;2)(p25;p25) [Transloc - MCList]   ROCK2/SH3YL1 Fusion - MCList]
COSMIC[ ROCK2 ]   [ SH3YL1 ]
Mitelman database t(2;2)(p24;p23) [CaseList]     t(2;2)(p24;p23) [Transloc - MCList]   GPN1/KLHL29 Fusion - MCList]
COSMIC[ GPN1 ]   [ KLHL29 ]
Mitelman database inv(2)(p21p23) [CaseList]     inv(2)(p21p23) [Transloc - MCList]   EML4/ALK Fusion - MCList]
COSMIC[ EML4 ]   [ ALK ]
Mitelman database del(2)(p21p23) [CaseList]     del(2)(p21p23) [Transloc - MCList]   EML4/ALK Fusion - MCList]
COSMIC[ EML4 ]   [ ALK ]
Mitelman database t(2;2)(p21;p21) [CaseList]     t(2;2)(p21;p21) [Transloc - MCList]   THADA/EML4 Fusion - MCList]
COSMIC[ THADA ]   [ EML4 ]
Mitelman database t(2;2)(p16;p23) [CaseList]     t(2;2)(p16;p23) [Transloc - MCList]   PSME4/PPP1CB Fusion - MCList]
COSMIC[ PSME4 ]   [ PPP1CB ]
Mitelman database t(2;2)(p15;p15) [CaseList]     t(2;2)(p15;p15) [Transloc - MCList]   EHBP1/FAM161A Fusion - MCList]
COSMIC[ EHBP1 ]   [ FAM161A ]
Mitelman database t(2;2)(q21;q21) [CaseList]     t(2;2)(q21;q21) [Transloc - MCList]   GPR39/MGAT5 Fusion - MCList]
COSMIC[ GPR39 ]   [ MGAT5 ]
Mitelman database t(2;2)(q21;q24) [CaseList]     t(2;2)(q21;q24) [Transloc - MCList]   ACVR1C/MGAT5 Fusion - MCList]
COSMIC[ ACVR1C ]   [ MGAT5 ]
Mitelman database t(2;2)(q23;q35) [CaseList]     t(2;2)(q23;q35) [Transloc - MCList]   TNS1/RPRM Fusion - MCList]
COSMIC[ TNS1 ]   [ RPRM ]
Mitelman database t(2;3)(p16;q26) [CaseList]     t(2;3)(p16;q26) [Transloc - MCList]   KCNMB2/NRXN1 Fusion - MCList]
COSMIC[ KCNMB2 ]   [ NRXN1 ]
Mitelman database t(2;4)(p16;q13) [CaseList]     t(2;4)(p16;q13) [Transloc - MCList]   BCL11A/EPHA5 Fusion - MCList]
COSMIC[ BCL11A ]   [ EPHA5 ]
Mitelman database t(2;5)(p16;p15) [CaseList]     t(2;5)(p16;p15) [Transloc - MCList]   NRXN1/PLEKHG4B Fusion - MCList]
COSMIC[ NRXN1 ]   [ PLEKHG4B ]
Mitelman database t(2;5)(p11;p12) [CaseList]     t(2;5)(p11;p12) [Transloc - MCList]   HCN1/FUNDC2P2 Fusion - MCList]
COSMIC[ HCN1 ]   [ FUNDC2P2 ]
Mitelman database t(2;5)(q35;p13) [CaseList]     t(2;5)(q35;p13) [Transloc - MCList]   USP37/OSMR Fusion - MCList]
COSMIC[ USP37 ]   [ OSMR ]
Mitelman database t(2;6)(p24;p22) [CaseList]     t(2;6)(p24;p22) [Transloc - MCList]   ID4/FAM84A Fusion - MCList]
COSMIC[ ID4 ]   [ FAM84A ]
Mitelman database t(2;16)(q24;q11) [CaseList]     t(2;16)(q24;q11) [Transloc - MCList]   ANKRD26P1/SLC4A10 Fusion - MCList]
COSMIC[ ANKRD26P1 ]   [ SLC4A10 ]
Mitelman database t(2;17)(p25;q21) [CaseList]     t(2;17)(p25;q21) [Transloc - MCList]   CRHR1-IT1/ALLC Fusion - MCList]
COSMIC[ CRHR1-IT1 ]   [ ALLC ]
Mitelman database t(2;18)(p24;q11) [CaseList]     t(2;18)(p24;q11) [Transloc - MCList]   KLHL29/PSMA8 Fusion - MCList]
COSMIC[ KLHL29 ]   [ PSMA8 ]
Mitelman database t(2;22)(p12;q12) [CaseList]     t(2;22)(p12;q12) [Transloc - MCList]   EVA1A/TTC28 Fusion - MCList]
COSMIC[ EVA1A ]   [ TTC28 ]
Mitelman database t(3;3)(p12;q29) [CaseList]     t(3;3)(p12;q29) [Transloc - MCList]   PAK2/VGLL3 Fusion - MCList]
COSMIC[ PAK2 ]   [ VGLL3 ]
Mitelman database t(3;3)(q11;q13) [CaseList]     t(3;3)(q11;q13) [Transloc - MCList]   ALCAM/EPHA6 Fusion - MCList]
COSMIC[ ALCAM ]   [ EPHA6 ]
Mitelman database t(3;3)(q12;q13) [CaseList]     t(3;3)(q12;q13) [Transloc - MCList]   GSK3B/IMPG2 Fusion - MCList]
COSMIC[ GSK3B ]   [ IMPG2 ]
Mitelman database t(3;3)(q13;q22) [CaseList]     t(3;3)(q13;q22) [Transloc - MCList]   SLCO2A1/GUCA1C Fusion - MCList]
COSMIC[ SLCO2A1 ]   [ GUCA1C ]
Mitelman database t(3;3)(q21;q22) [CaseList]     t(3;3)(q21;q22) [Transloc - MCList]   RUVBL1/TMCC1 Fusion - MCList]
COSMIC[ RUVBL1 ]   [ TMCC1 ]
Mitelman database t(3;3)(q22;q22) [CaseList]     t(3;3)(q22;q22) [Transloc - MCList]   PIK3CB/BFSP2 Fusion - MCList]
COSMIC[ PIK3CB ]   [ BFSP2 ]
Mitelman database t(3;3)(q22;q22) [CaseList]     t(3;3)(q22;q22) [Transloc - MCList]   TMCC1/C3orf36 Fusion - MCList]
COSMIC[ TMCC1 ]   [ C3orf36 ]
Mitelman database t(3;3)(q24;q26) [CaseList]     t(3;3)(q24;q26) [Transloc - MCList]   HLTF/OTOL1 Fusion - MCList]
COSMIC[ HLTF ]   [ OTOL1 ]
Mitelman database t(3;3)(q25;q25) [CaseList]     t(3;3)(q25;q25) [Transloc - MCList]   GMPS/C3orf55 Fusion - MCList]
COSMIC[ GMPS ]   [ C3orf55 ]
Mitelman database t(3;3)(q25;q26) [CaseList]     t(3;3)(q25;q26) [Transloc - MCList]   IQCJ/BCHE Fusion - MCList]
COSMIC[ IQCJ ]   [ BCHE ]
Mitelman database t(3;3)(q25;q27) [CaseList]     t(3;3)(q25;q27) [Transloc - MCList]   PPM1L/MCF2L2 Fusion - MCList]
COSMIC[ PPM1L ]   [ MCF2L2 ]
Mitelman database t(3;3)(q25;q28) [CaseList]     t(3;3)(q25;q28) [Transloc - MCList]   PYDC2/C3orf79 Fusion - MCList]
COSMIC[ PYDC2 ]   [ C3orf79 ]
Mitelman database t(3;3)(q26;q26) [CaseList]     t(3;3)(q26;q26) [Transloc - MCList]   ATP11B/SI Fusion - MCList]
COSMIC[ ATP11B ]   [ SI ]
Mitelman database t(3;3)(q26;q26) [CaseList]     t(3;3)(q26;q26) [Transloc - MCList]   PHC3/FNDC3B Fusion - MCList]
COSMIC[ PHC3 ]   [ FNDC3B ]
Mitelman database t(3;3)(q26;q27) [CaseList]     t(3;3)(q26;q27) [Transloc - MCList]   CCDC39/MCF2L2 Fusion - MCList]
COSMIC[ CCDC39 ]   [ MCF2L2 ]
Mitelman database t(3;3)(q26;q28) [CaseList]     t(3;3)(q26;q28) [Transloc - MCList]   SOX2/TPRG1 Fusion - MCList]
COSMIC[ SOX2 ]   [ TPRG1 ]
Mitelman database t(3;3)(q27;q28) [CaseList]     t(3;3)(q27;q28) [Transloc - MCList]   LPP/ST6GAL1 Fusion - MCList]
COSMIC[ LPP ]   [ ST6GAL1 ]
Mitelman database t(3;3)(q27;q29) [CaseList]     t(3;3)(q27;q29) [Transloc - MCList]   EHHADH/SENP5 Fusion - MCList]
COSMIC[ EHHADH ]   [ SENP5 ]
Mitelman database t(3;3)(q29;q29) [CaseList]     t(3;3)(q29;q29) [Transloc - MCList]   LRCH3/MIR570 Fusion - MCList]
COSMIC[ LRCH3 ]   [ MIR570 ]
Mitelman database t(3;4)(q26;p16) [CaseList]     t(3;4)(q26;p16) [Transloc - MCList]   ATP11B/ZNF595 Fusion - MCList]
COSMIC[ ATP11B ]   [ ZNF595 ]
Mitelman database t(3;8)(q27;q22) [CaseList]     t(3;8)(q27;q22) [Transloc - MCList]   MCF2L2/MIR548A3 Fusion - MCList]
COSMIC[ MCF2L2 ]   [ MIR548A3 ]
Mitelman database t(3;8)(q29;p12) [CaseList]     t(3;8)(q29;p12) [Transloc - MCList]   FYTTD1/WRN Fusion - MCList]
COSMIC[ FYTTD1 ]   [ WRN ]
Mitelman database t(3;11)(q26;p15) [CaseList]     t(3;11)(q26;p15) [Transloc - MCList]   PDE3B/ATP11B Fusion - MCList]
COSMIC[ PDE3B ]   [ ATP11B ]
Mitelman database t(3;13)(q21;q33) [CaseList]     t(3;13)(q21;q33) [Transloc - MCList]   TNFSF13B/MYLK Fusion - MCList]
COSMIC[ TNFSF13B ]   [ MYLK ]
Mitelman database t(3;17)(q25;p11) [CaseList]     t(3;17)(q25;p11) [Transloc - MCList]   MAP2K3/SSR3 Fusion - MCList]
COSMIC[ MAP2K3 ]   [ SSR3 ]
Mitelman database t(3;17)(q29;q23) [CaseList]     t(3;17)(q29;q23) [Transloc - MCList]   MIR21/WDR53 Fusion - MCList]
COSMIC[ MIR21 ]   [ WDR53 ]
Mitelman database t(3;19)(q27;q13) [CaseList]     t(3;19)(q27;q13) [Transloc - MCList]   ACTN4/IGF2BP2 Fusion - MCList]
COSMIC[ ACTN4 ]   [ IGF2BP2 ]
Mitelman database t(3;20)(q21;q13) [CaseList]     t(3;20)(q21;q13) [Transloc - MCList]   SLC12A8/BCAS1 Fusion - MCList]
COSMIC[ SLC12A8 ]   [ BCAS1 ]
Mitelman database t(3;21)(p11;q21) [CaseList]     t(3;21)(p11;q21) [Transloc - MCList]   POU1F1/TMPRSS15 Fusion - MCList]
COSMIC[ POU1F1 ]   [ TMPRSS15 ]
Mitelman database t(3;22)(q26;q11) [CaseList]     t(3;22)(q26;q11) [Transloc - MCList]   ATP11B/TPTEP1 Fusion - MCList]
COSMIC[ ATP11B ]   [ TPTEP1 ]
Mitelman database del(4)(p16p16) [CaseList]     del(4)(p16p16) [Transloc - MCList]   FGFR3/TACC3 Fusion - MCList]
COSMIC[ FGFR3 ]   [ TACC3 ]
Mitelman database t(4;4)(q13;q22) [CaseList]     t(4;4)(q13;q22) [Transloc - MCList]   CCSER1/UGT2A1 Fusion - MCList]
COSMIC[ CCSER1 ]   [ UGT2A1 ]
Mitelman database t(4;6)(p15;q22) [CaseList]     t(4;6)(p15;q22) [Transloc - MCList]   SLC34A2/ROS1 Fusion - MCList]
COSMIC[ SLC34A2 ]   [ ROS1 ]
Mitelman database t(4;8)(q13;q24) [CaseList]     t(4;8)(q13;q24) [Transloc - MCList]   COX18/ZFAT Fusion - MCList]
COSMIC[ COX18 ]   [ ZFAT ]
Mitelman database t(4;9)(q13;q32) [CaseList]     t(4;9)(q13;q32) [Transloc - MCList]   ADAMTS3/SNX30 Fusion - MCList]
COSMIC[ ADAMTS3 ]   [ SNX30 ]
Mitelman database t(4;10)(p13;q11) [CaseList]     t(4;10)(p13;q11) [Transloc - MCList]   SGMS1/KCTD8 Fusion - MCList]
COSMIC[ SGMS1 ]   [ KCTD8 ]
Mitelman database t(5;5)(p15;p15) [CaseList]     t(5;5)(p15;p15) [Transloc - MCList]   MARCH6/IRX4 Fusion - MCList]
COSMIC[ MARCH6 ]   [ IRX4 ]
Mitelman database t(5;5)(p15;p15) [CaseList]     t(5;5)(p15;p15) [Transloc - MCList]   ROPN1L/SEMA5A Fusion - MCList]
COSMIC[ ROPN1L ]   [ SEMA5A ]
Mitelman database t(5;5)(p12;p13) [CaseList]     t(5;5)(p12;p13) [Transloc - MCList]   RICTOR/FGF10 Fusion - MCList]
COSMIC[ RICTOR ]   [ FGF10 ]
Mitelman database t(5;6)(q33;q22) [CaseList]     t(5;6)(q33;q22) [Transloc - MCList]   CD74/ROS1 Fusion - MCList]
COSMIC[ CD74 ]   [ ROS1 ]
Mitelman database t(5;8)(p15;q21) [CaseList]     t(5;8)(p15;q21) [Transloc - MCList]   MRPS28/ADAMTS16 Fusion - MCList]
COSMIC[ MRPS28 ]   [ ADAMTS16 ]
Mitelman database t(5;8)(p13;p11) [CaseList]     t(5;8)(p13;p11) [Transloc - MCList]   EIF4EBP1/PRKAA1 Fusion - MCList]
COSMIC[ EIF4EBP1 ]   [ PRKAA1 ]
Mitelman database t(5;11)(q14;q22) [CaseList]     t(5;11)(q14;q22) [Transloc - MCList]   FAM151B/CASP12 Fusion - MCList]
COSMIC[ FAM151B ]   [ CASP12 ]
Mitelman database t(5;11)(q35;q14) [CaseList]     t(5;11)(q35;q14) [Transloc - MCList]   KCNIP1/KCTD14 Fusion - MCList]
COSMIC[ KCNIP1 ]   [ KCTD14 ]
Mitelman database t(5;12)(p12;q13) [CaseList]     t(5;12)(p12;q13) [Transloc - MCList]   NNT/AMIGO2 Fusion - MCList]
COSMIC[ NNT ]   [ AMIGO2 ]
Mitelman database t(6;6)(p25;p25) [CaseList]     t(6;6)(p25;p25) [Transloc - MCList]   FAM50B/PPP1R3G Fusion - MCList]
COSMIC[ FAM50B ]   [ PPP1R3G ]
Mitelman database t(6;6)(p22;q12) [CaseList]     t(6;6)(p22;q12) [Transloc - MCList]   EYS/DEK Fusion - MCList]
COSMIC[ EYS ]   [ DEK ]
Mitelman database t(6;6)(p21;p21) [CaseList]     t(6;6)(p21;p21) [Transloc - MCList]   HLA-DOA/MUC21 Fusion - MCList]
COSMIC[ HLA-DOA ]   [ MUC21 ]
Mitelman database t(6;6)(p12;p22) [CaseList]     t(6;6)(p12;p22) [Transloc - MCList]   BEND6/TRIM38 Fusion - MCList]
COSMIC[ BEND6 ]   [ TRIM38 ]
Mitelman database t(6;6)(p12;q14) [CaseList]     t(6;6)(p12;q14) [Transloc - MCList]   FAM83B/HTR1E Fusion - MCList]
COSMIC[ FAM83B ]   [ HTR1E ]
Mitelman database t(6;6)(q14;q15) [CaseList]     t(6;6)(q14;q15) [Transloc - MCList]   GABRR2/ME1 Fusion - MCList]
COSMIC[ GABRR2 ]   [ ME1 ]
Mitelman database t(6;13)(p21;q12) [CaseList]     t(6;13)(p21;q12) [Transloc - MCList]   RPL7L1/CDK8 Fusion - MCList]
COSMIC[ RPL7L1 ]   [ CDK8 ]
Mitelman database t(6;14)(q24;q24) [CaseList]     t(6;14)(q24;q24) [Transloc - MCList]   SASH1/DPF3 Fusion - MCList]
COSMIC[ SASH1 ]   [ DPF3 ]
Mitelman database t(6;16)(q13;p13) [CaseList]     t(6;16)(q13;p13) [Transloc - MCList]   NTAN1/SLC17A5 Fusion - MCList]
COSMIC[ NTAN1 ]   [ SLC17A5 ]
Mitelman database t(7;7)(p11;p12) [CaseList]     t(7;7)(p11;p12) [Transloc - MCList]   VOPP1/GRB10 Fusion - MCList]
COSMIC[ VOPP1 ]   [ GRB10 ]
Mitelman database t(7;7)(q22;q31) [CaseList]     t(7;7)(q22;q31) [Transloc - MCList]   ANKRD7/DUS4L Fusion - MCList]
COSMIC[ ANKRD7 ]   [ DUS4L ]
Mitelman database t(7;7)(q31;q33) [CaseList]     t(7;7)(q31;q33) [Transloc - MCList]   CHCHD3/MET Fusion - MCList]
COSMIC[ CHCHD3 ]   [ MET ]
Mitelman database t(7;8)(p14;p23) [CaseList]     t(7;8)(p14;p23) [Transloc - MCList]   AMPH/FDFT1 Fusion - MCList]
COSMIC[ AMPH ]   [ FDFT1 ]
Mitelman database t(7;10)(q36;q25) [CaseList]     t(7;10)(q36;q25) [Transloc - MCList]   ACTR3C/SORCS1 Fusion - MCList]
COSMIC[ ACTR3C ]   [ SORCS1 ]
Mitelman database t(8;8)(p11;p11) [CaseList]     t(8;8)(p11;p11) [Transloc - MCList]   ADAM9/RNF170 Fusion - MCList]
COSMIC[ ADAM9 ]   [ RNF170 ]
Mitelman database t(8;8)(p11;p11) [CaseList]     t(8;8)(p11;p11) [Transloc - MCList]   BAG4/FGFR1 Fusion - MCList]
COSMIC[ BAG4 ]   [ FGFR1 ]
Mitelman database t(8;8)(p11;p11) [CaseList]     t(8;8)(p11;p11) [Transloc - MCList]   LETM2/KCNU1 Fusion - MCList]
COSMIC[ LETM2 ]   [ KCNU1 ]
Mitelman database t(8;8)(q11;q11) [CaseList]     t(8;8)(q11;q11) [Transloc - MCList]   PRKDC/C8orf22 Fusion - MCList]
COSMIC[ PRKDC ]   [ C8orf22 ]
Mitelman database t(8;8)(q23;q23) [CaseList]     t(8;8)(q23;q23) [Transloc - MCList]   CSMD3/ANGPT1 Fusion - MCList]
COSMIC[ CSMD3 ]   [ ANGPT1 ]
Mitelman database t(8;8)(q23;q23) [CaseList]     t(8;8)(q23;q23) [Transloc - MCList]   OXR1/RSPO2 Fusion - MCList]
COSMIC[ OXR1 ]   [ RSPO2 ]
Mitelman database t(8;9)(p12;p13) [CaseList]     t(8;9)(p12;p13) [Transloc - MCList]   PURG/UBAP1 Fusion - MCList]
COSMIC[ PURG ]   [ UBAP1 ]
Mitelman database t(8;9)(p11;p21) [CaseList]     t(8;9)(p11;p21) [Transloc - MCList]   EIF4EBP1/C9orf53 Fusion - MCList]
COSMIC[ EIF4EBP1 ]   [ C9orf53 ]
Mitelman database t(8;10)(p21;q26) [CaseList]     t(8;10)(p21;q26) [Transloc - MCList]   FGFR2/KIAA1967 Fusion - MCList]
COSMIC[ FGFR2 ]   [ KIAA1967 ]
Mitelman database t(8;10)(q23;q11) [CaseList]     t(8;10)(q23;q11) [Transloc - MCList]   ANGPT1/CXCL12 Fusion - MCList]
COSMIC[ ANGPT1 ]   [ CXCL12 ]
Mitelman database t(8;11)(q21;p15) [CaseList]     t(8;11)(q21;p15) [Transloc - MCList]   HTATIP2/CA1 Fusion - MCList]
COSMIC[ HTATIP2 ]   [ CA1 ]
Mitelman database t(8;15)(q21;q21) [CaseList]     t(8;15)(q21;q21) [Transloc - MCList]   NEDD4/RDH10 Fusion - MCList]
COSMIC[ NEDD4 ]   [ RDH10 ]
Mitelman database t(8;16)(p11;p12) [CaseList]     t(8;16)(p11;p12) [Transloc - MCList]   KIAA0556/LSM1 Fusion - MCList]
COSMIC[ KIAA0556 ]   [ LSM1 ]
Mitelman database t(8;16)(q22;q24) [CaseList]     t(8;16)(q22;q24) [Transloc - MCList]   GSE1/NACAP1 Fusion - MCList]
COSMIC[ GSE1 ]   [ NACAP1 ]
Mitelman database t(8;21)(q11;q21) [CaseList]     t(8;21)(q11;q21) [Transloc - MCList]   UBE2V2/NRIP1 Fusion - MCList]
COSMIC[ UBE2V2 ]   [ NRIP1 ]
Mitelman database t(9;9)(p21;p21) [CaseList]     t(9;9)(p21;p21) [Transloc - MCList]   CDKN2A/FOCAD Fusion - MCList]
COSMIC[ CDKN2A ]   [ FOCAD ]
Mitelman database t(9;9)(p21;p13) [CaseList]     t(9;9)(p21;p13) [Transloc - MCList]   PLAA/RUSC2 Fusion - MCList]
COSMIC[ PLAA ]   [ RUSC2 ]
Mitelman database t(9;19)(p13;p13) [CaseList]     t(9;19)(p13;p13) [Transloc - MCList]   FAM219A/S1PR5 Fusion - MCList]
COSMIC[ FAM219A ]   [ S1PR5 ]
Mitelman database inv(10)(p11q11) [CaseList]     inv(10)(p11q11) [Transloc - MCList]   KIF5B/RET Fusion - MCList]
COSMIC[ KIF5B ]   [ RET ]
Mitelman database t(10;11)(q21;p15) [CaseList]     t(10;11)(q21;p15) [Transloc - MCList]   CTNNA3/IGF2 Fusion - MCList]
COSMIC[ CTNNA3 ]   [ IGF2 ]
Mitelman database t(10;11)(q22;q14) [CaseList]     t(10;11)(q22;q14) [Transloc - MCList]   P4HA1/TRIM77P Fusion - MCList]
COSMIC[ P4HA1 ]   [ TRIM77P ]
Mitelman database t(10;17)(q22;q12) [CaseList]     t(10;17)(q22;q12) [Transloc - MCList]   SAMD8/LHX1 Fusion - MCList]
COSMIC[ SAMD8 ]   [ LHX1 ]
Mitelman database t(10;20)(q23;q13) [CaseList]     t(10;20)(q23;q13) [Transloc - MCList]   WAPAL/PTPRT Fusion - MCList]
COSMIC[ WAPAL ]   [ PTPRT ]
Mitelman database t(11;11)(p14;p13) [CaseList]     t(11;11)(p14;p13) [Transloc - MCList]   EIF3M/MPPED2 Fusion - MCList]
COSMIC[ EIF3M ]   [ MPPED2 ]
Mitelman database t(11;11)(p11;q12) [CaseList]     t(11;11)(p11;q12) [Transloc - MCList]   OR9Q1/OR4C46 Fusion - MCList]
COSMIC[ OR9Q1 ]   [ OR4C46 ]
Mitelman database t(11;11)(q12;q12) [CaseList]     t(11;11)(q12;q12) [Transloc - MCList]   P2RX3/RTN4RL2 Fusion - MCList]
COSMIC[ P2RX3 ]   [ RTN4RL2 ]
Mitelman database t(11;11)(q12;q13) [CaseList]     t(11;11)(q12;q13) [Transloc - MCList]   EEF1G/PPP6R3 Fusion - MCList]
COSMIC[ EEF1G ]   [ PPP6R3 ]
Mitelman database t(11;11)(q12;q13) [CaseList]     t(11;11)(q12;q13) [Transloc - MCList]   SHANK2/MS4A8B Fusion - MCList]
COSMIC[ SHANK2 ]   [ MS4A8B ]
Mitelman database t(11;11)(q13;q22) [CaseList]     t(11;11)(q13;q22) [Transloc - MCList]   PPP6R3/CNTN5 Fusion - MCList]
COSMIC[ PPP6R3 ]   [ CNTN5 ]
Mitelman database t(11;12)(p11;p13) [CaseList]     t(11;12)(p11;p13) [Transloc - MCList]   ERC1/SPI1 Fusion - MCList]
COSMIC[ ERC1 ]   [ SPI1 ]
Mitelman database t(12;20)(q12;q13) [CaseList]     t(12;20)(q12;q13) [Transloc - MCList]   TAF4/ALG10B Fusion - MCList]
COSMIC[ TAF4 ]   [ ALG10B ]
Mitelman database t(12;22)(q14;q12) [CaseList]     t(12;22)(q14;q12) [Transloc - MCList]   SLC16A7/TTC28 Fusion - MCList]
COSMIC[ SLC16A7 ]   [ TTC28 ]
Mitelman database t(13;20)(q12;p12) [CaseList]     t(13;20)(q12;p12) [Transloc - MCList]   MACROD2/MPHOSPH8 Fusion - MCList]
COSMIC[ MACROD2 ]   [ MPHOSPH8 ]
Mitelman database t(14;14)(q11;q13) [CaseList]     t(14;14)(q11;q13) [Transloc - MCList]   NPAS3/OXA1L Fusion - MCList]
COSMIC[ NPAS3 ]   [ OXA1L ]
Mitelman database t(14;14)(q12;q13) [CaseList]     t(14;14)(q12;q13) [Transloc - MCList]   FOXG1/NPAS3 Fusion - MCList]
COSMIC[ FOXG1 ]   [ NPAS3 ]
Mitelman database t(14;14)(q13;q21) [CaseList]     t(14;14)(q13;q21) [Transloc - MCList]   MBIP/C14orf183 Fusion - MCList]
COSMIC[ MBIP ]   [ C14orf183 ]
Mitelman database t(14;14)(q13;q21) [CaseList]     t(14;14)(q13;q21) [Transloc - MCList]   SEC23A/IGBP1P1 Fusion - MCList]
COSMIC[ SEC23A ]   [ IGBP1P1 ]
Mitelman database t(16;16)(q12;q13) [CaseList]     t(16;16)(q12;q13) [Transloc - MCList]   FTO/HERPUD1 Fusion - MCList]
COSMIC[ FTO ]   [ HERPUD1 ]
Mitelman database t(16;16)(q23;q24) [CaseList]     t(16;16)(q23;q24) [Transloc - MCList]   JPH3/OSGIN1 Fusion - MCList]
COSMIC[ JPH3 ]   [ OSGIN1 ]
Mitelman database t(16;22)(p12;q11) [CaseList]     t(16;22)(p12;q11) [Transloc - MCList]   POM121L4P/LCMT1 Fusion - MCList]
COSMIC[ POM121L4P ]   [ LCMT1 ]
Mitelman database t(17;17)(p13;p11) [CaseList]     t(17;17)(p13;p11) [Transloc - MCList]   PIGL/RABEP1 Fusion - MCList]
COSMIC[ PIGL ]   [ RABEP1 ]
Mitelman database t(17;17)(p11;q11) [CaseList]     t(17;17)(p11;q11) [Transloc - MCList]   AKAP10/PSMD11 Fusion - MCList]
COSMIC[ AKAP10 ]   [ PSMD11 ]
Mitelman database t(17;17)(p11;q11) [CaseList]     t(17;17)(p11;q11) [Transloc - MCList]   KIAA0100/ALKBH5 Fusion - MCList]
COSMIC[ KIAA0100 ]   [ ALKBH5 ]
Mitelman database t(17;17)(q23;q23) [CaseList]     t(17;17)(q23;q23) [Transloc - MCList]   RPS6KB1/VMP1 Fusion - MCList]
COSMIC[ RPS6KB1 ]   [ VMP1 ]
Mitelman database t(18;22)(q12;q11) [CaseList]     t(18;22)(q12;q11) [Transloc - MCList]   CDC45/RIT2 Fusion - MCList]
COSMIC[ CDC45 ]   [ RIT2 ]
Mitelman database t(19;19)(p13;p12) [CaseList]     t(19;19)(p13;p12) [Transloc - MCList]   UNC13A/ZNF492 Fusion - MCList]
COSMIC[ UNC13A ]   [ ZNF492 ]
Mitelman database t(19;19)(q13;q13) [CaseList]     t(19;19)(q13;q13) [Transloc - MCList]   BCL3/HIPK4 Fusion - MCList]
COSMIC[ BCL3 ]   [ HIPK4 ]
Mitelman database t(19;19)(q13;q13) [CaseList]     t(19;19)(q13;q13) [Transloc - MCList]   SIPA1L3/CD22 Fusion - MCList]
COSMIC[ SIPA1L3 ]   [ CD22 ]
Mitelman database t(19;21)(p13;q22) [CaseList]     t(19;21)(p13;q22) [Transloc - MCList]   ITSN1/ZNF490 Fusion - MCList]
COSMIC[ ITSN1 ]   [ ZNF490 ]
Mitelman database t(19;22)(p12;q11) [CaseList]     t(19;22)(p12;q11) [Transloc - MCList]   MMP11/ZNF714 Fusion - MCList]
COSMIC[ MMP11 ]   [ ZNF714 ]
Mitelman database t(20;20)(q11;q13) [CaseList]     t(20;20)(q11;q13) [Transloc - MCList]   ADNP/DLGAP4 Fusion - MCList]
COSMIC[ ADNP ]   [ DLGAP4 ]
Mitelman database t(20;22)(q11;q12) [CaseList]     t(20;22)(q11;q12) [Transloc - MCList]   PISD/RBL1 Fusion - MCList]
COSMIC[ PISD ]   [ RBL1 ]
Mitelman database t(22;22)(q11;q11) [CaseList]     t(22;22)(q11;q11) [Transloc - MCList]   THAP7/PRODH Fusion - MCList]
COSMIC[ THAP7 ]   [ PRODH ]
Mitelman database t(22;22)(q12;q12) [CaseList]     t(22;22)(q12;q12) [Transloc - MCList]   APOL3/ISX Fusion - MCList]
COSMIC[ APOL3 ]   [ ISX ]
Mitelman database t(22;22)(q12;q12) [CaseList]     t(22;22)(q12;q12) [Transloc - MCList]   MCM5/TOM1 Fusion - MCList]
COSMIC[ MCM5 ]   [ TOM1 ]
arrayMap arrayMap ((UZH-SIB Zurich)   [auto + random 100 samples .. if exist ]   [tabulated segments]
 
Mitelman databaseSMYD3/ELOVL1[MCList]    SMYD3 (1q44) ELOVL1 (1p34.2)   t(1;1)(p34;q44)
Mitelman databaseGATAD2B/PRKAB2[MCList]    GATAD2B (1q21.3) PRKAB2 (1q21.1)   t(1;1)(q21;q21)
Mitelman databaseZBTB8B/TRAF3IP1[MCList]    ZBTB8B (1p35.1) TRAF3IP1 (2q37.3)   
Mitelman databaseZBTB8B/TRAF3IP1[MCList]    ZBTB8B (1p35.1) TRAF3IP1 (2q37.3)   t(1;2)(p35;q37)
Mitelman databaseREL/MAN1A2[MCList]    REL (2p16.1) MAN1A2 (1p12)   t(1;2)(p12;p16)
TCGA_FusionREL/MAN1A2    REL (2p16.1) MAN1A2 (1p12)
Mitelman databaseATP11B/POU3F1[MCList]    ATP11B (3q26.33) POU3F1 (1p34.3)   t(1;3)(p34;q26)
Mitelman databaseOSCP1/SOX2-OT[MCList]    OSCP1 (1p34.3) SOX2-OT (3q26.33)   
Mitelman databaseOSCP1/SOX2-OT[MCList]    OSCP1 (1p34.3) SOX2-OT (3q26.33)   t(1;3)(p34;q26)
Mitelman databaseBMPR1B/ALG6[MCList]    BMPR1B (4q22.3) ALG6 (1p31.3)   t(1;4)(p31;q22)
Mitelman databaseCTNNA1/HEYL[MCList]    CTNNA1 (5q31.2) HEYL (1p34.3)   
Mitelman databaseCTNNA1/HEYL[MCList]    CTNNA1 (5q31.2) HEYL (1p34.3)   t(1;5)(p34;q31)
Mitelman databaseDARS2/ZFR[MCList]    DARS2 (1q25.1) ZFR (5p13.3)   t(1;5)(q25;p13)
Mitelman databaseSLC7A13/WDTC1[MCList]    SLC7A13 (8q21.3) WDTC1 (1p36.11)   
Mitelman databaseSLC7A13/WDTC1[MCList]    SLC7A13 (8q21.3) WDTC1 (1p36.11)   t(1;8)(p36;q21)
Mitelman databaseNRD1/KCNK9[MCList]    NRD1 (1p32.3) KCNK9 (8q24.3)   t(1;8)(p32;q24)
Mitelman databaseKIF24/FAAH[MCList]    KIF24 (9p13.3) FAAH (1p33)   
Mitelman databaseKIF24/FAAH[MCList]    KIF24 (9p13.3) FAAH (1p33)   t(1;9)(p33;p13)
Mitelman databaseCDK1/USP24[MCList]    CDK1 (10q21.2) USP24 (1p32.3)   t(1;10)(p32;q21)
Mitelman databaseSFMBT2/PRKACB[MCList]    SFMBT2 (10p14) PRKACB (1p31.1)   
Mitelman databaseSFMBT2/PRKACB[MCList]    SFMBT2 (10p14) PRKACB (1p31.1)   t(1;10)(p31;p14)
Mitelman databaseTMEM206/PSAP[MCList]    TMEM206 (1q32.3) PSAP (10q22.1)   
Mitelman databaseTMEM206/PSAP[MCList]    TMEM206 (1q32.3) PSAP (10q22.1)   t(1;10)(q32;q22)
Mitelman databaseETS1/NEGR1[MCList]    ETS1 (11q24.3) NEGR1 (1p31.1)   
Mitelman databaseETS1/NEGR1[MCList]    ETS1 (11q24.3) NEGR1 (1p31.1)   t(1;11)(p31;q24)
Mitelman databaseHMCN1/ETNK1[MCList]    HMCN1 (1q25.3) ETNK1 (12p12.1)   
Mitelman databaseHMCN1/ETNK1[MCList]    HMCN1 (1q25.3) ETNK1 (12p12.1)   t(1;12)(q25;p12)
Mitelman databaseCCP110/GOLPH3L[MCList]    CCP110 (16p12.3) GOLPH3L (1q21.3)   
Mitelman databaseCCP110/GOLPH3L[MCList]    CCP110 (16p12.3) GOLPH3L (1q21.3)   t(1;16)(q21;p12)
Mitelman databaseUNK/DPYD[MCList]    UNK (17q25.1) DPYD (1p21.3)   t(1;17)(p21;q25)
TCGA_FusionUNK/DPYD    UNK (17q25.1) DPYD (1p21.3)
Mitelman databaseALDOC/MAN1A2[MCList]    ALDOC (17q11.2) MAN1A2 (1p12)   t(1;17)(p12;q11)
Mitelman databaseITSN1/MATN1[MCList]    ITSN1 (21q22.11) MATN1 (1p35.2)   t(1;21)(p35;q22)
Mitelman databaseROCK2/SH3YL1[MCList]    ROCK2 (2p25.1) SH3YL1 (2p25.3)   t(2;2)(p25;p25)
Mitelman databaseGPN1/KLHL29[MCList]    GPN1 (2p23.3) KLHL29 (2p24.1)   
Mitelman databaseGPN1/KLHL29[MCList]    GPN1 (2p23.3) KLHL29 (2p24.1)   t(2;2)(p23;p24)
COSMIC_fusionEML4 (2p21) ALK (2p23.2)    [fusion1062] [fusion1063] [fusion1064] [fusion1065] [fusion1127] [fusion1128] [fusion1296] [fusion1297] [fusion1368] [fusion1376] [fusion1539] [fusion1540] [fusion1541] [fusion1542] [fusion1543] [fusion1544] [fusion1545] [fusion408] [fusion409] [fusion410] [fusion411] [fusion413] [fusion414] [fusion462] [fusion463] [fusion464] [fusion465] [fusion473] [fusion474] [fusion475] [fusion476] [fusion477] [fusion478] [fusion479] [fusion480] [fusion487] [fusion488] [fusion489] [fusion490] [fusion491] [fusion493] [fusion730] [fusion731] [fusion732] [fusion733] [fusion734]
Mitelman databaseEML4/ALK[MCList]    EML4 (2p21) ALK (2p23.2)   
Mitelman databaseEML4/ALK[MCList]    EML4 (2p21) ALK (2p23.2)   del(2)(p21p23)
TCGA_FusionEML4/ALK    EML4 (2p21) ALK (2p23.2)
TICdbEML4/ALK    EML4 (2p21) ALK (2p23.2)
TCGA_FusionTHADA/EML4    THADA (2p21) EML4 (2p21)
Mitelman databasePSME4/PPP1CB[MCList]    PSME4 (2p16.2) PPP1CB (2p23.2)   
Mitelman databasePSME4/PPP1CB[MCList]    PSME4 (2p16.2) PPP1CB (2p23.2)   t(2;2)(p16;p23)
Mitelman databaseGPR39/MGAT5[MCList]    GPR39 (2q21.2) MGAT5 (2q21.2)   
Mitelman databaseGPR39/MGAT5[MCList]    GPR39 (2q21.2) MGAT5 (2q21.2)   t(2;2)(q21;q21)
Mitelman databaseACVR1C/MGAT5[MCList]    ACVR1C (2q24.1) MGAT5 (2q21.2)   
Mitelman databaseACVR1C/MGAT5[MCList]    ACVR1C (2q24.1) MGAT5 (2q21.2)   t(2;2)(q21;q24)
Mitelman databaseTNS1/RPRM[MCList]    TNS1 (2q35) RPRM (2q23.3)   
Mitelman databaseTNS1/RPRM[MCList]    TNS1 (2q35) RPRM (2q23.3)   t(2;2)(q23;q35)
Mitelman databaseKCNMB2/NRXN1[MCList]    KCNMB2 (3q26.32) NRXN1 (2p16.3)   
Mitelman databaseKCNMB2/NRXN1[MCList]    KCNMB2 (3q26.32) NRXN1 (2p16.3)   t(2;3)(p16;q26)
Mitelman databaseBCL11A/EPHA5[MCList]    BCL11A (2p16.1) EPHA5 (4q13.1)   
Mitelman databaseBCL11A/EPHA5[MCList]    BCL11A (2p16.1) EPHA5 (4q13.1)   t(2;4)(p16;q13)
Mitelman databaseNRXN1/PLEKHG4B[MCList]    NRXN1 (2p16.3) PLEKHG4B (5p15.33)   t(2;5)(p16;p15)
Mitelman databaseHCN1/FUNDC2P2[MCList]    HCN1 (5p12) FUNDC2P2 (2p11.2)   t(2;5)(p11;p12)
Mitelman databaseUSP37/OSMR[MCList]    USP37 (2q35) OSMR (5p13.1)   t(2;5)(q35;p13)
Mitelman databaseID4/FAM84A[MCList]    ID4 (6p22.3) FAM84A (2p24.3)   
Mitelman databaseID4/FAM84A[MCList]    ID4 (6p22.3) FAM84A (2p24.3)   t(2;6)(p24;p22)
Mitelman databaseANKRD26P1/SLC4A10[MCList]    ANKRD26P1 (16q11.2) SLC4A10 (2q24.2)   
Mitelman databaseANKRD26P1/SLC4A10[MCList]    ANKRD26P1 (16q11.2) SLC4A10 (2q24.2)   t(2;16)(q24;q11)
Mitelman databaseCRHR1-IT1/ALLC[MCList]    CRHR1-IT1 (-) ALLC (2p25.3)   
Mitelman databaseCRHR1-IT1/ALLC[MCList]    CRHR1-IT1 (-) ALLC (2p25.3)   t(2;17)(p25;q21)
Mitelman databaseKLHL29/PSMA8[MCList]    KLHL29 (2p24.1) PSMA8 (18q11.2)   t(2;18)(p24;q11)
Mitelman databaseEVA1A/TTC28[MCList]    EVA1A (2p12) TTC28 (22q12.1)   
Mitelman databaseEVA1A/TTC28[MCList]    EVA1A (2p12) TTC28 (22q12.1)   t(2;22)(p12;q12)
Mitelman databasePAK2/VGLL3[MCList]    PAK2 (3q29) VGLL3 (3p12.1)   t(3;3)(p12;q29)
Mitelman databaseALCAM/EPHA6[MCList]    ALCAM (3q13.11) EPHA6 (3q11.2)   t(3;3)(q11;q13)
Mitelman databaseGSK3B/IMPG2[MCList]    GSK3B (3q13.33) IMPG2 (3q12.3)   t(3;3)(q12;q13)
Mitelman databaseSLCO2A1/GUCA1C[MCList]    SLCO2A1 (3q22.1) GUCA1C (3q13.13)   t(3;3)(q13;q22)
Mitelman databaseRUVBL1/TMCC1[MCList]    RUVBL1 (3q21.3) TMCC1 (3q22.1)   
Mitelman databaseRUVBL1/TMCC1[MCList]    RUVBL1 (3q21.3) TMCC1 (3q22.1)   t(3;3)(q21;q22)
Mitelman databasePIK3CB/BFSP2[MCList]    PIK3CB (3q22.3) BFSP2 (3q22.1)   
Mitelman databasePIK3CB/BFSP2[MCList]    PIK3CB (3q22.3) BFSP2 (3q22.1)   t(3;3)(q22;q22)
TCGA_FusionPIK3CB/BFSP2    PIK3CB (3q22.3) BFSP2 (3q22.1)
Mitelman databaseTMCC1/C3orf36[MCList]    TMCC1 (3q22.1) C3orf36 (3q22.1)   t(3;3)(q22;q22)
Mitelman databaseHLTF/OTOL1[MCList]    HLTF (3q24) OTOL1 (3q26.1)   
Mitelman databaseHLTF/OTOL1[MCList]    HLTF (3q24) OTOL1 (3q26.1)   t(3;3)(q24;q26)
TCGA_FusionGMPS/C3orf55    GMPS (3q25.31) C3orf55 (LUSC)
Mitelman databaseIQCJ/BCHE[MCList]    IQCJ (3q25.32) BCHE (3q26.1)   
Mitelman databaseIQCJ/BCHE[MCList]    IQCJ (3q25.32) BCHE (3q26.1)   t(3;3)(q25;q26)
Mitelman databasePPM1L/MCF2L2[MCList]    PPM1L (3q25.33) MCF2L2 (3q27.1)   
Mitelman databasePPM1L/MCF2L2[MCList]    PPM1L (3q25.33) MCF2L2 (3q27.1)   t(3;3)(q25;q27)
Mitelman databasePYDC2/C3orf79[MCList]    PYDC2 (3q28) C3orf79 (3q25.2)   
Mitelman databasePYDC2/C3orf79[MCList]    PYDC2 (3q28) C3orf79 (3q25.2)   t(3;3)(q25;q28)
Mitelman databaseATP11B/SI[MCList]    ATP11B (3q26.33) SI (3q26.1)   t(3;3)(q26;q26)
Mitelman databasePHC3/FNDC3B[MCList]    PHC3 (3q26.2) FNDC3B (3q26.31)   
Mitelman databasePHC3/FNDC3B[MCList]    PHC3 (3q26.2) FNDC3B (3q26.31)   t(3;3)(q26;q26)
TCGA_FusionPHC3/FNDC3B    PHC3 (3q26.2) FNDC3B (3q26.31)
Mitelman databaseCCDC39/MCF2L2[MCList]    CCDC39 (3q26.33) MCF2L2 (3q27.1)   
Mitelman databaseCCDC39/MCF2L2[MCList]    CCDC39 (3q26.33) MCF2L2 (3q27.1)   t(3;3)(q26;q27)
Mitelman databaseSOX2/TPRG1[MCList]    SOX2 (3q26.33) TPRG1 (3q28)   
Mitelman databaseSOX2/TPRG1[MCList]    SOX2 (3q26.33) TPRG1 (3q28)   t(3;3)(q26;q28)
Mitelman databaseLPP/ST6GAL1[MCList]    LPP (3q28) ST6GAL1 (3q27.3)   t(3;3)(q27;q28)
TCGA_FusionLPP/ST6GAL1    LPP (3q28) ST6GAL1 (3q27.3)
Mitelman databaseEHHADH/SENP5[MCList]    EHHADH (3q27.2) SENP5 (3q29)   t(3;3)(q27;q29)
Mitelman databaseATP11B/ZNF595[MCList]    ATP11B (3q26.33) ZNF595 (4p16.3)   t(3;4)(q26;p16)
Mitelman databaseMCF2L2/MIR548A3[MCList]    MCF2L2 (3q27.1) MIR548A3 (3q13.11)   t(3;8)(q27;q22)
Mitelman databasePDE3B/ATP11B[MCList]    PDE3B (11p15.2) ATP11B (3q26.33)   
Mitelman databasePDE3B/ATP11B[MCList]    PDE3B (11p15.2) ATP11B (3q26.33)   t(3;11)(q26;p15)
Mitelman databaseTNFSF13B/MYLK[MCList]    TNFSF13B (13q33.3) MYLK (3q21.1)   
Mitelman databaseTNFSF13B/MYLK[MCList]    TNFSF13B (13q33.3) MYLK (3q21.1)   t(3;13)(q21;q33)
Mitelman databaseMAP2K3/SSR3[MCList]    MAP2K3 (17p11.2) SSR3 (3q25.31)   t(3;17)(q25;p11)
Mitelman databaseMIR21/WDR53[MCList]    MIR21 (17q23.1) WDR53 (3q29)   
Mitelman databaseMIR21/WDR53[MCList]    MIR21 (17q23.1) WDR53 (3q29)   t(3;17)(q29;q23)
Mitelman databaseACTN4/IGF2BP2[MCList]    ACTN4 (19q13.2) IGF2BP2 (3q27.2)   t(3;19)(q27;q13)
Mitelman databaseSLC12A8/BCAS1[MCList]    SLC12A8 (3q21.2) BCAS1 (20q13.2)   t(3;20)(q21;q13)
TCGA_FusionSLC12A8/BCAS1    SLC12A8 (3q21.2) BCAS1 (20q13.2)
Mitelman databasePOU1F1/TMPRSS15[MCList]    POU1F1 (3p11.2) TMPRSS15 (21q21.1)   t(3;21)(p11;q21)
Mitelman databaseATP11B/TPTEP1[MCList]    ATP11B (3q26.33) TPTEP1 (22q11.1)   t(3;22)(q26;q11)
COSMIC_fusionFGFR3 (4p16.3) TACC3 (4p16.3)    [fusion1348] [fusion1349] [fusion1350] [fusion1351] [fusion1352] [fusion1353] [fusion1354] [fusion1355] [fusion1356] [fusion1357] [fusion1358] [fusion1359] [fusion1360] [fusion1361] [fusion1434] [fusion1435]
Mitelman databaseFGFR3/TACC3[MCList]    FGFR3 (4p16.3) TACC3 (4p16.3)   del(4)(p16p16)
TCGA_FusionFGFR3/TACC3    FGFR3 (4p16.3) TACC3 (4p16.3)
TICdbFGFR3/TACC3    FGFR3 (4p16.3) TACC3 (4p16.3)
Mitelman databaseCCSER1/UGT2A1[MCList]    CCSER1 (4q22.1) UGT2A1 (4q13.2)   t(4;4)(q13;q22)
COSMIC_fusionSLC34A2 (4p15.2) ROS1 (6q22.1)    [fusion1196] [fusion1197] [fusion1198] [fusion1259] [fusion1260] [fusion1261] [fusion1618]
Fusion_CancerSLC34A2/ROS1 [FUSC003670]    SLC34A2 (4p15.2) ROS1 (6q22.1)
Mitelman databaseSLC34A2/ROS1[MCList]    SLC34A2 (4p15.2) ROS1 (6q22.1)   t(4;6)(p15;q22)
TICdbSLC34A2/ROS1    SLC34A2 (4p15.2) ROS1 (6q22.1)
Mitelman databaseCOX18/ZFAT[MCList]    COX18 (4q13.3) ZFAT (8q24.22)   
Mitelman databaseCOX18/ZFAT[MCList]    COX18 (4q13.3) ZFAT (8q24.22)   t(4;8)(q13;q24)
Mitelman databaseADAMTS3/SNX30[MCList]    ADAMTS3 (4q13.3) SNX30 (9q32)   
Mitelman databaseADAMTS3/SNX30[MCList]    ADAMTS3 (4q13.3) SNX30 (9q32)   t(4;9)(q13;q32)
Mitelman databaseSGMS1/KCTD8[MCList]    SGMS1 (10q11.23) KCTD8 (4p13)   t(4;10)(p13;q11)
Mitelman databaseMARCH6/IRX4[MCList]    MARCH6 (5p15.2) IRX4 (5p15.33)   
Mitelman databaseMARCH6/IRX4[MCList]    MARCH6 (5p15.2) IRX4 (5p15.33)   t(5;5)(p15;p15)
Mitelman databaseROPN1L/SEMA5A[MCList]    ROPN1L (5p15.2) SEMA5A (5p15.31)   
Mitelman databaseROPN1L/SEMA5A[MCList]    ROPN1L (5p15.2) SEMA5A (5p15.31)   t(5;5)(p15;p15)
Mitelman databaseRICTOR/FGF10[MCList]    RICTOR (5p13.1) FGF10 (5p12)   t(5;5)(p12;p13)
COSMIC_fusionCD74 (5q32) ROS1 (6q22.1)    [fusion1200] [fusion1201] [fusion1202] [fusion1203] [fusion1478] [fusion1619]
Fusion_CancerCD74/ROS1 [FUSC003425]    CD74 (5q32) ROS1 (6q22.1)
Mitelm